Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice B Davies, E Hatton, N Altemose, JG Hussin, F Pratto, G Zhang, AG Hinch, ... Nature 530 (7589), 171-176, 2016 | 218 | 2016 |
Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo LLP Hanssen, MT Kassouf, AM Oudelaar, D Biggs, C Preece, DJ Downes, ... Nature cell biology 19 (8), 952-961, 2017 | 211 | 2017 |
Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function S Lakhal-Littleton, M Wolna, CA Carr, JJJ Miller, HC Christian, V Ball, ... Proceedings of the National Academy of Sciences 112 (10), 3164-3169, 2015 | 206 | 2015 |
Targeted deletion of the epididymal receptor HE6 results in fluid dysregulation and male infertility B Davies, C Baumann, C Kirchhoff, R Ivell, R Nubbemeyer, UF Habenicht, ... Molecular and cellular biology 24 (19), 8642-8648, 2004 | 179 | 2004 |
An essential cell-autonomous role for hepcidin in cardiac iron homeostasis S Lakhal-Littleton, M Wolna, YJ Chung, HC Christian, LC Heather, ... Elife 5, e19804, 2016 | 178 | 2016 |
CRISPR-Cas orthologues and variants: optimizing the repertoire, specificity and delivery of genome engineering tools A Cebrian-Serrano, B Davies Mammalian Genome 28, 247-261, 2017 | 168 | 2017 |
Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome Z Xu, L Thomas, B Davies, R Chalmers, M Smith, W Brown BMC biotechnology 13, 1-17, 2013 | 163 | 2013 |
Reduced anxiety-related behaviour in transgenic mice overexpressing serotonin1A receptors H Kusserow, B Davies, H Hörtnagl, I Voigt, T Stroh, B Bert, DR Deng, ... Molecular brain research 129 (1-2), 104-116, 2004 | 159 | 2004 |
Oxr1 is essential for protection against oxidative stress-induced neurodegeneration PL Oliver, MJ Finelli, B Edwards, E Bitoun, DL Butts, EBE Becker, ... PLoS genetics 7 (10), e1002338, 2011 | 156 | 2011 |
Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development N Sacilotto, R Monteiro, M Fritzsche, PW Becker, L Sanchez-del-Campo, ... Proceedings of the National Academy of Sciences 110 (29), 11893-11898, 2013 | 146 | 2013 |
A comparison of exogenous promoter activity at the ROSA26 locus using a PhiC31 integrase mediated cassette exchange approach in mouse ES cells C Chen, J Krohn, S Bhattacharya, B Davies PloS one 6 (8), e23376, 2011 | 145 | 2011 |
A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection J Zeron-Medina, X Wang, E Repapi, MR Campbell, D Su, F Castro-Giner, ... Cell 155 (2), 410-422, 2013 | 132 | 2013 |
Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes B Davies, G Davies, C Preece, R Puliyadi, D Szumska, S Bhattacharya PloS one 8 (3), e60216, 2013 | 126 | 2013 |
Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in ‘FUSDelta14’knockin mice A Devoy, B Kalmar, M Stewart, H Park, B Burke, SJ Noy, Y Redhead, ... Brain 140 (11), 2797-2805, 2017 | 117 | 2017 |
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion OP Dwivedi, M Lehtovirta, B Hastoy, V Chandra, NAJ Krentz, S Kleiner, ... Nature genetics 51 (11), 1596-1606, 2019 | 112 | 2019 |
An essential role for the Zn2+ transporter ZIP7 in B cell development C Anzilotti, DJ Swan, B Boisson, M Deobagkar-Lele, C Oliveira, ... Nature immunology 20 (3), 350-361, 2019 | 111 | 2019 |
Serine proteases in rodent hippocampus BJ Davies, BS Pickard, M Steel, RGM Morris, R Lathe Journal of Biological Chemistry 273 (36), 23004-23011, 1998 | 106 | 1998 |
A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia J Adam, M Yang, C Bauerschmidt, M Kitagawa, L O’Flaherty, ... Cell reports 3 (5), 1440-1448, 2013 | 96 | 2013 |
The configuration of RPA, RAD51, and DMC1 binding in meiosis reveals the nature of critical recombination intermediates AG Hinch, PW Becker, T Li, D Moralli, G Zhang, C Bycroft, C Green, ... Molecular cell 79 (4), 689-701. e10, 2020 | 93 | 2020 |
Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm AG Hinch, G Zhang, PW Becker, D Moralli, R Hinch, B Davies, R Bowden, ... Science 363 (6433), eaau8861, 2019 | 91 | 2019 |