Myles Brown

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Xiaole Shirley LiuCEO, GV20 TherapeuticsAdresse e-mail validée de ds.dfci.harvard.edu
Cliff MeyerDana-Farber Cancer Institute and Harvard T.H. Chan School of Public HealthAdresse e-mail validée de jimmy.harvard.edu
Jason CarrollUniversity of CambridgeAdresse e-mail validée de cruk.cam.ac.uk
Tengfei XiaoCTO, GV20 OncotherapyAdresse e-mail validée de bioxbh.com
Housheng Hansen HePrincess Margaret Cancer Centre, University Health Network; Department of Medical BiophysicsAdresse e-mail validée de uhnresearch.ca
Wei LiGrace B. Bell Endowed Chair and Professor of Bioinformatics, University of California IrvineAdresse e-mail validée de uci.edu
Tao LiuAssociate Professor, Roswell Park Comprehensive Cancer CenterAdresse e-mail validée de roswellpark.org
Peng JiangStadtman Tenure-Track Investigator, National Cancer Institute, NIHAdresse e-mail validée de nih.gov
Mathieu Lupien, PhD; FRSCSenior Scientist/Professor, Princess Margaret Cancer CentreAdresse e-mail validée de uhn.ca
Shengqing (Stan) GuThe University of Texas MD Anderson Cancer CenterAdresse e-mail validée de mdanderson.org
Qianben Wang, Ph.D.Banks Anderson, Sr. Distinguished Professor of Pathology, Duke University School of MedicineAdresse e-mail validée de duke.edu
Yong Zhang 张勇Professor of Bioinformatics, Tongji UniversityAdresse e-mail validée de tongji.edu.cn
Wei LiAssociate Professor, Children's National Hospital, George Washington UniversityAdresse e-mail validée de childrensnational.org
Elgene LimUNSW, Garvan Institute, St Vincent's HospitalAdresse e-mail validée de garvan.org.au
Xintao QiuHarvard Medical School / Dana Faber Cancer InstituteAdresse e-mail validée de dfci.harvard.edu
Yiwen ChenAssociate Professor at University of Texas MD Anderson Cancer CenterAdresse e-mail validée de mdanderson.org
Rachel SchiffBaylor College of MedicineAdresse e-mail validée de bcm.edu
James DiRenzoCognoscenti ScientificAdresse e-mail validée de dartmouth.edu
Kai WucherpfennigAdresse e-mail validée de dfci.harvard.edu
Gilles BuchwalterDana-Farber Cancer Institute, Harvard Medical SchoolAdresse e-mail validée de dfci.harvard.edu

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Myles Brown

Emil Frei III Professor of Medicine, Dana-Farber Cancer Institute and Harvard Medical School

Adresse e-mail validée de dfci.harvard.edu - Page d'accueil

Epigenetics transcription steroid receptors hormone dependent cancer CRISPR screens


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Model-based analysis of ChIP-Seq (MACS) Y Zhang, T Liu, CA Meyer, J Eeckhoute, DS Johnson, BE Bernstein, ... Genome biology 9, 1-9, 2008	16918	2008
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response P Jiang, S Gu, D Pan, J Fu, A Sahu, X Hu, Z Li, N Traugh, X Bu, B Li, J Liu, ... Nature medicine 24 (10), 1550-1558, 2018	3771	2018
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens W Li, H Xu, T Xiao, L Cong, MI Love, F Zhang, RA Irizarry, JS Liu, ... Genome biology 15, 1-12, 2014	2218	2014
Cofactor dynamics and sufficiency in estrogen receptor–regulated transcription Y Shang, X Hu, J DiRenzo, MA Lazar, M Brown Cell 103 (6), 843-852, 2000	2038	2000
Genome-wide analysis of estrogen receptor binding sites JS Carroll, CA Meyer, J Song, W Li, TR Geistlinger, J Eeckhoute, ... Nature genetics 38 (11), 1289-1297, 2006	1651	2006
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1 JS Carroll, XS Liu, AS Brodsky, W Li, CA Meyer, AJ Szary, J Eeckhoute, ... Cell 122 (1), 33-43, 2005	1598	2005
Molecular determinants for the tissue specificity of SERMs Y Shang, M Brown Science 295 (5564), 2465-2468, 2002	1435	2002
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription M Lupien, J Eeckhoute, CA Meyer, Q Wang, Y Zhang, W Li, JS Carroll, ... Cell 132 (6), 958-970, 2008	1141	2008
The CAG repeat within the androgen receptor gene and its relationship to prostate cancer E Giovannucci, MJ Stampfer, K Krithivas, M Brown, A Brufsky, J Talcott, ... Proceedings of the National Academy of Sciences 94 (7), 3320-3323, 1997	1097	1997
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer Q Wang, W Li, Y Zhang, X Yuan, K Xu, J Yu, Z Chen, R Beroukhim, ... Cell 138 (2), 245-256, 2009	1089	2009
Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance SY Ku, S Rosario, Y Wang, P Mu, M Seshadri, ZW Goodrich, ... Science 355 (6320), 78-83, 2017	1003	2017
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent K Xu, ZJ Wu, AC Groner, HH He, C Cai, RT Lis, X Wu, EC Stack, M Loda, ... Science 338 (6113), 1465-1469, 2012	990	2012
X chromosomal abnormalities in basal-like human breast cancer AL Richardson, ZC Wang, A De Nicolo, X Lu, M Brown, A Miron, X Liao, ... Cancer cell 9 (2), 121-132, 2006	966	2006
Differential activation of peroxisome proliferator-activated receptors by eicosanoids (∗) K Yu, W Bayona, CB Kallen, HP Harding, CP Ravera, G McMahon, ... Journal of Biological Chemistry 270 (41), 23975-23983, 1995	926	1995
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway X Chen, D Iliopoulos, Q Zhang, Q Tang, MB Greenblatt, M Hatziapostolou, ... Nature 508 (7494), 103-107, 2014	900	2014
Formation of the androgen receptor transcription complex Y Shang, M Myers, M Brown Molecular cell 9 (3), 601-610, 2002	885	2002
Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription S Halachmi, E Marden, G Martin, H MacKay, C Abbondanza, M Brown Science 264 (5164), 1455-1458, 1994	830	1994
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth Q Wang, W Li, XS Liu, JS Carroll, OA Jänne, EK Keeton, AM Chinnaiyan, ... Molecular cell 27 (3), 380-392, 2007	780	2007
A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing D Pan, A Kobayashi, P Jiang, L Ferrari de Andrade, RE Tay, AM Luoma, ... Science 359 (6377), 770-775, 2018	778	2018
Cistrome: an integrative platform for transcriptional regulation studies T Liu, JA Ortiz, L Taing, CA Meyer, B Lee, Y Zhang, H Shin, SS Wong, ... Genome biology 12, 1-10, 2011	762	2011

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