Kendell Clement
Kendell Clement
Assistant Professor, University of Utah
Verified email at
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CRISPResso2 provides accurate and rapid genome editing sequence analysis
K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ...
Nature biotechnology 37 (3), 224-226, 2019
Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ...
Nature biotechnology 37 (3), 276-282, 2019
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells
J Liao, R Karnik, H Gu, MJ Ziller, K Clement, AM Tsankov, V Akopian, ...
Nature genetics 47 (5), 469-478, 2015
Highly efficient therapeutic gene editing of human hematopoietic stem cells
Y Wu, J Zeng, BP Roscoe, P Liu, Q Yao, CR Lazzarotto, K Clement, ...
Nature medicine 25 (5), 776-783, 2019
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities
JM Gehrke, O Cervantes, MK Clement, Y Wu, J Zeng, DE Bauer, L Pinello, ...
Nature biotechnology 36 (10), 977-982, 2018
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia
DA Landau, K Clement, MJ Ziller, P Boyle, J Fan, H Gu, K Stevenson, ...
Cancer cell 26 (6), 813-825, 2014
In vivo CRISPR editing with no detectable genome-wide off-target mutations
P Akcakaya, ML Bobbin, JA Guo, J Malagon-Lopez, K Clement, SP Garcia, ...
Nature 561 (7723), 416-419, 2018
A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs
J Choi, S Lee, W Mallard, K Clement, GM Tagliazucchi, H Lim, IY Choi, ...
Nature biotechnology 33 (11), 1173-1181, 2015
Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling
P Boyle, K Clement, H Gu, ZD Smith, M Ziller, JL Fostel, L Holmes, ...
Genome biology 13, 1-10, 2012
Assessment of computational methods for the analysis of single-cell ATAC-seq data
H Chen, C Lareau, T Andreani, ME Vinyard, SP Garcia, K Clement, ...
Genome biology 20, 1-25, 2019
Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells
J Choi, AJ Huebner, K Clement, RM Walsh, A Savol, K Lin, H Gu, ...
Nature 548 (7666), 219-223, 2017
Therapeutic base editing of human hematopoietic stem cells
J Zeng, Y Wu, C Ren, J Bonanno, AH Shen, D Shea, JM Gehrke, ...
Nature medicine 26 (4), 535-541, 2020
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia
F Gaiti, R Chaligne, H Gu, RM Brand, S Kothen-Hill, RC Schulman, ...
Nature 569 (7757), 576-580, 2019
Genetic determinants and epigenetic effects of pioneer-factor occupancy
J Donaghey, S Thakurela, J Charlton, JS Chen, ZD Smith, H Gu, R Pop, ...
Nature genetics 50 (2), 250-258, 2018
Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer
ZD Smith, J Shi, H Gu, J Donaghey, K Clement, D Cacchiarelli, A Gnirke, ...
Nature 549 (7673), 543-547, 2017
CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells
K Petri, W Zhang, J Ma, A Schmidts, H Lee, JE Horng, DY Kim, IC Kurt, ...
Nature biotechnology 40 (2), 189-193, 2022
Genome-wide tracking of dCas9-methyltransferase footprints
C Galonska, J Charlton, AL Mattei, J Donaghey, K Clement, H Gu, ...
Nature communications 9 (1), 597, 2018
Cancer-germline antigen expression discriminates clinical outcome to CTLA-4 blockade
SA Shukla, P Bachireddy, B Schilling, C Galonska, Q Zhan, C Bango, ...
Cell 173 (3), 624-633. e8, 2018
Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells
W Li, C Cavelti-Weder, Y Zhang, K Clement, S Donovan, G Gonzalez, ...
Nature biotechnology 32 (12), 1223-1230, 2014
The RNA helicase DDX6 controls cellular plasticity by modulating P-body homeostasis
B Di Stefano, EC Luo, C Haggerty, S Aigner, J Charlton, J Brumbaugh, ...
Cell stem cell 25 (5), 622-638. e13, 2019
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