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Mans Broekgaarden
Mans Broekgaarden
Affiliation inconnue
Adresse e-mail validée de mgh.harvard.edu
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Année
The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer
M Heger, RF van Golen, M Broekgaarden, MC Michel
Pharmacological reviews 66 (1), 222-307, 2014
5702014
Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies
M Broekgaarden, R Weijer, TM van Gulik, MR Hamblin, M Heger
Cancer and Metastasis Reviews 34, 643-690, 2015
2332015
Photonanomedicine: a convergence of photodynamic therapy and nanotechnology
G Obaid, M Broekgaarden, AL Bulin, HC Huang, J Kuriakose, J Liu, ...
Nanoscale 8 (25), 12471-12503, 2016
1852016
Enhancing photodynamic therapy of refractory solid cancers: Combining second-generation photosensitizers with multi-targeted liposomal delivery
R Weijer, M Broekgaarden, M Kos, R van Vught, EAJ Rauws, E Breukink, ...
Journal of Photochemistry and Photobiology C: Photochemistry Reviews 23, 103-131, 2015
1422015
Microbial production of natural raspberry ketone
J Beekwilder, IM Van der Meer, O Sibbesen, M Broekgaarden, I Qvist, ...
Biotechnology Journal: Healthcare Nutrition Technology 2 (10), 1270-1279, 2007
1302007
Inhibition of hypoxia-inducible factor 1 with acriflavine sensitizes hypoxic tumor cells to photodynamic therapy with zinc phthalocyanine-encapsulating cationic liposomes
M Broekgaarden, R Weijer, M Krekorian, B van den IJssel, M Kos, ...
Nano Research, 1-24, 2016
862016
Preparation and practical applications of 2′, 7′-dichlorodihydrofluorescein in redox assays
MJ Reiniers, RF van Golen, S Bonnet, M Broekgaarden, TM van Gulik, ...
Analytical chemistry 89 (7), 3853-3857, 2017
802017
Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates …
G Obaid, S Bano, S Mallidi, M Broekgaarden, J Kuriakose, Z Silber, ...
Nano letters 19 (11), 7573-7587, 2019
742019
An overview of three promising mechanical, optical, and biochemical engineering approaches to improve selective photothermolysis of refractory port wine stains
G Aguilar, B Choi, M Broekgaarden, O Yang, B Yang, P Ghasri, JK Chen, ...
Annals of biomedical engineering 40, 486-506, 2012
742012
Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy
R Weijer, M Broekgaarden, M Krekorian, LK Alles, AC van Wijk, ...
Oncotarget 7 (3), 3341, 2016
662016
Development and in vitro proof-of-concept of interstitially targeted zinc-phthalocyanine liposomes for photodynamic therapy
M Broekgaarden, A IPM de Kroon, T M van Gulik, M Heger
Current medicinal chemistry 21 (3), 377-391, 2014
652014
Modulation of redox metabolism negates cancer-associated fibroblasts-induced treatment resistance in a heterotypic 3D culture platform of pancreatic cancer
M Broekgaarden, S Anbil, AL Bulin, G Obaid, Z Mai, Y Baglo, I Rizvi, ...
Biomaterials 222, 119421, 2019
602019
Comprehensive high-throughput image analysis for therapeutic efficacy of architecturally complex heterotypic organoids
AL Bulin, M Broekgaarden, T Hasan
Scientific reports 7 (1), 16645, 2017
552017
Radiation dose‐enhancement is a potent radiotherapeutic effect of rare‐earth composite nanoscintillators in preclinical models of glioblastoma
AL Bulin, M Broekgaarden, F Chaput, V Baisamy, J Garrevoet, B Busser, ...
Advanced Science 7 (20), 2001675, 2020
502020
Photodynamic therapy with liposomal zinc phthalocyanine and tirapazamine increases tumor cell death via DNA damage
M Broekgaarden, R Weijer, AC van Wijk, RC Cox, MR Egmond, R Hoebe, ...
Journal of biomedical nanotechnology 13 (2), 204-220, 2017
482017
Site-specific conjugation of single domain antibodies to liposomes enhances photosensitizer uptake and photodynamic therapy efficacy
M Broekgaarden, R Van Vught, S Oliveira, RC Roovers, ...
Nanoscale 8 (12), 6490-6494, 2016
432016
Neoadjuvant photodynamic therapy augments immediate and prolonged oxaliplatin efficacy in metastatic pancreatic cancer organoids
M Broekgaarden, I Rizvi, AL Bulin, L Petrovic, R Goldschmidt, I Massodi, ...
Oncotarget 9 (16), 13009, 2018
382018
Low dose photodynamic therapy harmonizes with radiation therapy to induce beneficial effects on pancreatic heterocellular spheroids
AL Bulin, M Broekgaarden, D Simeone, T Hasan
Oncotarget 10 (27), 2625, 2019
352019
Vitamin D receptor activation and photodynamic priming enables durable low-dose chemotherapy
S Anbil, M Pigula, HC Huang, S Mallidi, M Broekgaarden, Y Baglo, ...
Molecular cancer therapeutics 19 (6), 1308-1319, 2020
342020
Endovascular laser–tissue interactions and biological responses in relation to endovenous laser therapy
M Heger, RF van Golen, M Broekgaarden, RR van den Bos, ...
Lasers in medical science 29, 405-422, 2014
342014
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