Suivre
sylvain Ladame
sylvain Ladame
Lecturer in Biosensor Development, Department of Bioengineering, Imperial College London
Adresse e-mail validée de imperial.ac.uk
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Putative DNA Quadruplex Formation within the Human c-kit Oncogene
S Rankin, AP Reszka, J Huppert, M Zloh, GN Parkinson, AK Todd, ...
Journal of the American Chemical Society 127 (30), 10584-10589, 2005
6522005
A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene
H Fernando, AP Reszka, J Huppert, S Ladame, S Rankin, ...
Biochemistry 45 (25), 7854-7860, 2006
4602006
Dynamic combinatorial chemistry: on the road to fulfilling the promise
S Ladame
Organic & Biomolecular Chemistry 6 (2), 219-226, 2008
2842008
Enhanced chemical synthesis at soft interfaces: A universal reaction-adsorption mechanism in microcompartments
A Fallah-Araghi, K Meguellati, JC Baret, A El Harrak, T Mangeat, ...
Physical Review Letters 112 (2), 028301, 2014
2482014
Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands
PS Shirude, ER Gillies, S Ladame, F Godde, K Shin-Ya, I Huc, ...
Journal of the American Chemical Society 129 (39), 11890-11891, 2007
1952007
Hydrogel-coated microneedle arrays for minimally invasive sampling and sensing of specific circulating nucleic acids from skin interstitial fluid
D Al Sulaiman, JYH Chang, NR Bennett, H Topouzi, CA Higgins, DJ Irvine, ...
ACS nano 13 (8), 9620-9628, 2019
1512019
Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands
K Jantos, R Rodriguez, S Ladame, PS Shirude, S Balasubramanian
Journal of the American Chemical Society 128 (42), 13662-13663, 2006
1442006
DNA‐templated synthesis of trimethine cyanine dyes: a versatile fluorogenic reaction for sensing G‐quadruplex formation
K Meguellati, G Koripelly, S Ladame
Angewandte Chemie International Edition 49 (15), 2738-2742, 2010
1292010
Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
S Cai, T Pataillot-Meakin, A Shibakawa, R Ren, CL Bevan, S Ladame, ...
Nature Communications 12 (1), 3515, 2021
1142021
First evidence of a functional interaction between DNA quadruplexes and poly (ADP-ribose) polymerase-1
VA Soldatenkov, AA Vetcher, T Duka, S Ladame
ACS chemical biology 3 (4), 214-219, 2008
932008
Templated ligand assembly by using G-quadruplex DNA and dynamic covalent chemistry
AM Whitney, S Ladame, S Balasubramanian
Angewandte Chemie (International ed. in English) 43 (9), 1143, 2004
922004
Molecular methods in electrochemical microRNA detection
P Gillespie, S Ladame, D O'Hare
Analyst 144 (1), 114-129, 2019
842019
G-Quadruplex-specific peptide− hemicyanine ligands by partial combinatorial selection
JA Schouten, S Ladame, SJ Mason, MA Cooper, S Balasubramanian
Journal of the American Chemical Society 125 (19), 5594-5595, 2003
822003
Synthesis and G-quadruplex binding studies of new 4-N-methylpyridinium porphyrins
DPN Gonçalves, S Ladame, S Balasubramanian, JKM Sanders
Organic & biomolecular chemistry 4 (17), 3337-3342, 2006
802006
Targeting nucleic acid secondary structures with polyamides using an optimized dynamic combinatorial approach
S Ladame, AM Whitney, S Balasubramanian
Angewandte Chemie (International ed. in English) 44 (35), 5736, 2005
782005
Recognition and discrimination of DNA quadruplexes by acridine-peptide conjugates
JE Redman, JM Granadino-Roldan, JA Schouten, S Ladame, AP Reszka, ...
Organic & biomolecular chemistry 7 (1), 76-84, 2009
752009
Combining G‐Quadruplex Targeting Motifs on a Single Peptide Nucleic Acid Scaffold: A Hybrid (3+ 1) PNA–DNA Bimolecular Quadruplex
A Paul, P Sengupta, Y Krishnan, S Ladame
Chemistry–A European Journal 14 (28), 8682-8689, 2008
742008
New glycosidase substrates for droplet-based microfluidic screening
M Najah, E Mayot, IP Mahendra-Wijaya, AD Griffiths, S Ladame, ...
Analytical chemistry 85 (20), 9807-9814, 2013
722013
Synthesis and spectroscopic and DNA-binding properties of fluorogenic acridine-containing cyanine dyes
T Mahmood, A Paul, S Ladame
The Journal of Organic Chemistry 75 (1), 204-207, 2010
642010
Single molecule trapping and sensing using dual nanopores separated by a zeptoliter nanobridge
P Cadinu, B Paulose Nadappuram, DJ Lee, JYY Sze, G Campolo, ...
Nano letters 17 (10), 6376-6384, 2017
632017
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