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Becht Etienne
Becht Etienne
Ligue Nationale Contre le Cancer
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Dimensionality reduction for visualizing single-cell data using UMAP
E Becht, L McInnes, J Healy, CA Dutertre, IWH Kwok, LG Ng, F Ginhoux, ...
Nature Biotechnology, 2018
22242018
Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression
E Becht, NA Giraldo, L Lacroix, B Buttard, N Elarouci, F Petitprez, J Selves, ...
Genome biology 17 (1), 1-20, 2016
11272016
Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates
Y Simoni, E Becht, M Fehlings, CY Loh, SL Koo, KWW Teng, JPS Yeong, ...
Nature 557 (7706), 575-579, 2018
7062018
Presence of B cells in tertiary lymphoid structures is associated with a protective immunity in patients with lung cancer
C Germain, S Gnjatic, F Tamzalit, S Knockaert, R Remark, J Goc, ...
American journal of respiratory and critical care medicine 189 (7), 832-844, 2014
4432014
Immune and stromal classification of colorectal cancer is associated with molecular subtypes and relevant for precision immunotherapy
E Becht, A de Reyniès, NA Giraldo, C Pilati, B Buttard, L Lacroix, J Selves, ...
Clinical cancer research 22 (16), 4057-4066, 2016
4152016
Dendritic cells in tumor-associated tertiary lymphoid structures signal a Th1 cytotoxic immune contexture and license the positive prognostic value of infiltrating CD8+ T cells
J Goc, C Germain, TKD Vo-Bourgais, A Lupo, C Klein, S Knockaert, ...
Cancer research 74 (3), 705-715, 2014
3932014
Orchestration and prognostic significance of immune checkpoints in the microenvironment of primary and metastatic renal cell cancer
NA Giraldo, E Becht, F Pagès, G Skliris, V Verkarre, Y Vano, A Mejean, ...
Clinical Cancer Research 21 (13), 3031-3040, 2015
3152015
Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions
M Evrard, IWH Kwok, SZ Chong, KWW Teng, E Becht, J Chen, JL Sieow, ...
Immunity 48 (2), 364-379. e8, 2018
3142018
Orchestrating single-cell analysis with Bioconductor
RA Amezquita, ATL Lun, E Becht, VJ Carey, LN Carpp, L Geistlinger, ...
Nature methods 17 (2), 137-145, 2020
2702020
Cancer stemness, intratumoral heterogeneity, and immune response across cancers
A Miranda, PT Hamilton, AW Zhang, S Pattnaik, E Becht, A Mezheyeuski, ...
Proceedings of the National Academy of Sciences, 201818210, 2019
2172019
The clinical role of the TME in solid cancer
NA Giraldo, R Sanchez-Salas, JD Peske, Y Vano, E Becht, F Petitprez, ...
British journal of cancer 120 (1), 45-53, 2019
2152019
Molecular subtypes of clear cell renal cell carcinoma are associated with sunitinib response in the metastatic setting
B Beuselinck, S Job, E Becht, A Karadimou, V Verkarre, G Couchy, ...
Clinical cancer research 21 (6), 1329-1339, 2015
2132015
Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells
CA Dutertre, E Becht, SE Irac, A Khalilnezhad, V Narang, S Khalilnezhad, ...
Immunity 51 (3), 573-589. e8, 2019
2122019
Tumor-infiltrating and peripheral blood T-cell immunophenotypes predict early relapse in localized clear cell renal cell carcinoma
NA Giraldo, E Becht, Y Vano, F Petitprez, L Lacroix, P Validire, ...
Clinical Cancer Research 23 (15), 4416-4428, 2017
2012017
Chapter Four-Immune Contexture, Immunoscore, and Malignant Cell Molecular Subgroups for Prognostic and Theranostic Classifications of Cancers
E Becht, NA Giraldo, C Germain, A de Reyniès, P Laurent-Puig, ...
Advances in Immunology 130, 95-190, 2016
161*2016
Hepatitis B virus–specific T cells associate with viral control upon nucleos (t) ide-analogue therapy discontinuation
L Rivino, N Le Bert, US Gill, K Kunasegaran, Y Cheng, DZM Tan, E Becht, ...
The Journal of clinical investigation 128 (2), 668-681, 2018
1472018
Calreticulin Expression in Human Non–Small Cell Lung Cancers Correlates with Increased Accumulation of Antitumor Immune Cells and Favorable Prognosis
J Fucikova, E Becht, K Iribarren, J Goc, R Remark, D Damotte, M Alifano, ...
Cancer research 76 (7), 1746-1756, 2016
1362016
Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage
RJ Dress, CA Dutertre, A Giladi, A Schlitzer, I Low, NB Shadan, A Tay, ...
Nature Immunology 20 (7), 852-864, 2019
1342019
Cancer immune contexture and immunotherapy
E Becht, NA Giraldo, MC Dieu-Nosjean, C Sautès-Fridman, WH Fridman
Current opinion in immunology 39, 7-13, 2016
1342016
Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer
M Podrazil, R Horvath, E Becht, D Rozkova, P Bilkova, K Sochorova, ...
Oncotarget 6 (20), 18192, 2015
1252015
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