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Keith Thompson
Keith Thompson
Principal Scientist
Verified email at ucb.com
Title
Cited by
Cited by
Year
Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates
JE Dunford, K Thompson, FP Coxon, SP Luckman, FM Hahn, CD Poulter, ...
Journal of Pharmacology and Experimental Therapeutics 296 (2), 235-242, 2001
12082001
Molecular mechanisms of action of bisphosphonates: current status
AJ Roelofs, K Thompson, S Gordon, MJ Rogers
Clinical Cancer Research 12 (20), 6222s-6230s, 2006
7332006
Recent advances in understanding the mechanism of action of bisphosphonates
FP Coxon, K Thompson, MJ Rogers
Current opinion in pharmacology 6 (3), 307-312, 2006
3502006
Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP
AJ Roelofs, M Jauhiainen, H Mönkkönen, MJ Rogers, J Mönkkönen, ...
British journal of haematology 144 (2), 245-250, 2009
3232009
Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosis
K Thompson, MJ Rogers, FP Coxon, JC Crockett
Molecular pharmacology 69 (5), 1624-1632, 2006
2992006
Statins prevent bisphosphonate‐induced γ, δ‐T‐cell proliferation and activation in vitro
K Thompson, MJ Rogers
Journal of Bone and Mineral Research 19 (2), 278-288, 2004
2922004
Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells
FP Coxon, K Thompson, AJ Roelofs, FH Ebetino, MJ Rogers
Bone 42 (5), 848-860, 2008
2842008
Bisphosphonates: molecular mechanisms of action and effects on bone cells, monocytes and macrophages
A J Roelofs, K Thompson, F H Ebetino, M J Rogers, F P Coxon
Current pharmaceutical design 16 (27), 2950-2960, 2010
2382010
Pathogenic Mechanisms and Host Interactions in Staphylococcus epidermidis Device-Related Infection
M Sabaté Brescó, LG Harris, K Thompson, B Stanic, M Morgenstern, ...
Frontiers in microbiology 8, 1401, 2017
2162017
Functional biomaterials for bone regeneration: a lesson in complex biology
AR Armiento, LP Hatt, G Sanchez Rosenberg, K Thompson, MJ Stoddart
Advanced Functional Materials 30 (44), 1909874, 2020
1542020
Alkylamines cause Vγ9Vδ2 T-cell activation and proliferation by inhibiting the mevalonate pathway
K Thompson, J Rojas-Navea, MJ Rogers
Blood 107 (2), 651-654, 2006
1292006
A global benchmark study using affinity-based biosensors
RL Rich, GA Papalia, PJ Flynn, J Furneisen, J Quinn, JS Klein, ...
Analytical biochemistry 386 (2), 194-216, 2009
1232009
IL-23 inhibits osteoclastogenesis indirectly through lymphocytes and is required for the maintenance of bone mass in mice
JMW Quinn, NA Sims, H Saleh, D Mirosa, K Thompson, S Bouralexis, ...
The Journal of Immunology 181 (8), 5720-5729, 2008
1032008
Activation of γδ T cells by bisphosphonates
K Thompson, AJ Roelofs, M Jauhiainen, H Mönkkönen, J Mönkkönen, ...
Osteoimmunology: Interactions of the Immune and skeletal systems II, 11-20, 2010
872010
Current concepts of osteomyelitis: from pathological mechanisms to advanced research methods.
MI Hofstee, G Muthukrishnan, GJ Atkins, M Riool, K Thompson, ...
The American Journal of Pathology 190 (6), 1151-1163, 2020
862020
Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase
K Thompson, JE Dunford, FH Ebetino, MJ Rogers
Biochemical and biophysical research communications 290 (2), 869-873, 2002
742002
The effect of krill oil supplementation on exercise performance and markers of immune function
M Da Boit, I Mastalurova, G Brazaite, N McGovern, K Thompson, SR Gray
Plos one 10 (9), e0139174, 2015
372015
Fluvastatin does not prevent the acute-phase response to intravenous zoledronic acid in post-menopausal women
K Thompson, F Keech, DJ McLernon, K Vinod, RJ May, WG Simpson, ...
Bone 49 (1), 140-145, 2011
352011
Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro
A Pappalardo, K Thompson
Clinical & Experimental Immunology 174 (2), 281-291, 2013
342013
Development of bone seeker–functionalised microspheres as a targeted local antibiotic delivery system for bone infections
SG Rotman, K Thompson, DW Grijpma, RG Richards, TF Moriarty, D Eglin, ...
Journal of orthopaedic translation 21, 136-145, 2020
312020
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Articles 1–20