| A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products RW Huigens III, KC Morrison, RW Hicklin, TA Flood Jr, MF Richter, ... Nature chemistry 5 (3), 195-202, 2013 | 323 | 2013 |
| Synergistic effects between conventional antibiotics and 2-aminoimidazole-derived antibiofilm agents SA Rogers, RW Huigens III, J Cavanagh, C Melander Antimicrobial agents and chemotherapy 54 (5), 2112-2118, 2010 | 261 | 2010 |
| Inhibition of Pseudomonas aeruginosa Biofilm Formation with Bromoageliferin Analogues RW Huigens, JJ Richards, G Parise, TE Ballard, W Zeng, R Deora, ... Journal of the American Chemical Society 129 (22), 6966-6967, 2007 | 187 | 2007 |
| Synthesis and Screening of an Oroidin Library against Pseudomonas aeruginosa Biofilms JJ Richards, TE Ballard, RW Huigens III, C Melander ChemBioChem 9 (8), 1267-1279, 2008 | 176 | 2008 |
| A 2-aminobenzimidazole that inhibits and disperses gram-positive biofilms through a zinc-dependent mechanism SA Rogers, RW Huigens Iii, C Melander Journal of the American Chemical Society 131 (29), 9868-9869, 2009 | 122 | 2009 |
| Phenazine antibiotic inspired discovery of potent bromophenazine antibacterial agents against Staphylococcus aureus and Staphylococcus epidermidis NV Borrero, F Bai, C Perez, BQ Duong, JR Rocca, S Jin, RW Huigens III Organic & biomolecular chemistry 12 (6), 881-886, 2014 | 99 | 2014 |
| The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii RW Huigens III, S Reyes, CS Reed, C Bunders, SA Rogers, ... Bioorganic & medicinal chemistry 18 (2), 663-674, 2010 | 97 | 2010 |
| Control of bacterial biofilms with marine alkaloid derivatives RW Huigens Iii, L Ma, C Gambino, PDR Moeller, A Basso, J Cavanagh, ... Molecular BioSystems 4 (6), 614-621, 2008 | 96 | 2008 |
| Halogenated Phenazines that Potently Eradicate Biofilms, MRSA Persister Cells in Non‐Biofilm Cultures, and Mycobacterium tuberculosis AT Garrison, Y Abouelhassan, D Kallifidas, F Bai, M Ukhanova, V Mai, ... Angewandte Chemie 127 (49), 15032-15036, 2015 | 92 | 2015 |
| Evaluation of dihydrooroidin as an antifouling additive in marine paint C Melander, PDR Moeller, TE Ballard, JJ Richards, RW Huigens III, ... International biodeterioration & biodegradation 63 (4), 529-532, 2009 | 88 | 2009 |
| Discovery of quinoline small molecules with potent dispersal activity against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a … Y Abouelhassan, AT Garrison, GM Burch, W Wong, VM Norwood IV, ... Bioorganic & Medicinal Chemistry Letters 24 (21), 5076-5080, 2014 | 86 | 2014 |
| Inhibition of Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa biofilm formation with a class of TAGE-triazole conjugates RW Huigens Iii, SA Rogers, AT Steinhauer, C Melander Organic & biomolecular chemistry 7 (4), 794-802, 2009 | 85 | 2009 |
| Harnessing the chemistry of the indole heterocycle to drive discoveries in biology and medicine VM Norwood IV, RW Huigens III ChemBioChem 20 (18), 2273-2297, 2019 | 78 | 2019 |
| Structure–activity relationships of a diverse class of halogenated phenazines that targets persistent, antibiotic-tolerant bacterial biofilms and Mycobacterium tuberculosis AT Garrison, Y Abouelhassan, VM Norwood IV, D Kallifidas, F Bai, ... Journal of Medicinal Chemistry 59 (8), 3808-3825, 2016 | 77 | 2016 |
| Inhibition and dispersion of proteobacterial biofilms W Robert III, T EricáBallard Chemical communications, 1698-1700, 2008 | 75 | 2008 |
| Recent progress in natural-product-inspired programs aimed to address antibiotic resistance and tolerance Y Abouelhassan, AT Garrison, H Yang, A Chávez-Riveros, GM Burch, ... Journal of medicinal chemistry 62 (17), 7618-7642, 2019 | 74 | 2019 |
| A tryptoline ring‐distortion strategy leads to complex and diverse biologically active molecules from the indole alkaloid yohimbine NG Paciaroni, R Ratnayake, JH Matthews, VM Norwood IV, AC Arnold, ... Chemistry–A European Journal 23 (18), 4327-4335, 2017 | 70 | 2017 |
| Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria Y Abouelhassan, Q Yang, H Yousaf, MT Nguyen, M Rolfe, GS Schultz, ... International journal of antimicrobial agents 49 (2), 247-251, 2017 | 66 | 2017 |
| Dual targeting of the Warburg effect with a glucose-conjugated lactate dehydrogenase inhibitor EC Calvaresi, C Granchi, T Tuccinardi, V Di Bussolo, RW Huigens III, ... Chembiochem: a European journal of chemical biology 14 (17), 2263, 2013 | 59 | 2013 |
| Synthesis and biological activity of 2-aminoimidazole triazoles accessed by Suzuki–Miyaura cross-coupling S Reyes, RW Huigens III, Z Su, ML Simon, C Melander Organic & biomolecular chemistry 9 (8), 3041-3049, 2011 | 54 | 2011 |
