A recent bottleneck of Y chromosome diversity coincides with a global change in culture M Karmin, L Saag, M Vicente, MA Wilson Sayres, M Järve, UG Talas, ... Genome Research 25, 459-466, 2015 | 506 | 2015 |
Genomic analyses inform on migration events during the peopling of Eurasia L Pagani, DJ Lawson, E Jagoda, A Mörseburg, A Eriksson, M Mitt, ... Nature 538 (7624), 238-242, 2016 | 483 | 2016 |
SNP ascertainment bias in population genetic analyses: why it is important, and how to correct it J Lachance, SA Tishkoff Bioessays 35 (9), 780-786, 2013 | 369 | 2013 |
Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers J Lachance, B Vernot, CC Elbers, B Ferwerda, A Froment, JM Bodo, ... Cell 150 (3), 457-469, 2012 | 366 | 2012 |
The genetic prehistory of southern Africa JK Pickrell, N Patterson, C Barbieri, F Berthold, L Gerlach, T Güldemann, ... Nature Communications 3, 1143, 2012 | 328 | 2012 |
Genetic disease risks can be misestimated across global populations MS Kim, KP Patel, AK Teng, AJ Berens, J Lachance Genome biology 19, 1-14, 2018 | 198 | 2018 |
Phylogeny estimation by integration over isolation with migration models J Hey, Y Chung, A Sethuraman, J Lachance, S Tishkoff, VC Sousa, ... Molecular biology and evolution 35 (11), 2805-2818, 2018 | 128 | 2018 |
Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies. PH Hsieh, AE Woerner, JD Wall, J Lachance, SA Tishkoff, RN Gutenkunst, ... Genome Research 26 (3), 291, 2016 | 123 | 2016 |
The genetics of sex chromosomes: evolution and implications for hybrid incompatibility NA Johnson, J Lachance Annals of the New York Academy of Sciences 1256 (1), E1-E22, 2012 | 113 | 2012 |
Population genomics of human adaptation J Lachance, SA Tishkoff Annual Review of Ecology, Evolution, and Systematics 44 (1), 123-143, 2013 | 105 | 2013 |
Biased gene conversion skews allele frequencies in human populations, increasing the disease burden of recessive alleles J Lachance, SA Tishkoff The American Journal of Human Genetics 95 (4), 408-420, 2014 | 69 | 2014 |
Whole genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection PH Hsieh, KR Veeramah, J Lachance, SA Tishkoff, JD Wall, MF Hammer, ... Genome Research 26 (3), 279, 2016 | 68 | 2016 |
Genetic hitchhiking and population bottlenecks contribute to prostate cancer disparities in men of African descent J Lachance, AJ Berens, MEB Hansen, AK Teng, SA Tishkoff, TR Rebbeck Cancer research 78 (9), 2432-2443, 2018 | 65 | 2018 |
Apparent variation in Neanderthal admixture among African populations is consistent with gene flow from non-African populations S Wang, J Lachance, SA Tishkoff, J Hey, J Xing Genome biology and evolution 5 (11), 2075-2081, 2013 | 47 | 2013 |
Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations J Lachance BMC medical genomics 3 (1), 57, 2010 | 38 | 2010 |
Evidence for positive selection on recent human transposable element insertions L Rishishwar, L Wang, J Wang, VY Soojin, J Lachance, IK Jordan Gene 675, 69-79, 2018 | 37 | 2018 |
The genomic health of ancient hominins AJ Berens, TL Cooper, J Lachance Human biology 89 (1), 7-19, 2017 | 36 | 2017 |
Long-term adaptation of epistatic genetic networks R Yukilevich, J Lachance, F Aoki, JR True Evolution 62 (9), 2215-2235, 2008 | 36 | 2008 |
X‐autosome incompatibilities in Drosophila melanogaster: tests of Haldane's rule and geographical patterns within species J Lachance, JR True Evolution 64 (10), 3035-3046, 2010 | 34 | 2010 |
Detecting selection-induced departures from Hardy-Weinberg proportions J Lachance Genetics Selection Evolution 41, 1-6, 2009 | 33 | 2009 |