Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide K Brendel, E Comets, C Laffont, C Laveille, F Mentré Pharmaceutical research 23, 2036-2049, 2006 | 377 | 2006 |
Similarity of bisphenol A pharmacokinetics in rhesus monkeys and mice: relevance for human exposure JA Taylor, FS Vom Saal, WV Welshons, B Drury, G Rottinghaus, PA Hunt, ... Environmental health perspectives 119 (4), 422-430, 2011 | 326 | 2011 |
Efficacy and safety of a monthly buprenorphine depot injection for opioid use disorder: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial BR Haight, SM Learned, CM Laffont, PJ Fudala, Y Zhao, AS Garofalo, ... The Lancet 393 (10173), 778-790, 2019 | 232 | 2019 |
Are population pharmacokinetic and/or pharmacodynamic models adequately evaluated? A survey of the literature from 2002 to 2004 K Brendel, C Dartois, E Comets, A Lemenuel-Diot, C Laveille, ... Clinical pharmacokinetics 46, 221-234, 2007 | 215 | 2007 |
Intestinal secretion is a major route for parent ivermectin elimination in the rat CM Laffont, PL Toutain, M Alvinerie, A Bousquet-Mélou Drug metabolism and disposition 30 (6), 626-630, 2002 | 134 | 2002 |
Licking behaviour and environmental contamination arising from pour-on ivermectin for cattle CM Laffont, M Alvinerie, A Bousquet-Mélou, PL Toutain International Journal for Parasitology 31 (14), 1687-1692, 2001 | 128 | 2001 |
Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey C Dartois, K Brendel, E Comets, CM Laffont, C Laveille, B Tranchand, ... British journal of clinical pharmacology 64 (5), 603-612, 2007 | 109 | 2007 |
Evaluation of different tests based on observations for external model evaluation of population analyses K Brendel, E Comets, C Laffont, F Mentré Journal of pharmacokinetics and pharmacodynamics 37, 49-65, 2010 | 104 | 2010 |
Gentamicin Nephrotoxicity – A Comparison of In Vitro Findings with In VivoExperiments in Equines MR Van der Harst, S Bull, CM Laffont, WR Klein Veterinary research communications 29, 247-261, 2005 | 71 | 2005 |
Optimizing ciprofloxacin dosing in intensive care unit patients through the use of population pharmacokinetic–pharmacodynamic analysis and Monte Carlo simulations D Khachman, JM Conil, B Georges, S Saivin, G Houin, PL Toutain, ... Journal of antimicrobial chemotherapy 66 (8), 1798-1809, 2011 | 67 | 2011 |
Factors for hematopoietic toxicity of carboplatin: refining the targeting of carboplatin systemic exposure A Schmitt, L Gladieff, CM Laffont, A Evrard, JC Boyer, A Lansiaux, ... J Clin Oncol 28 (30), 4568-4574, 2010 | 64 | 2010 |
A pharmacokinetic model to document the actual disposition of topical ivermectin in cattle CM Laffont, A Bousquet‐mélou, D Bralet, M Alvinerie, J Fink-Gremmels, ... Veterinary research 34 (4), 445-460, 2003 | 62 | 2003 |
Population pharmacokinetic modeling after repeated administrations of RBP‐6000, a new, subcutaneously injectable, long‐acting, sustained‐release formulation of buprenorphine … CM Laffont, R Gomeni, C Heidbreder, JP Jones Iii, AF Nasser The Journal of Clinical Pharmacology 56 (7), 806-815, 2016 | 60 | 2016 |
RB-US-13-0001 Study Investigators.(2019). Efficacy and safety of a monthly buprenorphine depot injection for opioid use disorder: A multicentre, randomised, double-blind … BR Haight, SM Learned, CM Laffont, PJ Fudala, Y Zhao, AS Garofalo, ... Lancet 393 (10173), 778-790, 0 | 50 | |
Population Pharmacokinetics and Prediction of Dopamine D2 Receptor Occupancy After Multiple Doses of RBP‐7000, a New Sustained‐Release Formulation of … CM Laffont, R Gomeni, B Zheng, C Heidbreder, PJ Fudala, AF Nasser Clinical pharmacokinetics 53, 533-543, 2014 | 47 | 2014 |
A whole-body physiologically based pharmacokinetic (WB-PBPK) model of ciprofloxacin: a step towards predicting bacterial killing at sites of infection MW Sadiq, EI Nielsen, D Khachman, JM Conil, B Georges, G Houin, ... Journal of pharmacokinetics and pharmacodynamics 44, 69-79, 2017 | 46 | 2017 |
Pharmacogenetics and population pharmacokinetics: impact of the design on three tests using the SAEM algorithm J Bertrand, E Comets, CM Laffont, M Chenel, F Mentré Journal of pharmacokinetics and pharmacodynamics 36, 317-339, 2009 | 44 | 2009 |
Population pharmacokinetic modeling and simulation to guide dose selection for RBP‐7000, a new sustained‐release formulation of risperidone CM Laffont, R Gomeni, B Zheng, C Heidbreder, PJ Fudala, AF Nasser The Journal of Clinical Pharmacology 55 (1), 93-103, 2015 | 36 | 2015 |
Use of Monte Carlo simulation to determine pharmacodynamic cutoffs of amoxicillin to establish a breakpoint for antimicrobial susceptibility testing in pigs JF Rey, CM Laffont, S Croubels, P De Backer, C Zemirline, E Bousquet, ... American Journal of Veterinary Research 75 (2), 124-131, 2014 | 35 | 2014 |
Development of a complex parent-metabolite joint population pharmacokinetic model J Bertrand, CM Laffont, F Mentré, M Chenel, E Comets The AAPS journal 13, 390-404, 2011 | 35 | 2011 |