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Adrian Keatinge-Clay
Adrian Keatinge-Clay
Professor of Molecular Biosciences & Chemistry, UT Austin
Verified email at utexas.edu - Homepage
Title
Cited by
Cited by
Year
The structures of type I polyketide synthases
AT Keatinge-Clay
Natural product reports 29 (10), 1050-1073, 2012
3832012
A tylosin ketoreductase reveals how chirality is determined in polyketides
AT Keatinge-Clay
Chemistry & biology 14 (8), 898-908, 2007
3612007
The structure of a ketoreductase determines the organization of the β-carbon processing enzymes of modular polyketide synthases
AT Keatinge-Clay, RM Stroud
Structure 14 (4), 737-748, 2006
2712006
Crystal structure of the erythromycin polyketide synthase dehydratase
A Keatinge-Clay
Journal of molecular biology 384 (4), 941-953, 2008
2412008
High-resolution macromolecular NMR spectroscopy inside living cells
Z Serber, AT Keatinge-Clay, R Ledwidge, AE Kelly, SM Miller, V Dötsch
Journal of the American Chemical Society 123 (10), 2446-2447, 2001
2382001
An antibiotic factory caught in action
AT Keatinge-Clay, DA Maltby, KF Medzihradszky, C Khosla, RM Stroud
Nature structural & molecular biology 11 (9), 888-893, 2004
2172004
Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA: ACP transacylase
AT Keatinge-Clay, AA Shelat, DF Savage, SC Tsai, LJW Miercke, ...
Structure 11 (2), 147-154, 2003
1772003
Enzymatic extender unit generation for in vitro polyketide synthase reactions: structural and func-tional showcasing of Streptomyces coelicolor MatB
AJ Hughes, A Keatinge-Clay
Chemistry & biology 18 (2), 165-176, 2011
1502011
Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase
J Zheng, CA Taylor, SK Piasecki, AT Keatinge-Clay
Structure 18 (8), 913-922, 2010
1242010
The structure of SpnF, a standalone enzyme that catalyzes [4+ 2] cycloaddition
CD Fage, EA Isiorho, Y Liu, DT Wagner, H Liu, AT Keatinge-Clay
Nature chemical biology 11 (4), 256-258, 2015
1142015
Divergence of multimodular polyketide synthases revealed by a didomain structure
J Zheng, DC Gay, B Demeler, MA White, AT Keatinge-Clay
Nature chemical biology 8 (7), 615-621, 2012
1062012
Stereocontrol within polyketide assembly lines
AT Keatinge-Clay
Natural product reports 33 (2), 141-149, 2016
1042016
Generalized bacterial genome editing using mobile group II introns and Cre‐lox
PJ Enyeart, SM Chirieleison, MN Dao, J Perutka, EM Quandt, J Yao, ...
Molecular systems biology 9 (1), 685, 2013
1022013
Crystal structure of the priming β-ketosynthase from the R1128 polyketide biosynthetic pathway
H Pan, S Tsai, ES Meadows, LJW Miercke, AT Keatinge-Clay, J O'Connell, ...
Structure 10 (11), 1559-1568, 2002
1022002
Employing modular polyketide synthase ketoreductases as biocatalysts in the preparative chemoenzymatic syntheses of diketide chiral building blocks
SK Piasecki, CA Taylor, JF Detelich, J Liu, J Zheng, A Komsoukaniants, ...
Chemistry & biology 18 (10), 1331-1340, 2011
972011
Stereospecificity of the dehydratase domain of the erythromycin polyketide synthase
CR Valenzano, YO You, A Garg, A Keatinge-Clay, C Khosla, DE Cane
Journal of the American Chemical Society 132 (42), 14697-14699, 2010
952010
A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase
DC Gay, G Gay, AJ Axelrod, M Jenner, C Kohlhaas, A Kampa, NJ Oldham, ...
Structure 22 (3), 444-451, 2014
832014
The uncommon enzymology of cis-acyltransferase assembly lines
AT Keatinge-Clay
Chemical reviews 117 (8), 5334-5366, 2017
802017
Polyketide synthase modules redefined
AT Keatinge-Clay
Angewandte Chemie (International ed. in English) 56 (17), 4658, 2017
772017
Structure and stereospecificity of the dehydratase domain from the terminal module of the rifamycin polyketide synthase
D Gay, YO You, A Keatinge-Clay, DE Cane
Biochemistry 52 (49), 8916-8928, 2013
722013
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