| Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer D Herranz, M Muñoz-Martin, M Cañamero, F Mulero, B Martinez-Pastor, ... Nature communications 1 (1), 3, 2010 | 717 | 2010 |
| A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma M Puyol, A Martín, P Dubus, F Mulero, P Pizcueta, G Khan, C Guerra, ... Cancer cell 18 (1), 63-73, 2010 | 496 | 2010 |
| A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging M Murga, S Bunting, MF Montana, R Soria, F Mulero, M Canamero, Y Lee, ... Nature genetics 41 (8), 891-898, 2009 | 414 | 2009 |
| Pten positively regulates brown adipose function, energy expenditure, and longevity A Ortega-Molina, A Efeyan, E Lopez-Guadamillas, M Muñoz-Martin, ... Cell metabolism 15 (3), 382-394, 2012 | 376 | 2012 |
| A versatile drug delivery system targeting senescent cells D Muñoz‐Espín, M Rovira, I Galiana, C Giménez, B Lozano‐Torres, ... EMBO molecular medicine 10 (9), e9355, 2018 | 244 | 2018 |
| FGF21 gene therapy as treatment for obesity and insulin resistance V Jimenez, C Jambrina, E Casana, V Sacristan, S Muñoz, S Darriba, ... EMBO molecular medicine 10 (8), e8791, 2018 | 229 | 2018 |
| Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells D Tormo, A Chęcińska, D Alonso-Curbelo, E Pérez-Guijarro, E Cañón, ... Cancer cell 16 (2), 103-114, 2009 | 228 | 2009 |
| Mice with pulmonary fibrosis driven by telomere dysfunction JM Povedano, P Martinez, JM Flores, F Mulero, MA Blasco Cell reports 12 (2), 286-299, 2015 | 197 | 2015 |
| Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction C Bär, BB De Jesus, R Serrano, A Tejera, E Ayuso, V Jimenez, ... Nature communications 5 (1), 5863, 2014 | 154 | 2014 |
| Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine D Olmeda, D Cerezo-Wallis, E Riveiro-Falkenbach, PC Pennacchi, ... Nature 546 (7660), 676-680, 2017 | 146 | 2017 |
| Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK A Maraver, PJ Fernandez-Marcos, D Herranz, M Cañamero, ... Cancer cell 22 (2), 222-234, 2012 | 123 | 2012 |
| Combination of injectable multiple growth factor–releasing scaffolds and cell therapy as an advanced modality to enhance tissue neovascularization J Saif, TM Schwarz, DYS Chau, J Henstock, P Sami, SF Leicht, ... Arteriosclerosis, thrombosis, and vascular biology 30 (10), 1897-1904, 2010 | 116 | 2010 |
| Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells R Rubio, A Abarrategi, J Garcia‐Castro, L Martinez‐Cruzado, C Suarez, ... Stem cells 32 (5), 1136-1148, 2014 | 108 | 2014 |
| MiR-93 controls adiposity via inhibition of Sirt7 and Tbx3 M Cioffi, M Vallespinos-Serrano, SM Trabulo, PJ Fernandez-Marcos, ... Cell reports 12 (10), 1594-1605, 2015 | 105 | 2015 |
| Biological Properties of Solid Free Form Designed Ceramic Scaffolds with BMP-2: In Vitro and In Vivo Evaluation A Abarrategi, C Moreno-Vicente, FJ Martínez-Vázquez, A Civantos, ... PloS one 7 (3), e34117, 2012 | 105 | 2012 |
| Targeting tumor mitochondrial metabolism overcomes resistance to antiangiogenics P Navarro, MJ Bueno, I Zagorac, T Mondejar, J Sanchez, S Mouron, ... Cell reports 15 (12), 2705-2718, 2016 | 101 | 2016 |
| Complete regression of advanced pancreatic ductal adenocarcinomas upon combined inhibition of EGFR and C-RAF MT Blasco, C Navas, G Martín-Serrano, O Graña-Castro, CG Lechuga, ... Cancer cell 35 (4), 573-587. e6, 2019 | 99 | 2019 |
| ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase CJ McNees, AM Tejera, P Martínez, M Murga, F Mulero, ... Journal of cell biology 188 (5), 639-652, 2010 | 82 | 2010 |
| K-RasV14I recapitulates Noonan syndrome in mice I Hernández-Porras, S Fabbiano, AJ Schuhmacher, A Aicher, ... Proceedings of the National Academy of Sciences 111 (46), 16395-16400, 2014 | 78 | 2014 |
| Constitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome J Urosevic, V Sauzeau, ML Soto-Montenegro, S Reig, M Desco, ... Proceedings of the National Academy of Sciences 108 (12), 5015-5020, 2011 | 75 | 2011 |
