| The multifaceted role of autophagy in cancer and the microenvironment H Folkerts, S Hilgendorf, E Vellenga, E Bremer, VR Wiersma Medicinal research reviews 39 (2), 517-560, 2019 | 171 | 2019 |
| Therapeutic potential of Galectin‐9 in human disease VR Wiersma, M de Bruyn, W Helfrich, E Bremer Medicinal research reviews 33 (S1), E102-E126, 2013 | 166 | 2013 |
| Mechanisms of translocation of ER chaperones to the cell surface and immunomodulatory roles in cancer and autoimmunity VR Wiersma, M Michalak, TM Abdullah, E Bremer, P Eggleton Frontiers in oncology 5, 7, 2015 | 162 | 2015 |
| CD20-selective inhibition of CD47-SIRPα “don't eat me” signaling with a bispecific antibody-derivative enhances the anticancer activity of daratumumab, alemtuzumab and obinutuzumab PE van Bommel, Y He, I Schepel, MAJM Hendriks, VR Wiersma, ... Oncoimmunology 7 (2), e1386361, 2018 | 72 | 2018 |
| Antibody-based cancer therapy: successful agents and novel approaches D Hendriks, G Choi, M de Bruyn, VR Wiersma, E Bremer International review of cell and molecular biology 331, 289-383, 2017 | 62 | 2017 |
| The ever-expanding immunomodulatory role of calreticulin in cancer immunity M de Bruyn, VR Wiersma, W Helfrich, P Eggleton, E Bremer Frontiers in oncology 5, 35, 2015 | 59 | 2015 |
| Cell surface delivery of TRAIL strongly augments the tumoricidal activity of T cells M de Bruyn, Y Wei, VR Wiersma, DF Samplonius, HG Klip, ... Clinical Cancer Research 17 (17), 5626-5637, 2011 | 56 | 2011 |
| Galectin-9 activates and expands human T-helper 1 cells MJM Gooden, VR Wiersma, DF Samplonius, J Gerssen, RJ van Ginkel, ... PLoS One 8 (5), e65616, 2013 | 53 | 2013 |
| Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction D Hendriks, Y He, I Koopmans, VR Wiersma, RJ van Ginkel, ... Oncoimmunology 5 (8), e1202390, 2016 | 49 | 2016 |
| Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity MJM Gooden, VR Wiersma, A Boerma, N Leffers, HM Boezen, ... British Journal of Cancer 110 (6), 1535, 2014 | 45 | 2014 |
| The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux VR Wiersma, M de Bruyn, Y Wei, RJ van Ginkel, M Hirashima, T Niki, ... Autophagy 11 (8), 1373-1388, 2015 | 44 | 2015 |
| The glycan-binding protein galectin-9 has direct apoptotic activity toward melanoma cells VR Wiersma, M De Bruyn, RJ Van Ginkel, E Sigar, M Hirashima, T Niki, ... The Journal of investigative dermatology 132 (9), 2302, 2012 | 41 | 2012 |
| Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis Y He, R Bouwstra, VR Wiersma, M de Jong, HJ Lourens, R Fehrmann, ... Nature communications 10 (1), 533, 2019 | 38 | 2019 |
| Cigarette smoking acutely decreases serum levels of the chronic obstructive pulmonary disease biomarker sRAGE SD Pouwels, F Klont, M Kwiatkowski, VR Wiersma, A Faiz, ... American journal of respiratory and critical care medicine 198 (11), 1456-1458, 2018 | 36 | 2018 |
| CD20+ T cells have a predominantly Tc1 effector memory phenotype and are expanded in the ascites of patients with ovarian cancer M de Bruyn, VR Wiersma, MCA Wouters, DF Samplonius, HG Klip, ... OncoImmunology 4 (4), e999536, 2015 | 34 | 2015 |
| The neutrophil: The underdog that packs a punch in the fight against cancer N Ustyanovska Avtenyuk, N Visser, E Bremer, VR Wiersma International Journal of Molecular Sciences 21 (21), 7820, 2020 | 33 | 2020 |
| Galectin-9 Is a Possible Promoter of Immunopathology in Rheumatoid Arthritis by Activation of Peptidyl Arginine Deiminase 4 (PAD-4) in Granulocytes VR Wiersma, A Clarke, SD Pouwels, E Perry, TM Abdullah, C Kelly, ... International journal of molecular sciences 20 (16), 4046, 2019 | 32 | 2019 |
| C-type lectin-like molecule-1 (CLL1)-targeted TRAIL augments the tumoricidal activity of granulocytes and potentiates therapeutic antibody-dependent cell-mediated cytotoxicity VR Wiersma, M de Bruyn, C Shi, MJM Gooden, MCA Wouters, ... MAbs 7 (2), 321-330, 2015 | 30 | 2015 |
| The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide UM Pandya, C Egbuta, A Norman, M Trefa, CYE Chiang, VR Wiersma, ... International journal of molecular sciences 20 (2), 408, 2019 | 24 | 2019 |
| A CD 47‐blocking TRAIL fusion protein with dual pro‐phagocytic and pro‐apoptotic anticancer activity VR Wiersma, Y He, DF Samplonius, RJ van Ginkel, J Gerssen, P Eggleton, ... British journal of haematology 164 (2), 304-307, 2014 | 23 | 2014 |
