Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7379 | 2014 |
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology A Zimprich, S Biskup, P Leitner, P Lichtner, M Farrer, S Lincoln, ... Neuron 44 (4), 601-607, 2004 | 3407 | 2004 |
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ... Nature genetics 50 (5), 668-681, 2018 | 2508 | 2018 |
Genome-wide association study identifies 30 loci associated with bipolar disorder EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ... Nature genetics 51 (5), 793-803, 2019 | 1375 | 2019 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1367 | 2018 |
Modeling linkage disequilibrium increases accuracy of polygenic risk scores BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ... The american journal of human genetics 97 (4), 576-592, 2015 | 1305 | 2015 |
Large-scale genotyping identifies 41 new loci associated with breast cancer risk K Michailidou, P Hall, A Gonzalez-Neira, M Ghoussaini, J Dennis, ... Nature genetics 45 (4), 353-361, 2013 | 1261 | 2013 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1132 | 2022 |
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment EB Binder, D Salyakina, P Lichtner, GM Wochnik, M Ising, B Pütz, ... Nature genetics 36 (12), 1319-1325, 2004 | 1118 | 2004 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 1035 | 2019 |
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene A Meindl, H Hellebrand, C Wiek, V Erven, B Wappenschmidt, ... Nature genetics 42 (5), 410-414, 2010 | 918 | 2010 |
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects CR Marshall, DP Howrigan, D Merico, B Thiruvahindrapuram, W Wu, ... Nature genetics 49 (1), 27-35, 2017 | 913 | 2017 |
Common genetic variants influence human subcortical brain structures DP Hibar, JL Stein, ME Renteria, A Arias-Vasquez, S Desrivières, ... Nature 520 (7546), 224-229, 2015 | 835 | 2015 |
Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions J Winkelmann, B Schormair, P Lichtner, S Ripke, L Xiong, S Jalilzadeh, ... Nature genetics 39 (8), 1000-1006, 2007 | 773 | 2007 |
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ... Nature genetics 45 (9), 984-994, 2013 | 753 | 2013 |
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ... Nature genetics 53 (6), 817-829, 2021 | 736 | 2021 |
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine P Gormley, V Anttila, BS Winsvold, P Palta, T Esko, TH Pers, KH Farh, ... Nature genetics 48 (8), 856-866, 2016 | 723 | 2016 |
Identification of common variants associated with human hippocampal and intracranial volumes JL Stein, SE Medland, AA Vasquez, DP Hibar, RE Senstad, AM Winkler, ... Nature genetics 44 (5), 552-561, 2012 | 698 | 2012 |
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data PM Thompson, JL Stein, SE Medland, DP Hibar, AA Vasquez, ... Brain imaging and behavior 8, 153-182, 2014 | 664 | 2014 |
A susceptibility locus for Parkinson's disease maps to chromosome 2p13 T Gasser, B Müller-Myhsok, ZK Wszolek, R Oehlmann, DB Calne, ... Nature genetics 18 (3), 262-265, 1998 | 648 | 1998 |