K.C. Allen Chan
K.C. Allen Chan
Adresse e-mail validée de cuhk.edu.hk
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Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma
RWK Chiu, KCA Chan, Y Gao, VYM Lau, W Zheng, TY Leung, CHF Foo, ...
Proceedings of the National Academy of Sciences 105 (51), 20458-20463, 2008
10802008
Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study
RWK Chiu, R Akolekar, YWL Zheng, TY Leung, H Sun, KCA Chan, ...
Bmj 342, c7401, 2011
9412011
Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus
YMD Lo, KCA Chan, H Sun, EZ Chen, P Jiang, FMF Lun, YW Zheng, ...
Science translational medicine 2 (61), 61ra91-61ra91, 2010
9202010
Size distributions of maternal and fetal DNA in maternal plasma
KCA Chan, J Zhang, ABY Hui, N Wong, TK Lau, TN Leung, KW Lo, ...
Clinical chemistry 50 (1), 88-92, 2004
7432004
Digital PCR for the molecular detection of fetal chromosomal aneuploidy
YMD Lo, FMF Lun, KCA Chan, NBY Tsui, KC Chong, TK Lau, TY Leung, ...
Proceedings of the National Academy of Sciences 104 (32), 13116-13121, 2007
5692007
Microfluidics digital PCR reveals a higher than expected fraction of fetal DNA in maternal plasma
FMF Lun, RWK Chiu, KC Allen Chan, T Yeung Leung, T Kin Lau, ...
Clinical chemistry 54 (10), 1664-1672, 2008
5162008
Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection
IFN Hung, KKW To, CK Lee, KL Lee, K Chan, WW Yan, R Liu, CL Watt, ...
Clinical Infectious Diseases 52 (4), 447-456, 2011
4892011
Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non–small cell lung cancer patients
TKF Yung, KCA Chan, TSK Mok, J Tong, KF To, YMD Lo
Clinical Cancer Research 15 (6), 2076-2084, 2009
4412009
Cancer genome scanning in plasma: detection of tumor-associated copy number aberrations, single-nucleotide variants, and tumoral heterogeneity by massively parallel sequencing
KCA Chan, P Jiang, YWL Zheng, GJW Liao, H Sun, J Wong, SSN Siu, ...
Clinical chemistry 59 (1), 211-224, 2013
4372013
Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients
N Lee, KCA Chan, DS Hui, EKO Ng, A Wu, RWK Chiu, VWS Wong, ...
Journal of clinical virology 31 (4), 304-309, 2004
4212004
Hypermethylated RASSF1A in Maternal Plasma: A Universal Fetal DNA Marker that Improves the Reliability of Noninvasive Prenatal Diagnosis
KCA Chan, C Ding, A Gerovassili, SW Yeung, RWK Chiu, TN Leung, ...
Clinical chemistry 52 (12), 2211-2218, 2006
4022006
Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing
EZ Chen, RWK Chiu, H Sun, R Akolekar, KCA Chan, TY Leung, P Jiang, ...
PloS one 6 (7), e21791, 2011
4002011
Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma
FMF Lun, NBY Tsui, KCA Chan, TY Leung, TK Lau, P Charoenkwan, ...
Proceedings of the National Academy of Sciences 105 (50), 19920-19925, 2008
3912008
Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients
P Jiang, CWM Chan, KCA Chan, SH Cheng, J Wong, VWS Wong, ...
Proceedings of the National Academy of Sciences 112 (11), E1317-E1325, 2015
3682015
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
K Sun, P Jiang, KCA Chan, J Wong, YKY Cheng, RHS Liang, W Chan, ...
Proceedings of the National Academy of Sciences 112 (40), E5503-E5512, 2015
3492015
Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma
S Leung, B Zee, BB Ma, EP Hui, F Mo, M Lai, KCA Chan, LYS Chan, ...
Journal of clinical oncology 24 (34), 5414-5418, 2006
2932006
Analysis of plasma Epstein–Barr virus DNA to screen for nasopharyngeal cancer
KCA Chan, JKS Woo, A King, BCY Zee, WKJ Lam, SL Chan, SWI Chu, ...
New England Journal of Medicine 377 (6), 513-522, 2017
2882017
Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing
KCA Chan, P Jiang, CWM Chan, K Sun, J Wong, EP Hui, SL Chan, ...
Proceedings of the National Academy of Sciences 110 (47), 18761-18768, 2013
2702013
Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA
NBY Tsui, RA Kadir, KC Chan, C Chi, G Mellars, EG Tuddenham, ...
Blood 117 (13), 3684-3691, 2011
2462011
Molecular characterization of circulating EBV DNA in the plasma of nasopharyngeal carcinoma and lymphoma patients
KCA Chan, J Zhang, ATC Chan, KIK Lei, SF Leung, LYS Chan, ...
Cancer research 63 (9), 2028-2032, 2003
2362003
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