| The Ig-like structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy I Krimm, C Östlund, B Gilquin, J Couprie, P Hossenlopp, JP Mornon, ... Structure 10 (6), 811-823, 2002 | 322 | 2002 |
| The carboxyl-terminal region common to lamins A and C contains a DNA binding domain V Stierlé, J Couprie, C Östlund, I Krimm, S Zinn-Justin, P Hossenlopp, ... Biochemistry 42 (17), 4819-4828, 2003 | 231 | 2003 |
| NMR-based analysis of protein–ligand interactions O Cala, F Guillière, I Krimm Analytical and bioanalytical chemistry 406, 943-956, 2014 | 193 | 2014 |
| Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities A Ahmed-Belkacem, L Colliandre, N Ahnou, Q Nevers, M Gelin, Y Bessin, ... Nature communications 7 (1), 12777, 2016 | 90 | 2016 |
| NMR structures and activity of a novel α-like toxin from the scorpion Leiurus quinquestriatus hebraeus I Krimm, N Gilles, P Sautière, M Stankiewicz, M Pelhate, D Gordon, ... Journal of molecular biology 285 (4), 1749-1763, 1999 | 86 | 1999 |
| Fragment-Based Deconstruction of Bcl-xL Inhibitors S Barelier, J Pons, O Marcillat, JM Lancelin, I Krimm Journal of medicinal chemistry 53 (6), 2577-2588, 2010 | 84 | 2010 |
| Biochemical Characterization and Nuclear Magnetic Resonance Structure of Novel α-Conotoxins Isolated from the Venom of Conus consors, P Favreau, I Krimm, F Le Gall, MJ Bobenrieth, H Lamthanh, F Bouet, ... Biochemistry 38 (19), 6317-6326, 1999 | 75 | 1999 |
| Glutathionylation induces the dissociation of 1-Cys D-peroxiredoxin non-covalent homodimer V rie Noguera-Mazon, J roˆ me Lemoine, O Walker, N Rouhier, ... The Journal of biological chemistry 281 (42), 31736-31742, 2006 | 74 | 2006 |
| Fragment linking strategies for structure-based drug design A Bancet, C Raingeval, T Lomberget, M Le Borgne, JF Guichou, I Krimm Journal of Medicinal Chemistry 63 (20), 11420-11435, 2020 | 72 | 2020 |
| The single mutation Trp35←Ala in the 35−40 redox site of Chlamydomonas reinhardtii thioredoxin h affects its biochemical activity and the pH dependence of C36−C39 1H … I Krimm, S Lemaire, E Ruelland, M Miginiac‐Maslow, JP Jaquot, ... European journal of biochemistry 255 (1), 185-195, 1998 | 72 | 1998 |
| Ligand specificity in fragment-based drug design S Barelier, J Pons, K Gehring, JM Lancelin, I Krimm Journal of medicinal chemistry 53 (14), 5256-5266, 2010 | 70 | 2010 |
| Ligand-orientation based fragment selection in STD NMR screening O Cala, I Krimm Journal of Medicinal Chemistry 58 (21), 8739-8742, 2015 | 58 | 2015 |
| A coil–helix instead of a helix–coil motif can be induced in a chloroplast transit peptide from Chlamydomonas reinhardtii I Krimm, P Gans, JF Hernandez, GJ Arlaud, JM Lancelin European journal of biochemistry 265 (1), 171-180, 1999 | 58 | 1999 |
| Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor S Igonet, C Raingeval, E Cecon, M Pučić-Baković, G Lauc, O Cala, ... Scientific Reports 8 (1), 8142, 2018 | 57 | 2018 |
| Ligand specificity, privileged substructures and protein druggability from fragment-based screening S Barelier, I Krimm Current Opinion in Chemical Biology 15 (4), 469-474, 2011 | 57 | 2011 |
| Crystal structure and solution NMR dynamics of a D (type II) peroxiredoxin glutaredoxin and thioredoxin dependent: a new insight into the peroxiredoxin oligomerism A Echalier, X Trivelli, C Corbier, N Rouhier, O Walker, P Tsan, JP Jacquot, ... Biochemistry 44 (6), 1755-1767, 2005 | 56 | 2005 |
| Characterization of the yeast peroxiredoxin Ahp1 in its reduced active and overoxidized inactive forms using NMR X Trivelli, I Krimm, C Ebel, L Verdoucq, V Prouzet-Mauléon, Y Chartier, ... Biochemistry 42 (48), 14139-14149, 2003 | 49 | 2003 |
| 1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery C Raingeval, O Cala, B Brion, M Le Borgne, RE Hubbard, I Krimm Journal of enzyme inhibition and medicinal chemistry 34 (1), 1218-1225, 2019 | 46 | 2019 |
| Structural implications on the interaction of scorpion α‐like toxins with the sodium channel receptor site inferred from toxin iodination and pH‐dependent binding N Gilles, I Krimm, F Bouet, O Froy, M Gurevitz, JM Lancelin, D Gordon Journal of neurochemistry 75 (4), 1735-1745, 2000 | 46 | 2000 |
| Overview of Probing Protein‐Ligand Interactions Using NMR C Aguirre, O Cala, I Krimm Current protocols in protein science 81 (1), 17.18. 1-17.18. 24, 2015 | 44 | 2015 |
