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Maxx Holmes
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Multi-scale approaches for the simulation of cardiac electrophysiology: I–Sub-cellular and stochastic calcium dynamics from cell to organ
MA Colman, M Holmes, DG Whittaker, I Jayasinghe, AP Benson
Methods 185, 49-59, 2021
132021
Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics
M Holmes, ME Hurley, TMD Sheard, AP Benson, I Jayasinghe, ...
Philosophical Transactions of the Royal Society B 377 (1864), 20210317, 2022
52022
Sub-cellular Heterogeneity in SERCA Determines Spatial Calcium Dynamics in Cardiomyocytes
M Holmes, ME Hurley, TMD Sheard, HJ Stevenson-Cocks, A Benson, ...
Biophysical Journal 118 (3), 172a-173a, 2020
12020
Investigating calcium-mediated arrhythmias via a computational model of a rabbit atrial myocyte
M Holmes, AP Benson, OV Aslanidi, MA Colman
2018 Computing in Cardiology Conference (CinC) 45, 1-4, 2018
12018
Cardiac Digital Twin Pipeline for Virtual Therapy Evaluation
J Camps, ZJ Wang, R Doste, M Holmes, B Lawson, J Tomek, K Burrage, ...
arXiv preprint arXiv:2401.10029, 2024
2024
The Influence of Calcium Handling Variability on Cardiac Electrophysiology in Ventricular and Atrial Myocytes
M Holmes
University of Leeds, 2021
2021
Sensitivity of ECG and ejection fraction to human electromechanical myocardial properties in post-myocardial infarction
ZJ Wang, M Holmes, R Doste, J Camps, X Zhou, B Rodriguez
Online Supplement: Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics
M Holmes, ME Hurley, TMD Sheard, AP Benson, I Jayasinghe, ...
A Novel Model of the Rabbit Atrial Myocyte for the Study of Ca2+ Mediated Arrhythmia
M Holmes, AP Benson, OV Aslanidi, MA Colman
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Articles 1–9