Suivre
Masayuki Kai
Masayuki Kai
Kyowa Kirin, Inc. -US
Adresse e-mail validée de kyowakirin.com
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Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells
VP Sharma, R Eddy, D Entenberg, M Kai, FB Gertler, J Condeelis
Current Biology 23 (21), 2079-2089, 2013
1962013
Expression and Imprinting Status of Human PEG8/IGF2AS, a Paternally Expressed Antisense Transcript from the IGF2 Locus, in Wilms' Tumors
T Okutsu, Y Kuroiwa, F Kagitani, M Kai, K Aisaka, O Tsutsumi, Y Kaneko, ...
The journal of biochemistry 127 (3), 475-483, 2000
932000
Agonist antibody to human thrombopoietin receptor
M Kai, K Motoki, S Kataoka, H Yoshida, T Hagiwara
US Patent 8,048,421, 2011
482011
Switching constant domains enhances agonist activities of antibodies to a thrombopoietin receptor
M Kai, K Motoki, H Yoshida, C Emuta, Y Chisaka, K Tsuruhata, C Endo, ...
Nature Biotechnology 26 (2), 209-211, 2008
482008
Estrogen agonists, 17β-estradiol, bisphenol A, and diethylstilbestrol, decrease cortactin expression in the mouse testis
R Anahara, M Yoshida, Y Toyama, M Maekawa, M Kai, F Ishino, ...
Archives of histology and cytology 69 (2), 101-107, 2006
352006
The Novel Dominant Mutation Dspd Leads to a Severe Spermiogenesis Defect in Mice
M Kai, M Irie, T Okutsu, K Inoue, N Ogonuki, H Miki, M Yokoyama, ...
Biology of reproduction 70 (4), 1213-1221, 2004
302004
Flutamide depresses expression of cortactin in the ectoplasmic specialization between the Sertoli cells and spermatids in the mouse testis
R Anahara, Y Toyama, M Maekawa, M Kai, F Ishino, K Toshimori, C Mori
Food and chemical toxicology 44 (7), 1050-1056, 2006
292006
Disruption of CCR1-mediated myeloid cell accumulation suppresses colorectal cancer progression in mice
Y Kiyasu, K Kawada, H Hirai, R Ogawa, K Hanada, H Masui, G Nishikawa, ...
Cancer letters 487, 53-62, 2020
162020
Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in …
R Anahara, Y Toyama, M Maekawa, M Yoshida, M Kai, F Ishino, ...
Biochemical and biophysical research communications 346 (1), 276-280, 2006
152006
An antibody-drug conjugate that selectively targets human monocyte progenitors for anti-cancer therapy
Y Izumi, M Kanayama, Z Shen, M Kai, S Kawamura, M Akiyama, ...
Frontiers in Immunology 12, 618081, 2021
122021
Domain subclass conversion improved activity of anti-Mpl agonist antibodies in the form of whole IgG.
M Kai, K Motoki, H Yoshida, K Tsuruhata, C Endo, M Muto, C Emuta, ...
Blood, The Journal of the American Society of Hematology 108 (11), 1134-1134, 2006
122006
Agonist antibody to human thrombopoietin receptor
M Kai, K Motoki, S Kataoka, H Yoshida, T Hagiwara
US Patent 8,236,314, 2012
102012
In vivo efficacy of anti-MPL agonist antibody in promoting primary human hematopoietic cells
M Kai, T Hagiwara, C Emuta, Y Chisaka, K Tsuruhata, C Endo, Y Inagaki, ...
Blood, The Journal of the American Society of Hematology 113 (10), 2213-2216, 2009
32009
Anti-human CCR1 monoclonal antibody
M Kai, S Ogawa, M Taketo, K Kawada, H Hirai, Y Sakai, T Maekawa
US Patent 11,912,775, 2024
2024
Anti-human ccr1 monoclonal antibody
M Kai, S Ogawa, M Taketo, K Kawada, H Hirai, Y Sakai, T Maekawa
US Patent App. 18/459,844, 2024
2024
BISPECIFIC ANTIBODIES CAPABLE OF BINDING TO CD40 AND GPC3
Y SUMITOMO, M Kai
2023
TRANSFERRIN RECEPTOR (TFR) BISPECIFIC ANTIBODY
K Mitamura, R Nakano, M Kai, N Takahashi
2022
Bispecific antibody binding to cd40 and gpc3
Y Sumitomo, M Kai
US Patent App. 17/611,344, 2022
2022
BISPECIFIC ANTIBODY BINDING TO TfR
K Mitamura, R Nakano, M Kai, N Takahashi
US Patent App. 17/418,447, 2022
2022
Anticorpo biespecífico de ligação ao tfr
K MITAMURA, R Nakano, M Kai, N Takahashi
2021
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