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Nathaniel Sharp
Nathaniel Sharp
Assistant Professor, University of Wisconsin-Madison
Adresse e-mail validée de wisc.edu - Page d'accueil
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The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast
NP Sharp, L Sandell, CG James, SP Otto
Proceedings of the National Academy of Sciences 115 (22), E5046-E5055, 2018
1102018
Evidence for elevated mutation rates in low-quality genotypes
NP Sharp, AF Agrawal
Proceedings of the National Academy of Sciences 109 (16), 6142-6146, 2012
1012012
Local adaptation interacts with expansion load during range expansion: maladaptation reduces expansion load
KJ Gilbert, NP Sharp, AL Angert, GL Conte, JA Draghi, F Guillaume, ...
The American Naturalist 189 (4), 368-380, 2017
882017
MATING DENSITY AND THE STRENGTH OF SEXUAL SELECTION AGAINST DELETERIOUS ALLELES IN DROSOPHILA MELANOGASTER
NP Sharp, AF Agrawal
Evolution: International Journal of Organic Evolution 62 (4), 857-867, 2008
872008
Male‐biased fitness effects of spontaneous mutations in Drosophila melanogaster
NP Sharp, AF Agrawal
Evolution 67 (4), 1189-1195, 2013
862013
Sexual antagonism for resistance and tolerance to infection in Drosophila melanogaster
CM Vincent, NP Sharp
Proceedings of the Royal Society B: Biological Sciences 281 (1788), 20140987, 2014
722014
Low Genetic Quality Alters Key Dimensions of the Mutational Spectrum
NP Sharp, AF Agrawal
PLoS Biology 14 (3), e1002419, 2016
482016
Evolution of sex: Using experimental genomics to select among competing theories
NP Sharp, SP Otto
Bioessays 38 (8), 751-757, 2016
392016
Selection, Epistasis, and Parent‐of‐Origin Effects on Deleterious Mutations across Environments in Drosophila melanogaster
AD Wang, NP Sharp, CC Spencer, K Tedman-Aucoin, AF Agrawal
The American Naturalist 174 (6), 863-874, 2009
352009
Sexual Selection and the Random Union of Gametes: Testing for a Correlation in Fitness between Mates in Drosophila melanogaster
NP Sharp, AF Agrawal
The American Naturalist 174 (5), 613-622, 2009
242009
Relative effectiveness of mating success and sperm competition at eliminating deleterious mutations in Drosophila melanogaster
SCA Clark, NP Sharp, L Rowe, AF Agrawal
PLoS One 7 (5), e37351, 2012
232012
An experimental test of the mutation-selection balance model for the maintenance of genetic variance in fitness components
NP Sharp, AF Agrawal
Proceedings of the Royal Society B 285 (1890), 20181864, 2018
212018
Sensitivity of the distribution of mutational fitness effects to environment, genetic background, and adaptedness: a case study with Drosophila
AD Wang, NP Sharp, AF Agrawal
Evolution 68 (3), 840-853, 2014
212014
The effect of parasites on sex differences in selection
NP Sharp, CM Vincent
Heredity 114 (4), 367-372, 2015
192015
The population genetics of ploidy change in unicellular fungi
AC Gerstein, NP Sharp
FEMS microbiology reviews 45 (5), fuab006, 2021
152021
Fitness effects of mutations: an assessment of PROVEAN predictions using mutation accumulation data
L Sandell, NP Sharp
Genome Biology and Evolution 14 (1), evac004, 2022
132022
Mutations matter even if proteins stay the same
N Sharp
Nature 606 (7915), 657-659, 2022
112022
The decline in fitness with inbreeding: evidence for negative dominance‐by‐dominance epistasis in Drosophila melanogaster
NP Sharp, AF Agrawal
Journal of evolutionary biology 29 (4), 857-864, 2016
92016
Are mutations usually deleterious? A perspective on the fitness effects of mutation accumulation
K Bao, RH Melde, NP Sharp
Evolutionary ecology 36 (5), 753-766, 2022
42022
Recent insights into the evolution of mutation rates in yeast
RH Melde, K Bao, NP Sharp
Current Opinion in Genetics & Development 76, 101953, 2022
32022
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