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Shuyuan Chen
Shuyuan Chen
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Echocardiographic destruction of albumin microbubbles directs gene delivery to the myocardium
RV Shohet, S Chen, YT Zhou, Z Wang, RS Meidell, RH Unger, ...
Circulation 101 (22), 2554-2556, 2000
6432000
Ultrasound-targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart
R Bekeredjian, S Chen, PA Frenkel, PA Grayburn, RV Shohet
Circulation 108 (8), 1022-1026, 2003
4362003
Optimization of ultrasound parameters for cardiac gene delivery of adenoviral or plasmid deoxyribonucleic acid by ultrasound-targeted microbubble destruction
S Chen, RV Shohet, R Bekeredjian, P Frenkel, PA Grayburn
Journal of the American College of Cardiology 42 (2), 301-308, 2003
2902003
Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technology
S Chen, J Ding, R Bekeredjian, B Yang, RV Shohet, SA Johnston, ...
Proceedings of the National Academy of Sciences 103 (22), 8469-8474, 2006
2472006
DNA-loaded albumin microbubbles enhance ultrasound-mediated transfection in vitro
PA Frenkel, S Chen, T Thai, RV Shohet, PA Grayburn
Ultrasound in medicine & biology 28 (6), 817-822, 2002
2342002
Targeting of VEGF-mediated angiogenesis to rat myocardium using ultrasonic destruction of microbubbles
G Korpanty, S Chen, RV Shohet, J Ding, B Yang, PA Frenkel, ...
Gene therapy 12 (17), 1305-1312, 2005
1882005
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome
MY Wang, P Grayburn, S Chen, M Ravazzola, L Orci, RH Unger
Proceedings of the National Academy of Sciences 105 (16), 6139-6144, 2008
1712008
Augmentation of cardiac protein delivery using ultrasound targeted microbubble destruction
R Bekeredjian, S Chen, PA Grayburn, RV Shohet
Ultrasound in medicine & biology 31 (5), 687-691, 2005
1272005
Bioeffects of myocardial contrast microbubble destruction by echocardiography
S Chen, MH Kroll, RV Shohet, P Frenkel, SA Mayer, PA Grayburn
Echocardiography 19 (6), 495-500, 2002
932002
Mannose receptor-mediated delivery of moss-made α-galactosidase A efficiently corrects enzyme deficiency in Fabry mice
JS Shen, A Busch, TS Day, XL Meng, CI Yu, P Dabrowska-Schlepp, ...
Journal of inherited metabolic disease 39, 293-303, 2016
882016
Regeneration of pancreatic islets in vivo by ultrasound-targeted gene therapy
S Chen, M Shimoda, MY Wang, J Ding, H Noguchi, S Matsumoto, ...
Gene therapy 17 (11), 1411-1420, 2010
752010
Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pancreatic duodenal homeobox-1
S Chen, J Ding, C Yu, B Yang, DR Wood, PA Grayburn
Gene therapy 14 (14), 1102-1110, 2007
702007
Gene or drug delivery system
P Grayburn, C Shuyuan
US Patent App. 11/198,210, 2007
662007
In vivo non-viral gene delivery of human vascular endothelial growth factor improves revascularisation and restoration of euglycaemia after human islet transplantation into …
M Shimoda, S Chen, H Noguchi, S Matsumoto, PA Grayburn
Diabetologia 53, 1669-1679, 2010
612010
Effects of ultrasound-targeted microbubble destruction on cardiac gene expression
R Bekeredjian, S Chen, W Pan, PA Grayburn, RV Shohet
Ultrasound in medicine & biology 30 (4), 539-543, 2004
562004
Transient overexpression of cyclin D2/CDK4/GLP1 genes induces proliferation and differentiation of adult pancreatic progenitors and mediates islet regeneration
S Chen, M Shimoda, J Chen, S Matsumoto, PA Grayburn
Cell Cycle 11 (4), 695-705, 2012
502012
Stimulation of adult resident cardiac progenitor cells by durable myocardial expression of thymosin beta 4 with ultrasound-targeted microbubble delivery
S Chen, M Shimoda, J Chen, PA Grayburn
Gene therapy 20 (2), 225-233, 2013
492013
In vivo targeted delivery of ANGPTL8 gene for beta cell regeneration in rats
J Chen, S Chen, P Huang, XL Meng, S Clayton, JS Shen, PA Grayburn
Diabetologia 58, 1036-1044, 2015
462015
Anti-tumor efficacy of ultrasonic cavitation is potentiated by concurrent delivery of anti-angiogenic drug in colon cancer
C Zhang, P Huang, Y Zhang, J Chen, W Shentu, Y Sun, Z Yang, S Chen
Cancer Letters 347 (1), 105-113, 2014
462014
Successful β cells islet regeneration in streptozotocin-induced diabetic baboons using ultrasound-targeted microbubble gene therapy with cyclinD2/CDK4/GLP1
S Chen, RA Bastarrachea, BJ Roberts, VS Voruganti, PA Frost, ...
Cell Cycle 13 (7), 1145-1151, 2014
442014
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