Richard I. Morimoto
Richard I. Morimoto
Bill and Gayle Cook Professor of Biology, Dept of Molecular Biosciences, Northwestern
Adresse e-mail validée de northwestern.edu - Page d'accueil
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Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
RI Morimoto
Genes & development 12 (24), 3788-3796, 1998
20321998
Adapting proteostasis for disease intervention
WE Balch, RI Morimoto, A Dillin, JW Kelly
science 319 (5865), 916-919, 2008
19622008
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
HM Beere, BB Wolf, K Cain, DD Mosser, A Mahboubi, T Kuwana, P Tailor, ...
Nature cell biology 2 (8), 469-475, 2000
17152000
Cells in stress: transcriptional activation of heat shock genes
RI Morimoto
SCIENCE-NEW YORK THEN WASHINGTON- 259, 1409-1409, 1993
16061993
The biology of heat shock proteins and molecular chaperones
RI Morimoto, A Tissières
1210*1994
Role of the heat shock response and molecular chaperones in oncogenesis and cell death
C Jolly, RI Morimoto
Journal of the National Cancer Institute 92 (19), 1564-1572, 2000
11762000
Heat shock factors: integrators of cell stress, development and lifespan
M Åkerfelt, RI Morimoto, L Sistonen
Nature reviews Molecular cell biology 11 (8), 545-555, 2010
11192010
Biological and chemical approaches to diseases of proteostasis deficiency
ET Powers, RI Morimoto, A Dillin, JW Kelly, WE Balch
Annual review of biochemistry 78, 959-991, 2009
10262009
Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the …
KD Sarge, SP Murphy, RI Morimoto
Molecular and cellular biology 13 (3), 1392-1407, 1993
9681993
Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70
C Hunt, RI Morimoto
Proceedings of the National Academy of Sciences 82 (19), 6455-6459, 1985
9651985
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
RI Morimoto
Genes & development 22 (11), 1427-1438, 2008
8732008
The chaperone function of hsp70 is required for protection against stress-induced apoptosis
DD Mosser, AW Caron, L Bourget, AB Meriin, MY Sherman, RI Morimoto, ...
Molecular and cellular biology 20 (19), 7146-7159, 2000
8172000
Geroscience: linking aging to chronic disease
BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ...
Cell 159 (4), 709-713, 2014
7612014
Chaperoning signaling pathways: molecular chaperones as stress-sensingheat shock'proteins
EAA Nollen, RI Morimoto
Journal of cell science 115 (14), 2809-2816, 2002
7472002
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
JF Morley, HR Brignull, JJ Weyers, RI Morimoto
Proceedings of the National Academy of Sciences 99 (16), 10417-10422, 2002
7322002
Regulation of Longevity in Caenorhabditis elegans by Heat Shock Factor and Molecular Chaperones
JF Morley, RI Morimoto
Molecular biology of the cell 15 (2), 657-664, 2004
6922004
Stress proteins in biology and medicine
RI Morimoto, A Tissières, C Georgopoulos
Cold Spring Harbor Laboratory, 1990
6771990
Molecularchaperones as HSF1-specific transcriptional repressors
Y Shi, DD Mosser, RI Morimoto
Genes & development 12 (5), 654-666, 1998
6671998
Stress–inducible responses and heat shock proteins: new pharmacologic targets for cytoprotection
RI Morimoto, MG Santoro
Nature biotechnology 16 (9), 833-838, 1998
6661998
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development
X Shen, RE Ellis, K Lee, CY Liu, K Yang, A Solomon, H Yoshida, ...
Cell 107 (7), 893-903, 2001
6622001
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