| A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ... Cell reports 17 (4), 1193-1205, 2016 | 633 | 2016 |
| Gene family analysis of the Arabidopsis pollen transcriptome reveals biological implications for cell growth, division control, and gene expression regulation C Pina, F Pinto, JA Feijó, JD Becker Plant physiology 138 (2), 744-756, 2005 | 537 | 2005 |
| Transition states and cell fate decisions in epigenetic landscapes N Moris, C Pina, AM Arias Nature Reviews Genetics 17 (11), 693-703, 2016 | 400 | 2016 |
| Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level G Swiers, C Baumann, J O’Rourke, E Giannoulatou, S Taylor, A Joshi, ... Nature communications 4 (1), 2924, 2013 | 200 | 2013 |
| Inferring rules of lineage commitment in haematopoiesis C Pina, C Fugazza, AJ Tipping, J Brown, S Soneji, J Teles, C Peterson, ... Nature cell biology 14 (3), 287-294, 2012 | 196 | 2012 |
| High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle AJ Tipping, C Pina, A Castor, D Hong, NP Rodrigues, L Lazzari, GE May, ... Blood, The Journal of the American Society of Hematology 113 (12), 2661-2672, 2009 | 148 | 2009 |
| Chromosomal G-dark bands determine the spatial organization of centromeric heterochromatin in the nucleus C Carvalho, HM Pereira, J Ferreira, C Pina, D Mendonça, AC Rosa, ... Molecular biology of the cell 12 (11), 3563-3572, 2001 | 98 | 2001 |
| Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors G May, S Soneji, AJ Tipping, J Teles, SJ McGowan, M Wu, Y Guo, ... Cell stem cell 13 (6), 754-768, 2013 | 94 | 2013 |
| Generation of bivalent chromatin domains during cell fate decisions M De Gobbi, D Garrick, M Lynch, D Vernimmen, JR Hughes, N Goardon, ... Epigenetics & chromatin 4, 1-12, 2011 | 79 | 2011 |
| MLLT3 regulates early human erythroid and megakaryocytic cell fate C Pina, G May, S Soneji, D Hong, T Enver Cell stem cell 2 (3), 264-273, 2008 | 79 | 2008 |
| Single-cell network analysis identifies DDIT3 as a nodal lineage regulator in hematopoiesis C Pina, J Teles, C Fugazza, G May, D Wang, Y Guo, S Soneji, J Brown, ... Cell reports 11 (10), 1503-1510, 2015 | 77 | 2015 |
| SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 K Tzelepis, E De Braekeleer, D Aspris, I Barbieri, MS Vijayabaskar, ... Nature communications 9 (1), 5378, 2018 | 65 | 2018 |
| The tetraspanin CD9 affords high-purity capture of all murine hematopoietic stem cells G Karlsson, E Rörby, C Pina, S Soneji, K Reckzeh, K Miharada, ... Cell reports 4 (4), 642-648, 2013 | 59 | 2013 |
| Transcriptional regulation of lineage commitment-a stochastic model of cell fate decisions J Teles, C Pina, P Edén, M Ohlsson, T Enver, C Peterson PLoS computational biology 9 (8), e1003197, 2013 | 56 | 2013 |
| Differential contributions of haematopoietic stem cells to foetal and adult haematopoiesis: insights from functional analysis of transcriptional regulators C Pina, T Enver Oncogene 26 (47), 6750-6765, 2007 | 45 | 2007 |
| Histone acetyltransferase KAT2A stabilizes pluripotency with control of transcriptional heterogeneity N Moris, S Edri, D Seyres, R Kulkarni, AF Domingues, T Balayo, ... Stem Cells 36 (12), 1828-1838, 2018 | 40 | 2018 |
| Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells AF Domingues, R Kulkarni, G Giotopoulos, S Gupta, L Vinnenberg, ... Elife 9, e51754, 2020 | 31 | 2020 |
| A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia. Cell Rep. 17, 1193–1205 K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ... J. CELREP 79, 2016 | 29 | 2016 |
| Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions C Erady, A Boxall, S Puntambekar, N Suhas Jagannathan, R Chauhan, ... NPJ genomic medicine 6 (1), 4, 2021 | 25 | 2021 |
| Long non-coding RNAs as functional and structural chromatin modulators in acute myeloid leukemia AA Wurm, C Pina Frontiers in oncology 9, 899, 2019 | 20 | 2019 |
