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Lawrence J Williams
Lawrence J Williams
Professor of Chemistry, Rutgers University
Adresse e-mail validée de chem.rutgers.edu - Page d'accueil
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The reaction of thio acids with azides: a new mechanism and new synthetic applications
N Shangguan, S Katukojvala, R Greenberg, LJ Williams
Journal of the American Chemical Society 125 (26), 7754-7755, 2003
3982003
Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial
T Gilewski, G Ragupathi, S Bhuta, LJ Williams, C Musselli, XF Zhang, ...
Proceedings of the National Academy of Sciences 98 (6), 3270-3275, 2001
2712001
Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains
DM Coltart, AK Royyuru, LJ Williams, PW Glunz, D Sames, SD Kuduk, ...
Journal of the American Chemical Society 124 (33), 9833-9844, 2002
2122002
Mechanism of thio acid/azide amidation
RV Kolakowski, N Shangguan, RR Sauers, LJ Williams
Journal of the American Chemical Society 128 (17), 5695-5702, 2006
2032006
Selective inhibition of human brain tumor cell proliferation via multifunctional quantum dot-based siRNA delivery
J Jung, A Solanki, KA Memoli, K Kamei, H Kim, MA Drahl, LJ Williams, ...
Angewandte Chemie (International ed. in English) 49 (1), 103, 2010
1902010
Toward optimized carbohydrate-based anticancer vaccines: Epitope clustering, carrier structure, and adjuvant all influence antibody responses to Lewisy conjugates in mice
V Kudryashov, PW Glunz, LJ Williams, S Hintermann, SJ Danishefsky, ...
Proceedings of the National Academy of Sciences 98 (6), 3264-3269, 2001
1552001
On the power of chemical synthesis: immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines
G Ragupathi, DM Coltart, LJ Williams, F Koide, E Kagan, J Allen, C Harris, ...
Proceedings of the National Academy of Sciences 99 (21), 13699-13704, 2002
1512002
Induction of antibodies against GM2 ganglioside by immunizing melanoma patients using GM2-keyhole limpet hemocyanin+ QS21 vaccine: a dose-response study
PB Chapman, DM Morrissey, KS Panageas, WB Hamilton, C Zhan, ...
Clinical Cancer Research 6 (3), 874-879, 2000
1262000
C C Fragmentation: Origins and Recent Applications
MA Drahl, M Manpadi, LJ Williams
Angewandte Chemie International Edition 52 (43), 11222-11251, 2013
1022013
A formal synthesis of psymberin
N Shangguan, S Kiren, LJ Williams
Organic letters 9 (6), 1093-1096, 2007
932007
A Second Generation Synthesis of the MBr1 (Globo‐H) Breast Tumor Antigen: New Application of the n‐Pentenyl Glycoside Method for Achieving Complex …
JR Allen, JG Allen, XF Zhang, LJ Williams, A Zatorski, G Ragupathi, ...
Chemistry–A European Journal 6 (8), 1366-1375, 2000
872000
Probing cell-surface architecture through synthesis: an NMR-determined structural motif for tumor-associated mucins
DH Live, LJ Williams, SD Kuduk, JB Schwarz, PW Glunz, XT Chen, ...
Proceedings of the National Academy of Sciences 96 (7), 3489-3493, 1999
861999
Design and synthesis of Ley-bearing glycopeptides that mimic cell surface Ley mucin glycoprotein architecture
PW Glunz, S Hintermann, LJ Williams, JB Schwarz, SD Kuduk, ...
Journal of the American Chemical Society 122 (30), 7273-7279, 2000
842000
Recent developments in allene-based synthetic methods.
H Kim, LJ Williams
Current Opinion in Drug Discovery & Development 11 (6), 870-894, 2008
812008
Thio acid/azide amidation: An improved route to N-acyl sulfonamides
KN Barlett, RV Kolakowski, S Katukojvala, LJ Williams
Organic letters 8 (5), 823-826, 2006
792006
Polyclonal antibodies from patients immunized with a globo H-keyhole limpet hemocyanin vaccine: isolation, quantification, and characterization of immune responses by using …
ZG Wang, LJ Williams, XF Zhang, A Zatorski, V Kudryashov, G Ragupathi, ...
Proceedings of the National Academy of Sciences 97 (6), 2719-2724, 2000
752000
Trimeric antigenic O-linked glycopeptide conjugates, methods of preparation and uses thereof
S Danishefsky, D Sames, S Hintermann, X Chen, J Schwarz, P Glunz, ...
US Patent App. 10/600,012, 2004
692004
Spirodiepoxides in total synthesis: epoxomicin
S Katukojvala, KN Barlett, SD Lotesta, LJ Williams
Journal of the American Chemical Society 126 (47), 15348-15349, 2004
672004
Allene Synthesis via C− C Fragmentation: Method and Mechanistic Insight
RV Kolakowski, M Manpadi, Y Zhang, TJ Emge, LJ Williams
Journal of the American Chemical Society 131 (36), 12910-12911, 2009
612009
A Spirodiepoxide-Based Strategy to the A− B Ring System of Pectenotoxin 4
SD Lotesta, Y Hou, LJ Williams
Organic letters 9 (5), 869-872, 2007
572007
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