Koen Schepers
Koen Schepers
Leiden University Medical Center
Adresse e-mail validée de lumc.nl
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Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche
K Schepers, EM Pietras, D Reynaud, J Flach, M Binnewies, T Garg, ...
Cell stem cell 13 (3), 285-299, 2013
4282013
Normal and leukemic stem cell niches: insights and therapeutic opportunities
K Schepers, TB Campbell, E Passegué
Cell stem cell 16 (3), 254-267, 2015
2662015
One naive T cell, multiple fates in CD8+ T cell differentiation
C Gerlach, JWJ van Heijst, E Swart, D Sie, N Armstrong, RM Kerkhoven, ...
Journal of Experimental Medicine 207 (6), 1235-1246, 2010
1912010
Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils
AJ Casbon, D Reynaud, C Park, E Khuc, DD Gan, K Schepers, ...
Proceedings of the National Academy of Sciences 112 (6), E566-E575, 2015
1822015
Tumor Rejection Induced by CD70-mediated Quantitative and Qualitative Effects on Effector CD8+ T Cell Formation
R Arens, K Schepers, MA Nolte, MF Van Oosterwijk, RAW Van Lier, ...
The Journal of experimental medicine 199 (11), 1595-1605, 2004
1762004
Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient
JWJ van Heijst, C Gerlach, E Swart, D Sie, C Nunes-Alves, RM Kerkhoven, ...
Science 325 (5945), 1265-1269, 2009
1402009
JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal
M Santaguida, K Schepers, B King, AJ Sabnis, EC Forsberg, JL Attema, ...
Cancer cell 15 (4), 341-352, 2009
1242009
Dissecting T cell lineage relationships by cellular barcoding
K Schepers, E Swart, JWJ van Heijst, C Gerlach, M Castrucci, D Sie, ...
The Journal of experimental medicine 205 (10), 2309-2318, 2008
1082008
Differential kinetics of antigen-specific CD4+ and CD8+ T cell responses in the regression of retrovirus-induced sarcomas
K Schepers, M Toebes, G Sotthewes, FA Vyth-Dreese, TAM Dellemijn, ...
The Journal of Immunology 169 (6), 3191-3199, 2002
1002002
Effective postexposure treatment of retrovirus-induced disease with immunostimulatory DNA containing CpG motifs
ARM Olbrich, S Schimmer, K Heeg, K Schepers, TNM Schumacher, ...
Journal of virology 76 (22), 11397-11404, 2002
722002
Activated Gs signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice
K Schepers, EC Hsiao, T Garg, MJ Scott, E Passegué
Blood 120 (17), 3425-3435, 2012
632012
Generation of T cell help through a MHC class I-restricted TCR
HWHG Kessels, K Schepers, MD van den Boom, DJ Topham, ...
The Journal of Immunology 177 (2), 976-982, 2006
582006
CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40
M MacLeod, MJ Kwakkenbos, A Crawford, S Brown, B Stockinger, ...
The Journal of experimental medicine 203 (4), 897-906, 2006
542006
Independent roles of perforin, granzymes, and Fas in the control of Friend retrovirus infection
G Zelinskyy, S Balkow, S Schimmer, K Schepers, MM Simon, U Dittmer
Virology 330 (2), 365-374, 2004
512004
Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34+ Hematopoietic Stem‐Progenitor Cells
MC Gomez‐Puerto, H Folkerts, ATJ Wierenga, K Schepers, JJ Schuringa, ...
Stem Cells 34 (6), 1651-1663, 2016
462016
Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice
IM Stromnes, U Dittmer, TNM Schumacher, K Schepers, RJ Messer, ...
Journal of virology 76 (5), 2225-2232, 2002
422002
Dissection of cytotoxic and helper T cell responses
K Schepers, R Arens, TNM Schumacher
Cellular and Molecular Life Sciences CMLS 62 (23), 2695-2710, 2005
332005
Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease?
W Broekman, PPSJ Khedoe, K Schepers, H Roelofs, J Stolk, PS Hiemstra
Thorax 73 (6), 565-574, 2018
322018
HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice
CS Devignes, Y Aslan, A Brenot, A Devillers, K Schepers, S Fabre, ...
Proceedings of the National Academy of Sciences 115 (5), E992-E1001, 2018
282018
Long-term functionality of TCR-transduced T cells in vivo
M Coccoris, E Swart, MA de Witte, JWJ van Heijst, JBAG Haanen, ...
The Journal of Immunology 180 (10), 6536-6543, 2008
282008
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