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Manuel Llinás
Manuel Llinás
Distinguished Professor of Biochemistry & Molecular Biology, The Pennsylvania State University
Adresse e-mail validée de psu.edu - Page d'accueil
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The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum
Z Bozdech, M Llinás, BL Pulliam, ED Wong, J Zhu, JL DeRisi
PLoS biology 1 (1), e5, 2003
19632003
A transcriptional switch underlies commitment to sexual development in malaria parasites
BFC Kafsack, N Rovira-Graells, TG Clark, C Bancells, VM Crowley, ...
Nature 507 (7491), 248-252, 2014
5542014
A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium
A Sinha, KR Hughes, KK Modrzynska, TD Otto, C Pfander, NJ Dickens, ...
Nature 507 (7491), 253-257, 2014
4492014
New insights into the blood‐stage transcriptome of Plasmodium falciparum using RNA‐Seq
TD Otto, D Wilinski, S Assefa, TM Keane, LR Sarry, U Böhme, J Lemieux, ...
Molecular microbiology 76 (1), 12-24, 2010
4432010
Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains
M Llinas, Z Bozdech, ED Wong, AT Adai, JL DeRisi
Nucleic acids research 34 (4), 1166-1173, 2006
3932006
Sexual development in Plasmodium parasites: knowing when it's time to commit
GA Josling, M Llinás
Nature Reviews Microbiology 13 (9), 573-587, 2015
3472015
Host-parasite interactions revealed by Plasmodium falciparum metabolomics
KL Olszewski, JM Morrisey, D Wilinski, JM Burns, AB Vaidya, ...
Cell host & microbe 5 (2), 191-199, 2009
3162009
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS pathogens 12 (7), e1005763, 2016
2912016
Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite
TL Campbell, EK De Silva, KL Olszewski, O Elemento, M Llinás
PLoS pathogens 6 (10), e1001165, 2010
2902010
Specific DNA-binding by apicomplexan AP2 transcription factors
EK De Silva, AR Gehrke, K Olszewski, I León, JS Chahal, ML Bulyk, ...
Proceedings of the National Academy of Sciences 105 (24), 8393-8398, 2008
2872008
Solution structure of Syrian hamster prion protein rPrP (90− 231)
H Liu, S Farr-Jones, NB Ulyanov, M Llinas, S Marqusee, D Groth, ...
Biochemistry 38 (17), 5362-5377, 1999
2691999
The Apicomplexan AP2 family: integral factors regulating Plasmodium development
HJ Painter, TL Campbell, M Llinás
Molecular and biochemical parasitology 176 (1), 1-7, 2011
2372011
A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion
BI Coleman, KM Skillman, RHY Jiang, LM Childs, LM Altenhofen, ...
Cell host & microbe 16 (2), 177-186, 2014
2312014
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ...
Science 359 (6372), 191-199, 2018
2162018
Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases
J Straimer, MCS Lee, AH Lee, B Zeitler, AE Williams, JR Pearl, L Zhang, ...
Nature methods 9 (10), 993-998, 2012
2022012
Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state
SE Babbitt, L Altenhofen, SA Cobbold, ES Istvan, C Fennell, C Doerig, ...
Proceedings of the National Academy of Sciences 109 (47), E3278-E3287, 2012
1722012
Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle
H Ke, IA Lewis, JM Morrisey, KJ McLean, SM Ganesan, HJ Painter, ...
Cell reports 11 (1), 164-174, 2015
1712015
Reconstruction and flux‐balance analysis of the Plasmodium falciparum metabolic network
G Plata, TL Hsiao, KL Olszewski, M Llinás, D Vitkup
Molecular systems biology 6 (1), 408, 2010
1642010
Branched tricarboxylic acid metabolism in Plasmodium falciparum
KL Olszewski, MW Mather, JM Morrisey, BA Garcia, AB Vaidya, ...
Nature 466 (7307), 774-778, 2010
1592010
Nutrient sensing modulates malaria parasite virulence
L Mancio-Silva, K Slavic, MT Grilo Ruivo, AR Grosso, KK Modrzynska, ...
Nature 547 (7662), 213-216, 2017
1532017
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