| Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer AP Klein, BM Wolpin, HA Risch, RZ Stolzenberg-Solomon, E Mocci, ... Nature communications 9 (1), 556, 2018 | 224 | 2018 |
| Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif–ligand database and chemical similarity searching R Parkesh, JL Childs-Disney, M Nakamori, A Kumar, E Wang, T Wang, ... Journal of the American Chemical Society 134 (10), 4731-4742, 2012 | 146 | 2012 |
| Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive JL Childs-Disney, J Hoskins, SG Rzuczek, CA Thornton, MD Disney ACS chemical biology 7 (5), 856-862, 2012 | 136 | 2012 |
| 5-fluorouracil enhances exosome-dependent accumulation of polyadenylated rRNAs F Fang, J Hoskins, JS Butler Molecular and cellular biology, 2004 | 108 | 2004 |
| Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32. 1, 5p15. 33 and 8q24. 21 M Zhang, Z Wang, O Obazee, J Jia, EJ Childs, J Hoskins, G Figlioli, ... Oncotarget 7 (41), 66328, 2016 | 104 | 2016 |
| Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on … Z Wang, B Zhu, M Zhang, H Parikh, J Jia, CC Chung, JN Sampson, ... Human molecular genetics 23 (24), 6616-6633, 2014 | 103 | 2014 |
| Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules JL Childs-Disney, E Stepniak-Konieczna, T Tran, I Yildirim, HJ Park, ... Nature communications 4 (1), 2044, 2013 | 97 | 2013 |
| From dynamic combinatorial ‘hit’ to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy LO Ofori, J Hoskins, M Nakamori, CA Thornton, BL Miller Nucleic acids research 40 (13), 6380-6390, 2012 | 81 | 2012 |
| A transcriptome-wide association study identifies novel candidate susceptibility genes for pancreatic cancer J Zhong, A Jermusyk, L Wu, JW Hoskins, I Collins, E Mocci, M Zhang, ... JNCI: Journal of the National Cancer Institute 112 (10), 1003-1012, 2020 | 69 | 2020 |
| Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A JW Hoskins, J Jia, M Flandez, H Parikh, W Xiao, I Collins, MA Emmanuel, ... Carcinogenesis 35 (12), 2670-2678, 2014 | 64 | 2014 |
| Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects JW Hoskins, LO Ofori, CZ Chen, A Kumar, K Sobczak, M Nakamori, ... Nucleic acids research 42 (10), 6591-6602, 2014 | 62 | 2014 |
| Two high-throughput screening assays for aberrant RNA–protein interactions in myotonic dystrophy type 1 CZ Chen, K Sobczak, J Hoskins, N Southall, JJ Marugan, W Zheng, ... Analytical and bioanalytical chemistry 402, 1889-1898, 2012 | 61 | 2012 |
| CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells J Jia, AD Bosley, A Thompson, JW Hoskins, A Cheuk, I Collins, H Parikh, ... Cancer research 74 (10), 2785-2795, 2014 | 56 | 2014 |
| Properties of Nat4, an Nα-Acetyltransferase of Saccharomyces cerevisiae That Modifies N Termini of Histones H2A and H4 B Polevoda, J Hoskins, F Sherman Molecular and cellular biology 29 (11), 2913-2924, 2009 | 53 | 2009 |
| Evidence for distinct DNA‐ and RNA‐based mechanisms of 5‐fluorouracil cytotoxicity in Saccharomyces cerevisiae J Hoskins, J Scott Butler Yeast 24 (10), 861-870, 2007 | 51 | 2007 |
| Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 J Fang, J Jia, M Makowski, M Xu, Z Wang, T Zhang, JW Hoskins, J Choi, ... Nature communications 8 (1), 15034, 2017 | 49 | 2017 |
| RNA-based 5-fluorouracil toxicity requires the pseudouridylation activity of Cbf5p J Hoskins, JS Butler Genetics 179 (1), 323-330, 2008 | 49 | 2008 |
| An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer J Jia, H Parikh, W Xiao, JW Hoskins, H Pflicke, X Liu, I Collins, W Zhou, ... BMC medical genomics 6, 1-13, 2013 | 41 | 2013 |
| Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues M Zhang, S Lykke-Andersen, B Zhu, W Xiao, JW Hoskins, X Zhang, ... Gut 67 (3), 521-533, 2018 | 26 | 2018 |
| Functional characterization of a chr13q22. 1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression JW Hoskins, A Ibrahim, MA Emmanuel, SM Manmiller, Y Wu, M O’Neill, ... Human molecular genetics 25 (21), 4726-4738, 2016 | 26 | 2016 |
Laufey AmundadottirSenior Investigator, National Cancer Institute, NIHAdresse e-mail validée de mail.nih.gov
