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William Klunk
William Klunk
Adresse e-mail validée de pitt.edu
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The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for …
GM McKhann, DS Knopman, H Chertkow, BT Hyman, CR Jack Jr, ...
Alzheimer's & dementia 7 (3), 263-269, 2011
156332011
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B
WE Klunk, H Engler, A Nordberg, Y Wang, G Blomqvist, DP Holt, ...
Annals of Neurology: Official Journal of the American Neurological …, 2004
51992004
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
RJ Bateman, C Xiong, TLS Benzinger, AM Fagan, A Goate, NC Fox, ...
New England Journal of Medicine 367 (9), 795-804, 2012
39742012
Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory
RL Buckner, AZ Snyder, BJ Shannon, G LaRossa, R Sachs, AF Fotenos, ...
Journal of neuroscience 25 (34), 7709-7717, 2005
23502005
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease
S Salloway, R Sperling, NC Fox, K Blennow, W Klunk, M Raskind, ...
New England Journal of Medicine 370 (4), 322-333, 2014
20492014
Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Aβ42 in humans
AM Fagan, MA Mintun, RH Mach, SY Lee, CS Dence, AR Shah, ...
Annals of neurology 59 (3), 512-519, 2006
15072006
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ...
Jama 313 (19), 1924-1938, 2015
14892015
Imaging β-amyloid burden in aging and dementia
CC Rowe, S Ng, U Ackermann, SJ Gong, K Pike, G Savage, TF Cowie, ...
Neurology 68 (20), 1718-1725, 2007
12582007
Frequent amyloid deposition without significant cognitive impairment among the elderly
HJ Aizenstein, RD Nebes, JA Saxton, JC Price, CA Mathis, ND Tsopelas, ...
Archives of neurology 65 (11), 1509-1517, 2008
12482008
[11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease
MA Mintun, GN Larossa, YI Sheline, CS Dence, SY Lee, RH Mach, ...
Neurology 67 (3), 446-452, 2006
12172006
Synthesis and Evaluation of 11C-Labeled 6-Substituted 2-Arylbenzothiazoles as Amyloid Imaging Agents
CA Mathis, Y Wang, DP Holt, GF Huang, ML Debnath, WE Klunk
Journal of medicinal chemistry 46 (13), 2740-2754, 2003
11582003
Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
MD Ikonomovic, WE Klunk, EE Abrahamson, CA Mathis, JC Price, ...
Brain 131 (6), 1630-1645, 2008
11012008
11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment
CR Jack Jr, VJ Lowe, ML Senjem, SD Weigand, BJ Kemp, MM Shiung, ...
Brain 131 (3), 665-680, 2008
10422008
Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease
VL Villemagne, KE Pike, G Chételat, KA Ellis, RS Mulligan, P Bourgeat, ...
Annals of neurology 69 (1), 181-192, 2011
9912011
β-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease
KE Pike, G Savage, VL Villemagne, S Ng, SA Moss, P Maruff, CA Mathis, ...
Brain 130 (11), 2837-2844, 2007
9562007
Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
EM Reiman, K Chen, X Liu, D Bandy, M Yu, W Lee, N Ayutyanont, ...
Proceedings of the National Academy of Sciences 106 (16), 6820-6825, 2009
9202009
Brain imaging in Alzheimer disease
KA Johnson, NC Fox, RA Sperling, WE Klunk
Cold Spring Harbor perspectives in medicine 2 (4), a006213, 2012
8632012
11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled …
JO Rinne, DJ Brooks, MN Rossor, NC Fox, R Bullock, WE Klunk, ...
The Lancet Neurology 9 (4), 363-372, 2010
8542010
Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation.
WE Klunk, JW Pettegrew, DJ Abraham
Journal of Histochemistry & Cytochemistry 37 (8), 1273-1281, 1989
7911989
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B
JC Price, WE Klunk, BJ Lopresti, X Lu, JA Hoge, SK Ziolko, DP Holt, ...
Journal of Cerebral Blood Flow & Metabolism 25 (11), 1528-1547, 2005
7772005
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