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Shilpa Sampathi
Shilpa Sampathi
Adresse e-mail validée de uky.edu
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Mammalian DNA2 helicase/nuclease cleaves G‐quadruplex DNA and is required for telomere integrity
W Lin, S Sampathi, H Dai, C Liu, M Zhou, J Hu, Q Huang, J Campbell, ...
The EMBO journal 32 (10), 1425-1439, 2013
1772013
HDAC3 is essential for DNA replication in hematopoietic progenitor cells
AR Summers, MA Fischer, KR Stengel, Y Zhao, JF Kaiser, CE Wells, ...
The Journal of clinical investigation 123 (7), 3112-3123, 2013
902013
Molecular steps of G‐overhang generation at human telomeres and its function in chromosome end protection
X Dai, C Huang, A Bhusari, S Sampathi, K Schubert, W Chai
The EMBO journal 29 (16), 2788-2801, 2010
852010
The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5′ and 3′ ends of genes
S Sampathi, P Acharya, Y Zhao, J Wang, KR Stengel, Q Liu, MR Savona, ...
Nucleic acids research 47 (8), 3921-3936, 2019
392019
Telomere replication: poised but puzzling
S Sampathi, W Chai
Journal of cellular and molecular medicine 15 (1), 3-13, 2011
392011
Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance
S Sampathi, A Bhusari, B Shen, W Chai
Journal of biological chemistry 284 (6), 3682-3690, 2009
392009
Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia
G Johnston, HE Ramsey, Q Liu, J Wang, KR Stengel, S Sampathi, ...
Gene 752, 144758, 2020
212020
Histone deacetylase 3 controls a transcriptional network required for B cell maturation
KR Stengel, S Bhaskara, J Wang, Q Liu, JD Ellis, S Sampathi, SW Hiebert
Nucleic acids research 47 (20), 10612-10627, 2019
172019
A screen of FDA-approved drugs identifies inhibitors of protein tyrosine phosphatase 4A3 (PTP4A3 or PRL-3)
DR Rivas, MVC Dela Cerna, CN Smith, S Sampathi, BG Patty, D Lee, ...
Scientific Reports 11 (1), 10302, 2021
62021
Mapping the FEN1 interaction domain with hTERT
S Sampathi, W Chai
Biochemical and biophysical research communications 407 (1), 34-38, 2011
42011
Nanopore sequencing of clonal IGH rearrangements in cell-free DNA as a biomarker for acute lymphoblastic leukemia
S Sampathi, Y Chernyavskaya, MG Haney, LH Moore, IA Snyder, AH Cox, ...
Frontiers in Oncology 12, 958673, 2022
32022
Mtg16-dependent repression of E protein activity is required for early lymphopoiesis
P Acharya, S Sampathi, DK Flaherty, BK Matlock, CS Williams, ...
Biorxiv, 2020.07. 24.220525, 2020
22020
Histone deacetylase inhibitors mimic BET inhibitors and cause RNA polymerase pausing at MYC, KIT, and other oncogenes in t (8; 21) AML
P Acharya, S Sampathi, Y Zhao, J Wang, Q Liu, K Stengel, S Hiebert
Blood 130 (Supplement 1), 2470-2470, 2017
22017
Extracellular vesicle mediated radioresistance in H3K27M-diffuse midline glioma
V Oza, S Sampathi, Y Chernyavskava, K Flores, J Blackburn
Cancer Research 84 (6_Supplement), 1126-1126, 2024
2024
Zebrafish drug screening identifies Erlotinib as an inhibitor of Wnt/β-catenin signaling and self-renewal in T-cell acute lymphoblastic leukemia
MA Al-Hamaly, AH Cox, MG Haney, W Zhang, EC Arvin, S Sampathi, ...
Biomedicine & Pharmacotherapy 170, 116013, 2024
2024
Novel methods to assess cell-free circulating tumor DNA in acute lymphoblastic leukemia.
MG Haney, S Sampathi, Y Chernyavskaya, H Moore, TC Badgett, ...
Journal of Clinical Oncology 39 (15_suppl), 10034-10034, 2021
2021
Nanopore sequencing methods detect cell-free DNA associated with minimal residual disease and central nervous system infiltration in pediatric Acute Lymphoblastic Leukemia
S Sampathi, Y Chernyavskaya, MG Haney, LH Moore, IA Snyder, AH Cox, ...
bioRxiv, 2021
2021
Cell-Free DNA As a Biomarker for Acute Lymphoblastic Leukemia Relapse in the Central Nervous System
M Haney, H Moore, S Sampathi, Y Chernyavskaya, T Badgett, ...
Blood 136, 7-8, 2020
2020
Nascent Transcript and Single Cell Rnaseq Analysis Defines the Mechanism of Action of the LSD1 Inhibitor INCB059872 in Myeloid Leukemia
G Johnston, HE Ramsey, K Stengel, S Sampathi, P Acharya, M Arrate, ...
Blood 134, 2509, 2019
2019
New Insights into the roles of DNA replication/repair proteins at telomeres
S Sampathi
Washington State University, 2011
2011
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