| Recent advancements of coumarin-based anticancer agents: An up-to-date review T Al-Warhi, A Sabt, EB Elkaeed, WM Eldehna Bioorganic Chemistry 103, 104163, 2020 | 160 | 2020 |
| Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment A Angeli, F Carta, A Nocentini, JY Winum, R Zalubovskis, A Akdemir, ... Metabolites 10 (10), 412, 2020 | 124 | 2020 |
| 1-Piperazinylphthalazines as potential VEGFR-2 inhibitors and anticancer agents: synthesis and in vitro biological evaluation SM Abou-Seri, WM Eldehna, MM Ali, DA Abou El Ella European journal of medicinal chemistry 107, 165-179, 2016 | 122 | 2016 |
| Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene) thiazolidin-2-ylidene) amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and … WM Eldehna, MF Abo-Ashour, A Nocentini, P Gratteri, IH Eissa, M Fares, ... European journal of medicinal chemistry 139, 250-262, 2017 | 121 | 2017 |
| Design, synthesis and QSAR study of certain isatin-pyridine hybrids as potential anti-proliferative agents WM Eldehna, A Altoukhy, H Mahrous, HA Abdel-Aziz European Journal of Medicinal Chemistry 90, 684-694, 2015 | 112 | 2015 |
| Novel coumarin-6-sulfonamides as apoptotic anti-proliferative agents: synthesis, in vitro biological evaluation, and QSAR studies A Sabt, OM Abdelhafez, RS El-Haggar, HMF Madkour, WM Eldehna, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 1095-1107, 2018 | 100 | 2018 |
| Design, synthesis and antitubercular activity of certain nicotinic acid hydrazides WM Eldehna, M Fares, MM Abdel-Aziz, HA Abdel-Aziz Molecules 20 (5), 8800-8815, 2015 | 100 | 2015 |
| Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC … WM Eldehna, MF Abo-Ashour, A Nocentini, RS El-Haggar, S Bua, ... European journal of medicinal chemistry 162, 147-160, 2019 | 89 | 2019 |
| Improvement of antibacterial activity of some sulfa drugs through linkage to certain phthalazin-1 (2H)-one scaffolds HS Ibrahim, WM Eldehna, HA Abdel-Aziz, MM Elaasser, MM Abdel-Aziz European journal of medicinal chemistry 85, 480-486, 2014 | 89 | 2014 |
| Novel indole-thiazolidinone conjugates: Design, synthesis and whole-cell phenotypic evaluation as a novel class of antimicrobial agents MF Abo-Ashour, WM Eldehna, RF George, MM Abdel-Aziz, MM Elaasser, ... European Journal of Medicinal Chemistry 160, 49-60, 2018 | 82 | 2018 |
| Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII WM Eldehna, M Fares, M Ceruso, HA Ghabbour, SM Abou-Seri, ... European journal of medicinal chemistry 110, 259-266, 2016 | 82 | 2016 |
| Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1 … WM Eldehna, SM Abou-Seri, AM El Kerdawy, RR Ayyad, AM Hamdy, ... European Journal of Medicinal Chemistry 113, 50-62, 2016 | 79 | 2016 |
| Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA … WM Eldehna, H Almahli, GH Al-Ansary, HA Ghabbour, MH Aly, OE Ismael, ... Journal of Enzyme Inhibition and Medicinal Chemistry 32 (1), 600-613, 2017 | 78 | 2017 |
| Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents WM Eldehna, GS Hassan, ST Al-Rashood, T Al-Warhi, AE Altyar, ... Journal of enzyme inhibition and medicinal chemistry 34 (1), 322-332, 2019 | 76 | 2019 |
| Pyridine-ureas as potential anticancer agents: synthesis and in vitro biological evaluation M El-Naggar, H Almahli, HS Ibrahim, WM Eldehna, HA Abdel-Aziz Molecules 23 (6), 1459, 2018 | 71 | 2018 |
| Design and synthesis of thiazolidine-2, 4-diones hybrids with 1, 2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: In-vitro anticancer evaluation and in … MS Taghour, H Elkady, WM Eldehna, NM El-Deeb, AM Kenawy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1903-1917, 2022 | 70 | 2022 |
| Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer WM Eldehna, A Nocentini, ST Al-Rashood, GS Hassan, HM Alkahtani, ... Bioorganic Chemistry 81, 425-432, 2018 | 68 | 2018 |
| Novel [(3-indolylmethylene)hydrazono]indolin-2-ones as apoptotic anti-proliferative agents: design, synthesis and in vitro biological evaluation WM Eldehna, MF Abo-Ashour, HS Ibrahim, GH Al-Ansary, HA Ghabbour, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 686-700, 2018 | 68 | 2018 |
| 3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico … MF Abo-Ashour, WM Eldehna, A Nocentini, A Bonardi, S Bua, HS Ibrahim, ... European Journal of Medicinal Chemistry 184, 111768, 2019 | 67 | 2019 |
| Development of novel synthesized phthalazinone-based PARP-1 inhibitors with apoptosis inducing mechanism in lung cancer H Almahli, E Hadchity, MY Jaballah, R Daher, HA Ghabbour, MM Kabil, ... Bioorganic Chemistry 77, 443-456, 2018 | 66 | 2018 |
Prof. Hatem A. Abdel-AzizDepartment of Applied Organic Chemistry, National Research Centre, Cairo, EgyptAdresse e-mail validée de nrc.sci.eg
