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Bart Cuypers
Bart Cuypers
Senior Data Scientist - Immune Informatics at GSK
Adresse e-mail validée de gsk.com - Page d'accueil
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Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent
H Imamura, T Downing, F Van den Broeck, MJ Sanders, S Rijal, S Sundar, ...
Elife 5, e12613, 2016
1582016
Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression
F Dumetz, H Imamura, M Sanders, V Seblova, J Myskova, P Pescher, ...
MBio 8 (3), 10.1128/mbio. 00599-17, 2017
1472017
Genomic and Molecular Characterization of Miltefosine Resistance in Leishmania infantum Strains with Either Natural or Acquired Resistance through …
A Mondelaers, MP Sanchez-Cañete, S Hendrickx, E Eberhardt, ...
PloS one 11 (4), e0154101, 2016
992016
A community resource for paired genomic and metabolomic data mining
MA Schorn, S Verhoeven, L Ridder, F Huber, DD Acharya, AA Aksenov, ...
Nature Chemical Biology 17 (4), 363-368, 2021
982021
Relapse after treatment with miltefosine for visceral leishmaniasis is associated with increased infectivity of the infecting Leishmania donovani strain
K Rai, B Cuypers, NR Bhattarai, S Uranw, M Berg, B Ostyn, JC Dujardin, ...
MBio 4 (5), 10.1128/mbio. 00611-13, 2013
792013
Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer
LF Boullosa, J Van Loenhout, T Flieswasser, J De Waele, C Hermans, ...
Redox biology 42, 101949, 2021
722021
On the feasibility of mining CD8+ T cell receptor patterns underlying immunogenic peptide recognition
N De Neuter, W Bittremieux, C Beirnaert, B Cuypers, A Mrzic, P Moris, ...
Immunogenetics 70, 159-168, 2018
722018
Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure
M Berg, M Vanaerschot, A Jankevics, B Cuypers, I Maes, S Mukherjee, ...
Molecular microbiology 90 (2), 428-442, 2013
612013
LC-MS metabolomics from study design to data-analysis–using a versatile pathogen as a test case
M Berg, M Vanaerschot, A Jankevics, B Cuypers, R Breitling, JC Dujardin
Computational and structural biotechnology journal 4 (5), e201301002, 2013
602013
Experimental resistance to drug combinations in Leishmania donovani: metabolic and phenotypic adaptations
M Berg, R García-Hernández, B Cuypers, M Vanaerschot, JI Manzano, ...
Antimicrobial agents and chemotherapy 59 (4), 2242-2255, 2015
572015
APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin
S Uzureau, L Lecordier, P Uzureau, D Hennig, JH Graversen, F Homblé, ...
Cell Reports 30 (11), 3821-3836. e13, 2020
502020
Molecular preadaptation to antimony resistance in Leishmania donovani on the Indian Subcontinent
F Dumetz, B Cuypers, H Imamura, D Zander, E D’Haenens, I Maes, ...
MSphere 3 (2), e00548-17, 2018
482018
Gairo virus, a novel arenavirus of the widespread Mastomys natalensis: Genetically divergent, but ecologically similar to Lassa and Morogoro viruses
S Gryseels, T Rieger, L Oestereich, B Cuypers, B Borremans, R Makundi, ...
Virology 476, 249-256, 2015
472015
Macromolecular biosynthetic parameters and metabolic profile in different life stages of Leishmania braziliensis: Amastigotes as a functionally less active stage
M Jara, M Berg, G Caljon, G de Muylder, B Cuypers, D Castillo, I Maes, ...
PloS one 12 (7), e0180532, 2017
412017
Genome-Wide SNP Analysis Reveals Distinct Origins of Trypanosoma evansi and Trypanosoma equiperdum
B Cuypers, F Van den Broeck, N Van Reet, CJ Meehan, J Cauchard, ...
Genome biology and evolution 9 (8), 1990-1997, 2017
392017
Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent
B Cuypers, M Berg, H Imamura, F Dumetz, G De Muylder, ...
Infection, Genetics and Evolution 62, 170-178, 2018
372018
Multiplexed Spliced-Leader Sequencing: A high-throughput, selective method for RNA-seq in Trypanosomatids
B Cuypers, MA Domagalska, P Meysman, G Muylder, M Vanaerschot, ...
Scientific reports 7 (1), 3725, 2017
342017
Ferroptosis Induction in Multiple Myeloma Cells Triggers DNA Methylation and Histone Modification Changes Associated with Cellular Senescence
E Logie, B Van Puyvelde, B Cuypers, A Schepers, H Berghmans, ...
International Journal of Molecular Sciences 22 (22), 12234, 2021
262021
Nanopore Sequencing for Mycobacterium tuberculosis: a Critical Review of the Literature, New Developments, and Future Opportunities
A Dippenaar, SN Goossens, M Grobbelaar, S Oostvogels, B Cuypers, ...
Journal of Clinical Microbiology 60 (1), e00646-21, 2022
242022
Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq
BV Krivoshiev, GTS Beemster, K Sprangers, B Cuypers, K Laukens, ...
Toxicology in Vitro 46, 178-188, 2018
212018
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