|Production of recombinant protein therapeutics in cultivated mammalian cells|
Nature biotechnology 22 (11), 1393, 2004
|Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation|
M Jordan, A Schallhorn, FM Wurm
Nucleic acids research 24 (4), 596-601, 1996
|Designing CD4 immunoadhesins for AIDS therapy|
DJ Capon, SM Chamow, J Mordenti, SA Marsters, T Gregory, H Mitsuya, ...
Nature 337 (6207), 525, 1989
|Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160|
PW Berman, TJ Gregory, L Riddle, GR Nakamura, MA Champe, JP Porter, ...
Nature 345 (6276), 622, 1990
|Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives|
L Baldi, DL Hacker, M Adam, FM Wurm
Biotechnology letters 29 (5), 677-684, 2007
|Transfection of adherent and suspended cells by calcium phosphate|
M Jordan, F Wurm
Methods 33 (2), 136-143, 2004
|Large-scale transient expression in mammalian cells for recombinant protein production|
F Wurm, A Bernard
Current Opinion in Biotechnology 10 (2), 156-159, 1999
|Biological properties of a CD4 immunoadhesin|
RA Byrn, J Mordenti, C Lucas, D Smith, SA Marsters, JS Johnson, ...
Nature 344 (6267), 667, 1990
|High resolution analysis of functional determinants on human tissue-type plasminogen activator.|
WF Bennett, NF Paoni, BA Keyt, D Botstein, AJ Jones, L Presta, FM Wurm, ...
Journal of Biological Chemistry 266 (8), 5191-5201, 1991
|Transient gene expression: recombinant protein production with suspension‐adapted HEK293‐EBNA cells|
P Meissner, H Pick, A Kulangara, P Chatellard, K Friedrich, FM Wurm
Biotechnology and bioengineering 75 (2), 197-203, 2001
|Serum‐free large‐scale transient transfection of CHO cells|
M Derouazi, P Girard, F Van Tilborgh, K Iglesias, N Muller, M Bertschinger, ...
Biotechnology and bioengineering 87 (4), 537-545, 2004
|CD8β endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56lck complexes|
A Arcaro, C Grégoire, TR Bakker, L Baldi, M Jordan, L Goffin, ...
Journal of Experimental Medicine 194 (10), 1485-1495, 2001
|Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions|
G Backliwal, M Hildinger, S Chenuet, S Wulhfard, M De Jesus, FM Wurm
Nucleic acids research 36 (15), e96-e96, 2008
|GFP‐expressing mammalian cells for fast, sensitive, noninvasive cell growth assessment in a kinetic mode|
L Hunt, M Jordan, M De Jesus, FM Wurm
Biotechnology and bioengineering 65 (2), 201-205, 1999
|Inducible overproduction of the mouse c-myc protein in mammalian cells|
FM Wurm, KA Gwinn, RE Kingston
Proceedings of the National Academy of Sciences 83 (15), 5414-5418, 1986
|Acrylic acid grafting and collagen immobilization on poly (ethylene terephthalate) surfaces for adherence and growth of human bladder smooth muscle cells|
I Bisson, M Kosinski, S Ruault, B Gupta, J Hilborn, F Wurm, P Frey
Biomaterials 23 (15), 3149-3158, 2002
|Development of stable cell lines for production or regulated expression using matrix attachment regions|
M Zahn-Zabal, M Kobr, PA Girod, M Imhof, P Chatellard, M de Jesus, ...
Journal of biotechnology 87 (1), 29-42, 2001
|Orbital shaker technology for the cultivation of mammalian cells in suspension|
N Muller, P Girard, DL Hacker, M Jordan, FM Wurm
Biotechnology and bioengineering 89 (4), 400-406, 2005
|25 years of recombinant proteins from reactor-grown cells—where do we go from here?|
DL Hacker, M De Jesus, FM Wurm
Biotechnology advances 27 (6), 1023-1027, 2009
|Transient gene expression in suspension HEK‐293 cells: application to large‐scale protein production|
L Baldi, N Muller, S Picasso, R Jacquet, P Girard, HP Thanh, E Derow, ...
Biotechnology progress 21 (1), 148-153, 2005