| Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors W Yu, EJ Chory, AK Wernimont, W Tempel, A Scopton, A Federation, ... Nature communications 3 (1), 1288, 2012 | 296 | 2012 |
| Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2 W Zheng, G Ibáñez, H Wu, G Blum, H Zeng, A Dong, F Li, T Hajian, ... Journal of the American Chemical Society 134 (43), 18004-18014, 2012 | 154 | 2012 |
| Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2 XB Lei, YY Chen, GH Du, WY Yu, XH Wang, H Qu, B Xia, HP He, JH Mao, ... | 152 | 2006 |
| Beclin 1-independent autophagy induced by a Bcl-XL/Bcl-2 targeting compound, Z18 S Tian, J Lin, J Zhou, X Wang, Y Li, X Ren, W Yu, W Zhong, J Xiao, ... Autophagy 6 (8), 1032-1041, 2010 | 109 | 2010 |
| Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8 A Ma, W Yu, F Li, RM Bleich, JM Herold, KV Butler, JL Norris, V Korboukh, ... Journal of medicinal chemistry 57 (15), 6822-6833, 2014 | 94 | 2014 |
| Nahuoic Acid A Produced by a Streptomyces sp. Isolated From a Marine Sediment Is a Selective SAM-Competitive Inhibitor of the Histone Methyltransferase SETD8 DE Williams, DS Dalisay, F Li, J Amphlett, W Maneerat, MAG Chavez, ... Organic letters 15 (2), 414-417, 2013 | 75 | 2013 |
| Bromo-deaza-SAH: a potent and selective DOT1L inhibitor W Yu, D Smil, F Li, W Tempel, O Fedorov, KT Nguyen, Y Bolshan, ... Bioorganic & medicinal chemistry 21 (7), 1787-1794, 2013 | 70 | 2013 |
| The dynamic conformational landscape of the protein methyltransferase SETD8 S Chen, RP Wiewiora, F Meng, N Babault, A Ma, W Yu, K Qian, H Hu, ... Elife 8, e45403, 2019 | 42 | 2019 |
| A novel Bcl-XL inhibitor Z36 that induces autophagic cell death in Hela cells J Lin, Z Zheng, Y Li, W Yu, W Zhong, S Tian, F Zhao, X Ren, J Xiao, ... Autophagy 5 (3), 314-320, 2009 | 42 | 2009 |
| Structure-based design of a covalent inhibitor of the SET domain-containing protein 8 (SETD8) lysine methyltransferase KV Butler, A Ma, W Yu, F Li, W Tempel, N Babault, F Pittella-Silva, J Shao, ... Journal of medicinal chemistry 59 (21), 9881-9889, 2016 | 38 | 2016 |
| New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms SS Spurr, ED Bayle, W Yu, F Li, W Tempel, M Vedadi, M Schapira, ... Bioorganic & Medicinal Chemistry Letters 26 (18), 4518-4522, 2016 | 31 | 2016 |
| Structure–activity relationship studies of SETD8 inhibitors A Ma, W Yu, Y Xiong, KV Butler, PJ Brown, J Jin MedChemComm 5 (12), 1892-1898, 2014 | 31 | 2014 |
| Solution structure of human ζ-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats W Yu, J Lin, C Jin, B Xia Journal of molecular biology 386 (4), 903-912, 2009 | 29 | 2009 |
| A scintillation proximity assay for histone demethylases W Yu, MS Eram, T Hajian, A Szykowska, N Burgess-Brown, M Vedadi, ... Analytical biochemistry 463, 54-60, 2014 | 21 | 2014 |
| Structural and functional characterization of tumor suppressors TIG3 and H-REV107 H Wei, L Wang, X Ren, W Yu, J Lin, C Jin, B Xia FEBS letters 589 (11), 1179-1186, 2015 | 18 | 2015 |
| Turning a substrate peptide into a potent inhibitor for the histone methyltransferase SETD8 RA Judge, H Zhu, AK Upadhyay, PM Bodelle, CW Hutchins, M Torrent, ... ACS Medicinal Chemistry Letters 7 (12), 1102-1106, 2016 | 11 | 2016 |
| Solution structure of GSP13 from Bacillus subtilis exhibits an S1 domain related to cold shock proteins W Yu, J Hu, B Yu, W Xia, C Jin, B Xia Journal of biomolecular NMR 43, 255-259, 2009 | 9 | 2009 |
| 1H, 13C, and 15N resonance assignments of the N-terminal domain of human TIG3 L Wang, W Yu, X Ren, J Lin, C Jin, B Xia Biomolecular NMR assignments 6, 201-203, 2012 | 6 | 2012 |
| 1H, 13C, and 15N resonance assignments of a general stress protein GSP13 from Bacillus subtilis W Yu, B Yu, J Hu, W Xia, C Jin, B Xia Biomolecular NMR assignments 2, 163-165, 2008 | 2 | 2008 |
| 1H, 13C, and 15N resonance assignments of human ζ-COP W Yu, C Jin, B Xia Biomolecular NMR Assignments 2, 73-75, 2008 | 2 | 2008 |
