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Pierre Bruhns
Pierre Bruhns
Institut Pasteur
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Specificity and affinity of human Fcγ receptors and their polymorphic variants for human IgG subclasses
P Bruhns, B Iannascoli, P England, DA Mancardi, N Fernandez, S Jorieux, ...
Blood, The Journal of the American Society of Hematology 113 (16), 3716-3725, 2009
16522009
Properties of mouse and human IgG receptors and their contribution to disease models
P Bruhns
Blood, The Journal of the American Society of Hematology 119 (24), 5640-5649, 2012
9602012
FcγRIV: a novel FcR with distinct IgG subclass specificity
F Nimmerjahn, P Bruhns, K Horiuchi, JV Ravetch
Immunity 23 (1), 41-51, 2005
8802005
The function of Fcγ receptors in dendritic cells and macrophages
M Guilliams, P Bruhns, Y Saeys, H Hammad, BN Lambrecht
Nature Reviews Immunology 14 (2), 94-108, 2014
7202014
Mouse and human FcR effector functions
P Bruhns, F Jönsson
Immunological reviews 268 (1), 25-51, 2015
5042015
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
4422021
Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease
P Bruhns, A Samuelsson, JW Pollard, JV Ravetch
Immunity 18 (4), 573-581, 2003
3722003
Mouse and human neutrophils induce anaphylaxis
F Jönsson, DA Mancardi, Y Kita, H Karasuyama, B Iannascoli, ...
The Journal of clinical investigation 121 (4), 1484-1496, 2011
3282011
The RasGAP-binding protein p62dok is a mediator of inhibitory FcγRIIB signals in B cells
I Tamir, JC Stolpa, CD Helgason, K Nakamura, P Bruhns, M Daeron, ...
Immunity 12 (3), 347-358, 2000
3242000
Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORγt and LTi cells
M Lochner, C Ohnmacht, L Presley, P Bruhns, M Si-Tahar, S Sawa, ...
Journal of Experimental Medicine 208 (1), 125-134, 2011
2602011
Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia
M Olsson, P Bruhns, WA Frazier, JV Ravetch, PA Oldenborg
Blood 105 (9), 3577-3582, 2005
2242005
Single-cell deep phenotyping of IgG-secreting cells for high-resolution immune monitoring
K Eyer, RCL Doineau, CE Castrillon, L Briseño-Roa, V Menrath, G Mottet, ...
Nature biotechnology 35 (10), 977-982, 2017
2132017
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges
B Piasecka, D Duffy, A Urrutia, H Quach, E Patin, C Posseme, J Bergstedt, ...
Proceedings of the National Academy of Sciences 115 (3), E488-E497, 2018
2032018
High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics
A Gérard, A Woolfe, G Mottet, M Reichen, C Castrillon, V Menrath, ...
Nature biotechnology 38 (6), 715-721, 2020
1952020
The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy
DA Mancardi, M Albanesi, F Jönsson, B Iannascoli, N Van Rooijen, ...
Blood, The Journal of the American Society of Hematology 121 (9), 1563-1573, 2013
1842013
Neutrophils mediate antibody-induced antitumor effects in mice
M Albanesi, DA Mancardi, F Jönsson, B Iannascoli, L Fiette, JP Di Santo, ...
Blood, The Journal of the American Society of Hematology 122 (18), 3160-3164, 2013
1782013
FcγRIV is a mouse IgE receptor that resembles macrophage FcεRI in humans and promotes IgE-induced lung inflammation
DA Mancardi, B Iannascoli, S Hoos, P England, M Daëron, P Bruhns
The Journal of clinical investigation 118 (11), 3738-3750, 2008
1642008
Contribution of human FcγRs to disease with evidence from human polymorphisms and transgenic animal studies
C Gillis, A Gouel-Chéron, F Jönsson, P Bruhns
Frontiers in immunology 5, 89310, 2014
1522014
Human FcγRIIA induces anaphylactic and allergic reactions
F Jönsson, DA Mancardi, W Zhao, Y Kita, B Iannascoli, H Khun, ...
Blood, The Journal of the American Society of Hematology 119 (11), 2533-2544, 2012
1472012
IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions
CH Lee, G Romain, W Yan, M Watanabe, W Charab, B Todorova, J Lee, ...
Nature immunology 18 (8), 889-898, 2017
1352017
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