Suivre
Alexandra Surcel
Alexandra Surcel
Department of Cell Biology, Johns Hopkins School of Medicine
Adresse e-mail validée de jhmi.edu
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Année
Entosis is induced by glucose starvation
JC Hamann, A Surcel, R Chen, C Teragawa, JG Albeck, DN Robinson, ...
Cell reports 20 (1), 201-210, 2017
1572017
14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis
Q Zhou, YS Kee, CC Poirier, C Jelinek, J Osborne, S Divi, A Surcel, ...
Current Biology 20 (21), 1881-1889, 2010
992010
Pharmacological activation of myosin II paralogs to correct cell mechanics defects
A Surcel, WP Ng, H West-Foyle, Q Zhu, Y Ren, LB Avery, AK Krenc, ...
Proceedings of the National Academy of Sciences 112 (5), 1428-1433, 2015
682015
Targeting mechanoresponsive proteins in pancreatic cancer: 4-hydroxyacetophenone blocks dissemination and invasion by activating MYH14
A Surcel, ES Schiffhauer, DG Thomas, Q Zhu, K DiNapoli, M Herbig, ...
Biophysical Journal 116 (3), 260a, 2019
592019
Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization
H Bai, Q Zhu, A Surcel, T Luo, Y Ren, B Guan, Y Liu, N Wu, NE Joseph, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 311 (3 …, 2016
422016
Cytokinesis through biochemical–mechanical feedback loops
A Surcel, YS Kee, T Luo, DN Robinson
Seminars in cell & developmental biology 21 (9), 866-873, 2010
402010
4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis
DS Bryan, M Stack, K Krysztofiak, U Cichoń, DG Thomas, A Surcel, ...
Proceedings of the National Academy of Sciences 117 (36), 22423-22429, 2020
322020
Cohesin interaction with centromeric minichromosomes shows a multi-complex rod-shaped structure
A Surcel, D Koshland, H Ma, RT Simpson
PLoS One 3 (6), e2453, 2008
272008
7.5 Understanding how dividing cells change shape
DN Robinson, YS Kee, T Luo, A Surcel
Comprehensive Biophysics. Amsterdam: Elsevier, 48-72, 2012
262012
Genetic suppression of a phosphomimic myosin II identifies system-level factors that promote myosin II cleavage furrow accumulation
Y Ren, H West-Foyle, A Surcel, C Miller, DN Robinson
Molecular biology of the cell 25 (25), 4150-4165, 2014
192014
Comprehensive Biophysics
DN Robinson, YS Kee, T Luo, A Surcel, EH Egelman
Academic 7, 48-73, 2012
172012
The mechanobiome: a goldmine for cancer therapeutics
E Parajón, A Surcel, DN Robinson
American Journal of Physiology-Cell Physiology 320 (3), C306-C323, 2021
152021
Long-term maintenance of stable copy number in the eukaryotic SMC family: origin of a vertebrate meiotic SMC1 and fate of recent segmental duplicates
A Surcel, X Zhou, L Quan, H Ma
Journal of Systematics and Evolution 46 (3), 405-423, 2008
102008
Meddling with myosin’s mechanobiology in cancer
A Surcel, DN Robinson
Proceedings of the National Academy of Sciences 116 (31), 15322-15323, 2019
82019
Harnessing the adaptive potential of mechanoresponsive proteins to overwhelm pancreatic cancer dissemination and invasion
A Surcel, E Schiffhauer, D Thomas, Q Zhu, K DiNapoli, M Herbig, O Otto, ...
BioRxiv, 190553, 2017
72017
Treating and preventing diseases by modulating cell mechanics
D Robinson, A Surcel, WP Ng, CLF Meyers
US Patent 11,834,401, 2023
2023
Treating and preventing diseases by modulating cell mechanics
D Robinson, A Surcel, WP Ng, CLF Meyers
US Patent 10,787,410, 2020
2020
4-Hydroxyacetophenone Modulates the Cytoskeleton through Nonmuscle Myosin-2C to Reduce Metastasis
D Bryan, M Stack, K Krysztofiak, U Cichoń, D Thomas, A Surcel, ...
Biophysical Journal 116 (3), 548a, 2019
2019
Computer Aided Small Molecule Modulation of Pancreatic Cancer Mechanobiology
KT DiNapoli, E Schiffhauer, A Surcel, D Thomas, P Iglesias, D Robinson
Biophysical Journal 116 (3), 415a, 2019
2019
The mechanobiome of pancreatic cancer: a viable, targetable drug space
A Surcel, ES Schiffhauer, D Thomas, Q Zhu, R Anders, D Robinson
Cancer Research 77 (13_Supplement), 901-901, 2017
2017
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