| Production of recombinant protein therapeutics in cultivated mammalian cells FM Wurm Nature biotechnology 22 (11), 1393, 2004 | 2116 | 2004 |
| Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation M Jordan, A Schallhorn, FM Wurm Nucleic acids research 24 (4), 596-601, 1996 | 900 | 1996 |
| Designing CD4 immunoadhesins for AIDS therapy DJ Capon, SM Chamow, J Mordenti, SA Marsters, T Gregory, H Mitsuya, ... Nature 337 (6207), 525, 1989 | 799 | 1989 |
| Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160 PW Berman, TJ Gregory, L Riddle, GR Nakamura, MA Champe, JP Porter, ... Nature 345 (6276), 622, 1990 | 751 | 1990 |
| Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives L Baldi, DL Hacker, M Adam, FM Wurm Biotechnology letters 29 (5), 677-684, 2007 | 289 | 2007 |
| Transfection of adherent and suspended cells by calcium phosphate M Jordan, F Wurm Methods 33 (2), 136-143, 2004 | 273 | 2004 |
| Large-scale transient expression in mammalian cells for recombinant protein production F Wurm, A Bernard Current Opinion in Biotechnology 10 (2), 156-159, 1999 | 266 | 1999 |
| Biological properties of a CD4 immunoadhesin RA Byrn, J Mordenti, C Lucas, D Smith, SA Marsters, JS Johnson, ... Nature 344 (6267), 667, 1990 | 255 | 1990 |
| High resolution analysis of functional determinants on human tissue-type plasminogen activator. WF Bennett, NF Paoni, BA Keyt, D Botstein, AJ Jones, L Presta, FM Wurm, ... Journal of Biological Chemistry 266 (8), 5191-5201, 1991 | 243 | 1991 |
| Transient gene expression: recombinant protein production with suspension‐adapted HEK293‐EBNA cells P Meissner, H Pick, A Kulangara, P Chatellard, K Friedrich, FM Wurm Biotechnology and bioengineering 75 (2), 197-203, 2001 | 231 | 2001 |
| Serum‐free large‐scale transient transfection of CHO cells M Derouazi, P Girard, F Van Tilborgh, K Iglesias, N Muller, M Bertschinger, ... Biotechnology and bioengineering 87 (4), 537-545, 2004 | 222 | 2004 |
| CD8β endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56lck complexes A Arcaro, C Grégoire, TR Bakker, L Baldi, M Jordan, L Goffin, ... Journal of Experimental Medicine 194 (10), 1485-1495, 2001 | 220 | 2001 |
| Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions G Backliwal, M Hildinger, S Chenuet, S Wulhfard, M De Jesus, FM Wurm Nucleic acids research 36 (15), e96-e96, 2008 | 214 | 2008 |
| GFP‐expressing mammalian cells for fast, sensitive, noninvasive cell growth assessment in a kinetic mode L Hunt, M Jordan, M De Jesus, FM Wurm Biotechnology and bioengineering 65 (2), 201-205, 1999 | 213 | 1999 |
| Inducible overproduction of the mouse c-myc protein in mammalian cells FM Wurm, KA Gwinn, RE Kingston Proceedings of the National Academy of Sciences 83 (15), 5414-5418, 1986 | 211 | 1986 |
| Acrylic acid grafting and collagen immobilization on poly (ethylene terephthalate) surfaces for adherence and growth of human bladder smooth muscle cells I Bisson, M Kosinski, S Ruault, B Gupta, J Hilborn, F Wurm, P Frey Biomaterials 23 (15), 3149-3158, 2002 | 191 | 2002 |
| Development of stable cell lines for production or regulated expression using matrix attachment regions M Zahn-Zabal, M Kobr, PA Girod, M Imhof, P Chatellard, M de Jesus, ... Journal of biotechnology 87 (1), 29-42, 2001 | 175 | 2001 |
| Orbital shaker technology for the cultivation of mammalian cells in suspension N Muller, P Girard, DL Hacker, M Jordan, FM Wurm Biotechnology and bioengineering 89 (4), 400-406, 2005 | 173 | 2005 |
| 25 years of recombinant proteins from reactor-grown cells—where do we go from here? DL Hacker, M De Jesus, FM Wurm Biotechnology advances 27 (6), 1023-1027, 2009 | 172 | 2009 |
| Transient gene expression in suspension HEK‐293 cells: application to large‐scale protein production L Baldi, N Muller, S Picasso, R Jacquet, P Girard, HP Thanh, E Derow, ... Biotechnology progress 21 (1), 148-153, 2005 | 150 | 2005 |
