Suivre
Chul-Jin Lee
Chul-Jin Lee
Evotec
Adresse e-mail validée de evotec.com
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Année
Fatty acyl recognition and transfer by an integral membrane S-acyltransferase
MS Rana, P Kumar, CJ Lee, R Verardi, KR Rajashankar, A Banerjee
Science 359 (6372), eaao6326, 2018
1942018
cis-Proline-mediated Ser (P) 5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72
JW Werner-Allen, CJ Lee, P Liu, NI Nicely, S Wang, AL Greenleaf, P Zhou
Journal of Biological Chemistry 286 (7), 5717-5726, 2011
1602011
Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ
J Wojtaszek, CJ Lee, S D'Souza, B Minesinger, H Kim, AD D'Andrea, ...
Journal of Biological Chemistry 287 (40), 33836-33846, 2012
1272012
Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design
CJ Lee, X Liang, X Chen, D Zeng, SH Joo, HS Chung, AW Barb, ...
Chemistry & biology 18 (1), 38-47, 2011
1072011
Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold
X Liang, CJ Lee, X Chen, HS Chung, D Zeng, CRH Raetz, Y Li, P Zhou, ...
Bioorganic & medicinal chemistry 19 (2), 852-860, 2011
1032011
Salmonella typhimurium impedes innate immunity with a mast-cell-suppressing protein tyrosine phosphatase, SptP
HW Choi, R Brooking-Dixon, S Neupane, CJ Lee, EA Miao, HF Staats, ...
Immunity 39 (6), 1108-1120, 2013
772013
Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation
JD Batchelor, M Doucleff, CJ Lee, K Matsubara, S De Carlo, J Heideker, ...
Journal of molecular biology 384 (5), 1058-1075, 2008
702008
The molecular mechanism of DHHC protein acyltransferases
MS Rana, CJ Lee, A Banerjee
Biochemical Society Transactions 47 (1), 157-167, 2019
682019
Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors
X Liang, CJ Lee, J Zhao, EJ Toone, P Zhou
Journal of medicinal chemistry 56 (17), 6954-6966, 2013
652013
Drug design from the cryptic inhibitor envelope
CJ Lee, X Liang, Q Wu, J Najeeb, J Zhao, R Gopalaswamy, M Titecat, ...
Nature communications 7 (1), 10638, 2016
622016
Structure and mechanism of DHHC protein acyltransferases
R Stix, CJ Lee, JD Faraldo-Gómez, A Banerjee
Journal of molecular biology 432 (18), 4983-4998, 2020
462020
Structural Basis of the Promiscuous Inhibitor Susceptibility of Escherichia coli LpxC
CJ Lee, X Liang, R Gopalaswamy, J Najeeb, ED Ark, EJ Toone, P Zhou
ACS chemical biology 9 (1), 237-246, 2014
372014
High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors
NL Marie Titecat, Xiaofei Liang, Chul-Jin Lee, Audrey Charlet, Didier ...
Journal of Antimicrobial Chemotherapy 10 (1093), 2016
34*2016
Specific interaction of the transcription elongation regulator TCERG1 with RNA polymerase II requires simultaneous phosphorylation at Ser2, Ser5, and Ser7 within the carboxyl …
J Liu, S Fan, CJ Lee, AL Greenleaf, P Zhou
Journal of Biological Chemistry 288 (15), 10890-10901, 2013
282013
Curative treatment of severe Gram-negative bacterial infections by a new class of antibiotics targeting LpxC
N Lemaître, X Liang, J Najeeb, CJ Lee, M Titecat, E Leteurtre, M Simonet, ...
MBio 8 (4), 10.1128/mbio. 00674-17, 2017
272017
In vitro reconstitution of Wnt acylation reveals structural determinants of substrate recognition by the acyltransferase human Porcupine
CJ Lee, MS Rana, C Bae, Y Li, A Banerjee
Journal of Biological Chemistry 294 (1), 231-245, 2019
242019
An extracellular histidine-containing motif in the zinc transporter ZIP4 plays a role in zinc sensing and zinc-induced endocytosis in mammalian cells
H Chun, T Korolnek, CJ Lee, HJ Coyne, DR Winge, BE Kim, MJ Petris
Journal of Biological Chemistry 294 (8), 2815-5640, 2019
192019
Structure of the essential Haemophilus influenzae UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis
J Cho, CJ Lee, J Zhao, HE Young, P Zhou
Nature microbiology 1 (11), 1-4, 2016
182016
Structure and function of the potent cyclic and linear melanocortin analogues
MK Cho, CJ Lee, CH Lee, SZ Li, SK Lim, JH Baik, W Lee
Journal of structural biology 150 (3), 300-308, 2005
162005
Bivalent recognition of fatty acyl-CoA by a human integral membrane palmitoyltransferase
CJ Lee, R Stix, MS Rana, F Shikwana, RE Murphy, R Ghirlando, ...
Proceedings of the National Academy of Sciences 119 (7), e2022050119, 2022
142022
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