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| Identification and pharmacological characterization of cholesterol-5, 6-epoxide hydrolase as a target for tamoxifen and AEBS ligands P de Medina, MR Paillasse, G Segala, M Poirot, S Silvente-Poirot Proceedings of the National Academy of Sciences 107 (30), 13520-13525, 2010 | 131 | 2010 |
| Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties P De Médina, MR Paillasse, G Segala, M Voisin, L Mhamdi, F Dalenc, ... Nature communications 4 (1), 1840, 2013 | 115 | 2013 |
| Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation P de Medina, S Silvente-Poirot, M Poirot Autophagy 5 (7), 1066-1067, 2009 | 110 | 2009 |
| Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor M Voisin, P De Medina, A Mallinger, F Dalenc, E Huc-Claustre, ... Proceedings of the National Academy of Sciences 114 (44), E9346-E9355, 2017 | 109 | 2017 |
| Dendrogenin A drives LXR to trigger lethal autophagy in cancers G Segala, M David, P De Médina, MC Poirot, N Serhan, F Vergez, ... Nature communications 8 (1), 1903, 2017 | 97 | 2017 |
| Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells P De Médina, BL Payre, J Bernad, I Bosser, B Pipy, S Silvente-Poirot, ... Journal of Pharmacology and Experimental Therapeutics 308 (3), 1165-1173, 2004 | 96 | 2004 |
| Molecular characterization of the microsomal tamoxifen binding site B Kedjouar, P de Médina, M Oulad-Abdelghani, B Payré, ... Journal of Biological Chemistry 279 (32), 34048-34061, 2004 | 95 | 2004 |
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| Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism P De Médina, B Payré, N Boubekeur, J Bertrand-Michel, F Tercé, ... Cell Death & Differentiation 16 (10), 1372-1384, 2009 | 88 | 2009 |
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| Cholesterol epoxide hydrolase and cancer S Silvente-Poirot, M Poirot Current opinion in pharmacology 12 (6), 696-703, 2012 | 87 | 2012 |
| Arginine 336 and asparagine 333 of the human cholecystokinin-A receptor binding site interact with the penultimate aspartic acid and the C-terminal amide of cholecystokinin V Gigoux, C Escrieut, JA Fehrentz, S Poirot, B Maigret, L Moroder, D Gully, ... Journal of Biological Chemistry 274 (29), 20457-20464, 1999 | 86 | 1999 |
| Met-195 of the cholecystokinin-A receptor interacts with the sulfated tyrosine of cholecystokinin and is crucial for receptor transition to high affinity state V Gigoux, C Escrieut, S Silvente-Poirot, B Maigret, L Gouilleux, ... Journal of biological chemistry 273 (23), 14380-14386, 1998 | 84 | 1998 |
