The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018 | 392 | 2018 |
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data A Koleti, R Terryn, V Stathias, C Chung, DJ Cooper, JP Turner, D Vidović, ... Nucleic acids research 46 (D1), D558-D566, 2018 | 168 | 2018 |
LINCS Data Portal 2.0: next generation access point for perturbation-response signatures V Stathias, J Turner, A Koleti, D Vidovic, D Cooper, M Fazel-Najafabadi, ... Nucleic acids research 48 (D1), D431-D439, 2020 | 132 | 2020 |
Evolving BioAssay Ontology (BAO): modularization, integration and applications S Abeyruwan, UD Vempati, H Küçük-McGinty, U Visser, A Koleti, A Mir, ... Journal of biomedical semantics 5, 1-22, 2014 | 96 | 2014 |
Metadata standard and data exchange specifications to describe, model, and integrate complex and diverse high-throughput screening data from the library of integrated network … UD Vempati, C Chung, C Mader, A Koleti, N Datar, D Vidović, D Wrobel, ... Journal of biomolecular screening 19 (5), 803-816, 2014 | 83 | 2014 |
Drug target ontology to classify and integrate drug discovery data Y Lin, S Mehta, H Küçük-McGinty, JP Turner, D Vidovic, M Forlin, A Koleti, ... Journal of biomedical semantics 8, 1-16, 2017 | 75 | 2017 |
Formalization, annotation and analysis of diverse drug and probe screening assay datasets using the BioAssay Ontology (BAO) UD Vempati, MJ Przydzial, C Chung, S Abeyruwan, A Mir, K Sakurai, ... PloS one 7 (11), e49198, 2012 | 65 | 2012 |
Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho … T Schröter, D Minond, A Weiser, C Dao, J Habel, T Spicer, P Chase, ... SLAS Discovery 13 (1), 17-28, 2008 | 55 | 2008 |
Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase Y Xie, Y Liu, G Gong, A Rinderspacher, SX Deng, DH Smith, U Toebben, ... Bioorganic & medicinal chemistry letters 18 (9), 2840-2844, 2008 | 49 | 2008 |
Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids T Vang, Y Xie, WH Liu, D Vidović, Y Liu, S Wu, DH Smith, ... Journal of medicinal chemistry 54 (2), 562-571, 2011 | 41 | 2011 |
Discovery of potent non-urea inhibitors of soluble epoxide hydrolase Y Xie, Y Liu, G Gong, DH Smith, F Yan, A Rinderspacher, Y Feng, Z Zhu, ... Bioorganic & medicinal chemistry letters 19 (8), 2354-2359, 2009 | 35 | 2009 |
Identification of N-(quinolin-8-yl) benzenesulfonamides as agents capable of down-regulating NFκB activity within two separate high-throughput screens of NFκB activation Y Xie, SX Deng, CJ Thomas, Y Liu, YQ Zhang, A Rinderspacher, ... Bioorganic & medicinal chemistry letters 18 (1), 329-335, 2008 | 31 | 2008 |
Sustainable data and metadata management at the BD2K-LINCS Data Coordination and Integration Center V Stathias, A Koleti, D Vidović, DJ Cooper, KM Jagodnik, R Terryn, ... Scientific data 5 (1), 1-14, 2018 | 28 | 2018 |
Potent inhibitors of Huntingtin protein aggregation in a cell-based assay A Rinderspacher, ML Cremona, Y Liu, SX Deng, Y Xie, G Gong, N Aulner, ... Bioorganic & medicinal chemistry letters 19 (6), 1715-1717, 2009 | 17 | 2009 |
Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses E Ong, J Xie, Z Ni, Q Liu, S Sarntivijai, Y Lin, D Cooper, R Terryn, ... BMC bioinformatics 18, 43-53, 2017 | 14 | 2017 |
Discovery of novel small molecule cell type-specific enhancers of NF-κB nuclear translocation G Gong, Y Xie, Y Liu, A Rinderspacher, SX Deng, Y Feng, Z Zhu, Y Tang, ... Bioorganic & medicinal chemistry letters 19 (4), 1191-1194, 2009 | 9 | 2009 |
BAOSearch: a semantic web application for biological screening and drug discovery research S Abeyruwan, C Chung, N Datar, F Gayanilo, A Koleti, V Lemmon, ... Semantic Web Challenge, 9th International Semantic Web Conference (ISWC), 2010 | 4 | 2010 |
Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype D Vidović, Y Xie, A Rinderspacher, SX Deng, DW Landry, C Chung, ... Journal of computer-aided molecular design 25, 873-883, 2011 | 2 | 2011 |
Bioassay Ontology to Describe High-Throughput Screening Assays and their Results. U Vempati, U Visser, S Abeyruwan, K Sakurai, M Przydzial, C Chung, ... ICBO, 2011 | 2 | 2011 |
FAIR LINCS Data and Metadata powered by the CEDAR Framework A Koleti, RS Gonçalves, V Stathias, M Forlin, W Niu, C Monteiro, ... figshare, 2016 | | 2016 |