|Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability|
D Fukumura, T Gohongi, A Kadambi, Y Izumi, J Ang, CO Yun, DG Buerk, ...
Proceedings of the National Academy of Sciences 98 (5), 2604-2609, 2001
|Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy|
JH Kim, YS Lee, H Kim, JH Huang, AR Yoon, CO Yun
Journal of the National Cancer Institute 98 (20), 1482-1493, 2006
|Tumor–host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor β1|
T Gohongi, D Fukumura, Y Boucher, CO Yun, GA Soff, C Compton, ...
Nature medicine 5 (10), 1203-1208, 1999
|VEGF-specific short hairpin RNA–expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth|
JY Yoo, JH Kim, YG Kwon, EC Kim, NK Kim, HJ Choi, CO Yun
Molecular Therapy 15 (2), 295-302, 2007
|Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model|
YS Lee, JH Kim, KJ Choi, IK Choi, H Kim, S Cho, BC Cho, CO Yun
Clinical cancer research 12 (19), 5859-5868, 2006
|Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin|
Y Son, EH Kim, JY Kim, SU Kim, TK Kwon, AR Yoon, CO Yun, KS Choi
Cancer research 67 (17), 8274-8284, 2007
|Evolution of oncolytic adenovirus for cancer treatment|
JW Choi, JS Lee, SW Kim, CO Yun
Advanced drug delivery reviews 64 (8), 720-729, 2012
|Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: role of VEGF-receptor 2 and host VEGF-A|
A Kadambi, CM Carreira, C Yun, TP Padera, DE Dolmans, P Carmeliet, ...
Cancer research 61 (6), 2404-2408, 2001
|Strategies to increase drug penetration in solid tumors|
IK Choi, R Strauss, M Richter, CO Yun, A Lieber
Frontiers in oncology 3, 193, 2013
|Ad-mTERT-Δ19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell …|
E Kim, JH Kim, HY Shin, H Lee, JM Yang, J Kim, JH Sohn, H Kim, CO Yun
Human gene therapy 14 (15), 1415-1428, 2003
|Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect|
KJ Choi, JH Kim, YS Lee, J Kim, BS Suh, H Kim, S Cho, JH Sohn, GE Kim, ...
Gene therapy 13 (13), 1010-1020, 2006
|Correlation of KIT and platelet-derived growth factor receptor α mutations with gene activation and expression profiles in gastrointestinal stromal tumors|
HJ Kang, SW Nam, H Kim, H Rhee, NG Kim, H Kim, WJ Hyung, SH Noh, ...
Oncogene 24 (6), 1066-1074, 2005
|Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL|
JH Huang, SN Zhang, KJ Choi, IK Choi, JH Kim, M Lee, H Kim, CO Yun
Molecular Therapy 18 (2), 264-274, 2010
|Vascular endothelial growth factor (VEGF) signaling regulates hippocampal neurons by elevation of intracellular calcium and activation of calcium/calmodulin protein kinase II …|
BW Kim, M Choi, YS Kim, H Park, HR Lee, CO Yun, EJ Kim, JS Choi, ...
Cellular signalling 20 (4), 714-725, 2008
|Bypassing immunization: optimized design of “designer T cells” against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA|
KF Nolan, CO Yun, Y Akamatsu, JC Murphy, SO Leung, EJ Beecham, ...
Clinical cancer research 5 (12), 3928-3941, 1999
|Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1|
WI Choi, BN Jeon, CO Yun, PH Kim, SE Kim, KY Choi, SH Kim, MW Hur
Journal of Biological Chemistry 284 (19), 12633-12644, 2009
|Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors|
CO Yun, KF Nolan, EJ Beecham, RA Reisfeld, P Junghans
Neoplasia 2 (5), 449-459, 2000
|Short hairpin RNA-expressing oncolytic adenovirus-mediated inhibition of IL-8: effects on antiangiogenesis and tumor growth inhibition|
JY Yoo, JH Kim, J Kim, JH Huang, SN Zhang, YA Kang, H Kim, CO Yun
Gene therapy 15 (9), 635-651, 2008
|Relaxin-expressing, fiber chimeric oncolytic adenovirus prolongs survival of tumor-bearing mice|
S Ganesh, MG Edick, N Idamakanti, M Abramova, M VanRoey, ...
Cancer research 67 (9), 4399-4407, 2007
|Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rβ 2 or IL-18Rα|
IK Choi, JS Lee, SN Zhang, J Park, KM Lee, CH Sonn, CO Yun
Gene therapy 18 (9), 898-909, 2011