Claus-Michael Lehr
Claus-Michael Lehr
Helmholtz Inst. Pharm. Research Saarland (HIPS)
Adresse e-mail validée de helmholtz-hzi.de
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In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers
CM Lehr, JA Bouwstra, EH Schacht, HE Junginger
Int. J. Pharm 78 (1), 43-48, 1992
11181992
Preparation and characterization of cationic PLGA nanospheres as DNA carriers
MNVR Kumar, U Bakowsky, CM Lehr
Biomaterials 25 (10), 1771-1777, 2004
5742004
Nanoparticles–an efficient carrier for drug delivery into the hair follicles
J Lademann, H Richter, A Teichmann, N Otberg, U Blume-Peytavi, ...
European Journal of Pharmaceutics and Biopharmaceutics 66 (2), 159-164, 2007
5022007
Size-dependent bioadhesion of micro-and nanoparticulate carriers to the inflamed colonic mucosa
A Lamprecht, U Schäfer, CM Lehr
Pharmaceutical research 18 (6), 788-793, 2001
4502001
Lectin-mediated drug targeting: history and applications
C Bies, CM Lehr, JF Woodley
Advanced drug delivery reviews 56 (4), 425-435, 2004
4392004
The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: Effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro
G Borchard, HL Lueβen, AG de Boer, JC Verhoef, CM Lehr, HE Junginger
Journal of Controlled Release 39 (2-3), 131-138, 1996
4331996
Diverse applications of nanomedicine
B Pelaz, C Alexiou, RA Alvarez-Puebla, F Alves, AM Andrews, S Ashraf, ...
Acs Nano 11 (3), 2313-2381, 2017
4092017
Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease
ALF Lamprecht, N Ubrich, H Yamamoto, U Schäfer, H Takeuchi, ...
Journal of Pharmacology and Experimental Therapeutics 299 (2), 775-781, 2001
3972001
A nonviral DNA delivery system based on surface modified silica-nanoparticles can efficiently transfect cells in vitro
C Kneuer, M Sameti, U Bakowsky, T Schiestel, H Schirra, H Schmidt, ...
Bioconjugate Chemistry 11 (6), 926-932, 2000
3942000
Silica nanoparticles modified with aminosilanes as carriers for plasmid DNA
C Kneuer, M Sameti, EG Haltner, T Schiestel, H Schirra, H Schmidt, ...
International journal of pharmaceutics 196 (2), 257-261, 2000
3682000
Lectin-mediated drug delivery:: The second generation of bioadhesives
CM Lehr
Journal of Controlled Release 65 (1-2), 19-29, 2000
3492000
The human epidermis models EpiSkin®, SkinEthic® and EpiDerm®: an evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance …
F Netzlaff, CM Lehr, PW Wertz, UF Schaefer
European Journal of Pharmaceutics and Biopharmaceutics 60 (2), 167-178, 2005
2842005
Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration
WS Cho, BC Kang, JK Lee, J Jeong, JH Che, SH Seok
Particle and fibre toxicology 10 (1), 9, 2013
2712013
Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: effect of the formulation parameters on complexation and transfection of antisense oligonucleotides
N Nafee, S Taetz, M Schneider, UF Schaefer, CM Lehr
Nanomedicine: Nanotechnology, Biology and Medicine 3 (3), 173-183, 2007
2702007
Intestinal transit of bioadhesive microspheres in an in situ loop in the rat—a comparative study with copolymers and blends based on poly (acrylic acid)
CM Lehr, JA Bouwstra, JJ Tukker, HE Junginger
Journal of Controlled Release 13 (1), 51-62, 1990
2441990
Mechanism of inhibition of P-glycoprotein mediated efflux by vitamin E TPGS: influence on ATPase activity and membrane fluidity
EM Collnot, C Baldes, MF Wempe, R Kappl, J Hüttermann, JA Hyatt, ...
Molecular pharmaceutics 4 (3), 465-474, 2007
2362007
Nanoparticles made from novel starch derivatives for transdermal drug delivery
MJ Santander-Ortega, T Stauner, B Loretz, JL Ortega-Vinuesa, ...
Journal of controlled release 141 (1), 85-92, 2010
2292010
Cationic solid-lipid nanoparticles can efficiently bind and transfect plasmid DNA
C Olbrich, U Bakowsky, CM Lehr, RH Müller, C Kneuer
Journal of controlled release 77 (3), 345-355, 2001
2262001
An estimate of turnover time of intestinal mucus gel layer in the rat in situ loop
CM Lehr, FGJ Poelma, HE Junginger, JJ Tukker
International journal of pharmaceutics 70 (3), 235-240, 1991
2221991
Nanoparticle geometry and surface orientation influence mode of cellular uptake
H Herd, N Daum, AT Jones, H Huwer, H Ghandehari, CM Lehr
ACS nano 7 (3), 1961-1973, 2013
2212013
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