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Michael W Pickup
Michael W Pickup
Stemcentrx
Adresse e-mail validée de abbvie.com
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The extracellular matrix modulates the hallmarks of cancer
MW Pickup, JK Mouw, VM Weaver
EMBO reports 15 (12), 1243-1253, 2014
18082014
The roles of TGFβ in the tumour microenvironment
M Pickup, S Novitskiy, HL Moses
Nature Reviews Cancer 13 (11), 788-799, 2013
9932013
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
H Laklai, YA Miroshnikova, MW Pickup, EA Collisson, GE Kim, AS Barrett, ...
Nature medicine 22 (5), 497-505, 2016
5572016
Gr-1+ CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung
HH Yan, M Pickup, Y Pang, AE Gorska, Z Li, A Chytil, Y Geng, JW Gray, ...
Cancer research 70 (15), 6139-6149, 2010
4142010
Tissue mechanics promote IDH1-dependent HIF1α–tenascin C feedback to regulate glioblastoma aggression
YA Miroshnikova, JK Mouw, JM Barnes, MW Pickup, JN Lakins, Y Kim, ...
Nature cell biology 18 (12), 1336-1345, 2016
3212016
Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β–deficient mouse mammary carcinomas
MW Pickup, H Laklai, I Acerbi, P Owens, AE Gorska, A Chytil, M Aakre, ...
Cancer research 73 (17), 5336-5346, 2013
2072013
From transformation to metastasis: deconstructing the extracellular matrix in breast cancer
S Kaushik, MW Pickup, VM Weaver
Cancer and Metastasis Reviews 35, 655-667, 2016
1662016
TGF-β receptor II loss promotes mammary carcinoma progression by Th17-dependent mechanisms
SV Novitskiy, MW Pickup, AE Gorska, P Owens, A Chytil, M Aakre, H Wu, ...
Cancer discovery 1 (5), 430-441, 2011
1572011
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional …
AH Mekhdjian, FB Kai, MG Rubashkin, LS Prahl, LM Przybyla, ...
Molecular biology of the cell 28 (11), 1467-1488, 2017
1392017
Role of TGF-β signaling in generation of CD39+ CD73+ myeloid cells in tumors
SV Ryzhov, MW Pickup, A Chytil, AE Gorska, Q Zhang, P Owens, ...
The Journal of Immunology 193 (6), 3155-3164, 2014
1222014
Inhibition of BMP signaling suppresses metastasis in mammary cancer
P Owens, MW Pickup, SV Novitskiy, JM Giltnane, AE Gorska, CR Hopkins, ...
Oncogene 34 (19), 2437-2449, 2015
1152015
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators
P Owens, MW Pickup, SV Novitskiy, A Chytil, AE Gorska, ME Aakre, ...
Proceedings of the National Academy of Sciences 109 (8), 2814-2819, 2012
942012
ALCAM/CD166 Is a TGF-β–responsive marker and functional regulator of prostate cancer metastasis to bone
AG Hansen, SA Arnold, M Jiang, TD Palmer, T Ketova, A Merkel, ...
Cancer research 74 (5), 1404-1415, 2014
892014
Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties
SV Novitskiy, MW Pickup, A Chytil, D Polosukhina, P Owens, HL Moses
Journal of leukocyte biology 92 (3), 641-651, 2012
892012
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression
EC Woods, FB Kai, JM Barnes, K Pedram, MW Pickup, MJ Hollander, ...
Elife 6, e25752, 2017
812017
Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk
LA Matise, TD Palmer, WJ Ashby, A Nashabi, A Chytil, M Aakre, ...
Breast cancer research 14, 1-18, 2012
812012
TGF-β, bone morphogenetic protein, and activin signaling and the tumor microenvironment
MW Pickup, P Owens, HL Moses
Cold Spring Harbor perspectives in biology 9 (5), a022285, 2017
672017
Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer
B Jovanović, JS Beeler, MW Pickup, A Chytil, AE Gorska, WJ Ashby, ...
Breast Cancer Research 16, 1-14, 2014
642014
Stromal matrix metalloproteinase 2 regulates collagen expression and promotes the outgrowth of experimental metastases
AL Bates, MW Pickup, MA Hallett, EA Dozier, S Thomas, B Fingleton
The Journal of pathology 235 (5), 773-783, 2015
632015
α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site
YA Miroshnikova, GI Rozenberg, L Cassereau, M Pickup, JK Mouw, G Ou, ...
Molecular biology of the cell 28 (22), 2958-2977, 2017
622017
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