| Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates E van Beek, E Pieterman, L Cohen, C Löwik, S Papapoulos Biochemical and biophysical research communications 264 (1), 108-111, 1999 | 655 | 1999 |
| Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT‐1 pathway between rheumatoid tissues TCTM van der Pouw Kraan, FA van Gaalen, PV Kasperkovitz, NL Verbeet, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 308 | 2003 |
| Invasive properties of fibroblast-like synoviocytes: correlation with growth characteristics and expression of MMP-1, MMP-3, and MMP-10 TCA Tolboom, E Pieterman, WH Van der Laan, REM Toes, ... Annals of the rheumatic diseases 61 (11), 975-980, 2002 | 290 | 2002 |
| Nitrogen-Containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their … E van Beek, E Pieterman, L Cohen, C Löwik, S Papapoulos Biochemical and biophysical research communications 255 (2), 491-494, 1999 | 270 | 1999 |
| Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin [S] S Kühnast, JWA van der Hoorn, EJ Pieterman, AM van den Hoek, ... Journal of lipid research 55 (10), 2103-2112, 2014 | 228 | 2014 |
| The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE* 3Leiden. CETP mice C Landlinger, MG Pouwer, C Juno, JWA van der Hoorn, EJ Pieterman, ... European heart journal 38 (32), 2499-2507, 2017 | 217 | 2017 |
| Discovery of distinctive gene expression profiles in rheumatoid synovium using cDNA microarray technology: evidence for the existence of multiple pathways of tissue destruction … T Van der Pouw Kraan, FA Van Gaalen, TWJ Huizinga, E Pieterman, ... Genes & Immunity 4 (3), 187-196, 2003 | 175 | 2003 |
| Fibroblast‐like synoviocytes derived from patients with rheumatoid arthritis show the imprint of synovial tissue heterogeneity: evidence of a link between an increased … PV Kasperkovitz, TCG Timmer, TJ Smeets, NL Verbeet, PP Tak, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2005 | 173 | 2005 |
| Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3 WH Van der Laan, PHA Quax, CA Seemayer, LGM Huisman, ... Gene therapy 10 (3), 234-242, 2003 | 152 | 2003 |
| Perfluoroalkyl sulfonates cause alkyl chain length–dependent hepatic steatosis and hypolipidemia mainly by impairing lipoprotein production in APOE* 3-Leiden CETP mice S Bijland, PCN Rensen, EJ Pieterman, ACE Maas, JW van der Hoorn, ... Toxicological Sciences 123 (1), 290-303, 2011 | 148 | 2011 |
| Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE* 3Leiden. CETP mice—a translational model for atherosclerosis LM Gierman, S Kühnast, A Koudijs, EJ Pieterman, M Kloppenburg, ... Annals of the rheumatic diseases 73 (5), 921-927, 2014 | 101 | 2014 |
| Association of the–2849 interleukin‐10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis LR Lard, FA Van Gaalen, JJM Schonkeren, EJ Pieterman, G Stoeken, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 101 | 2003 |
| Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin S Kühnast, SJL van der Tuin, JWA van der Hoorn, JB van Klinken, B Simic, ... European heart journal 36 (1), 39-50, 2015 | 91 | 2015 |
| Inhibitors of prenylation of Ras and other G-proteins and their application as therapeutics LH Cohen, E Pieterman, REW van Leeuwen, M Overhand, BEA Burm, ... Biochemical pharmacology 60 (8), 1061-1068, 2000 | 81 | 2000 |
| PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE [S] B Ason, JWA van der Hoorn, J Chan, E Lee, EJ Pieterman, KK Nguyen, ... Journal of lipid research 55 (11), 2370-2379, 2014 | 73 | 2014 |
| Six microsatellite markers on the short arm of chromosome 6 in relation to HLA-DR3 and TNF− 308A in systemic lupus erythematosus MW Van Der Linden, AR Van Der Slik, E Zanelli, MJ Giphart, E Pieterman, ... Genes & Immunity 2 (7), 373-380, 2001 | 69 | 2001 |
| APOE* 3Leiden. CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome AM van den Hoek, JWA van der Hoorn, AC Maas, RM van den Hoogen, ... Diabetes, Obesity and Metabolism 16 (6), 537-544, 2014 | 66 | 2014 |
| Infection efficiency of type 5 adenoviral vectors in synovial tissue can be enhanced with a type 16 fiber PH Goossens, MJE Havenga, E Pieterman, AA Lemckert, FC Breedveld, ... Arthritis & Rheumatism 44 (3), 570-577, 2001 | 62 | 2001 |
| The BCR-ABL1 inhibitors imatinib and ponatinib decrease plasma cholesterol and atherosclerosis, and nilotinib and ponatinib activate coagulation in a translational mouse model MG Pouwer, EJ Pieterman, L Verschuren, MPM Caspers, C Kluft, ... Frontiers in cardiovascular medicine 5, 55, 2018 | 59 | 2018 |
| Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE∗ 3Leiden mice MC Morrison, W Liang, P Mulder, L Verschuren, E Pieterman, K Toet, ... Journal of hepatology 62 (5), 1180-1186, 2015 | 59 | 2015 |
