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Zachary Berndsen
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Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
Y Watanabe, ZT Berndsen, J Raghwani, GE Seabright, JD Allen, ...
Nature communications 11 (1), 2688, 2020
3422020
Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows
D Sok, KM Le, M Vadnais, KL Saye-Francisco, JG Jardine, JL Torres, ...
Nature 548 (7665), 108-111, 2017
1702017
Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle
PJM Brouwer, A Antanasijevic, Z Berndsen, A Yasmeen, B Fiala, TPL Bijl, ...
Nature Communications 10 (1), 4272, 2019
1522019
Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer
L Cao, M Pauthner, R Andrabi, K Rantalainen, Z Berndsen, JK Diedrich, ...
Nature communications 9 (1), 3693, 2018
1262018
HIV envelope glycoform heterogeneity and localized diversity govern the initiation and maturation of a V2 apex broadly neutralizing antibody lineage
E Landais, B Murrell, B Briney, S Murrell, K Rantalainen, ZT Berndsen, ...
Immunity 47 (5), 990-1003. e9, 2017
932017
Nonequilibrium dynamics and ultraslow relaxation of confined DNA during viral packaging
ZT Berndsen, N Keller, S Grimes, PJ Jardine, DE Smith
Proceedings of the National Academy of Sciences 111 (23), 8345-8350, 2014
932014
Visualization of the HIV-1 Env glycan shield across scales
ZT Berndsen, S Chakraborty, X Wang, CA Cottrell, JL Torres, JK Diedrich, ...
Proceedings of the National Academy of Sciences 117 (45), 28014-28025, 2020
642020
HIV-1 envelope and MPER antibody structures in lipid assemblies
K Rantalainen, ZT Berndsen, A Antanasijevic, T Schiffner, X Zhang, ...
Cell Reports 31 (4), 2020
622020
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens
A Antanasijevic, G Ueda, PJM Brouwer, J Copps, D Huang, JD Allen, ...
PLoS Pathogens 16 (8), e1008665, 2020
552020
Co-evolution of HIV envelope and apex-targeting neutralizing antibody lineage provides benchmarks for vaccine design
K Rantalainen, ZT Berndsen, S Murrell, L Cao, O Omorodion, JL Torres, ...
Cell reports 23 (11), 3249-3261, 2018
512018
Structural basis of broad HIV neutralization by a vaccine-induced cow antibody
RL Stanfield, ZT Berndsen, R Huang, D Sok, G Warner, JL Torres, ...
Science advances 6 (22), eaba0468, 2020
342020
Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM
A Antanasijevic, LM Sewall, CA Cottrell, DG Carnathan, LE Jimenez, ...
Nature communications 12 (1), 4817, 2021
332021
Continuous allosteric regulation of a viral packaging motor by a sensor that detects the density and conformation of packaged DNA
ZT Berndsen, N Keller, DE Smith
Biophysical journal 108 (2), 315-324, 2015
252015
EMHP: an accurate automated hole masking algorithm for single-particle cryo-EM image processing
Z Berndsen, C Bowman, H Jang, AB Ward
Bioinformatics 33 (23), 3824-3826, 2017
212017
Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIVsmm/mac Envelope Glycoprotein Uncouple Antibody-Dependent Cellular …
B von Bredow, R Andrabi, M Grunst, AG Grandea III, K Le, G Song, ...
MBio 10 (4), 10.1128/mbio. 01255-19, 2019
192019
Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
JR Willis, ZT Berndsen, KM Ma, JM Steichen, T Schiffner, E Landais, ...
Immunity 55 (11), 2149-2167. e9, 2022
172022
Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice
E Melzi, JR Willis, KM Ma, YC Lin, S Kratochvil, ZT Berndsen, EA Landais, ...
Immunity 55 (11), 2168-2186. e6, 2022
132022
Quantification of the resilience and vulnerability of HIV-1 native glycan shield at atomistic detail
S Chakraborty, ZT Berndsen, NW Hengartner, BT Korber, AB Ward, ...
IScience 23 (12), 2020
112020
Experimental comparison of forces resisting viral DNA packaging and driving DNA ejection
N Keller, ZT Berndsen, PJ Jardine, DE Smith
Physical Review E 95 (5), 052408, 2017
92017
Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus
F Zhao, ZT Berndsen, N Pedreño-Lopez, A Burns, JD Allen, S Barman, ...
Nature communications 13 (1), 5236, 2022
32022
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