| Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 536 | 2018 |
| The Emerging Picture of Autism Spectrum Disorder: Genetics and Pathology JA Chen, O Peñagarikano, TG Belgard, V Swarup, DH Geschwind Annual Review of Pathology: Mechanisms of Disease 10, 111-144, 2015 | 318 | 2015 |
| SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β SH Cho, JA Chen, F Sayed, ME Ward, F Gao, TA Nguyen, G Krabbe, ... Journal of Neuroscience 35 (2), 807-818, 2015 | 261 | 2015 |
| Machine learning for large-scale wearable sensor data in Parkinson's disease: Concepts, promises, pitfalls, and futures. KJ Kubota, JA Chen, MA Little Movement Disorders 31 (9), 1314-1326, 2016 | 226 | 2016 |
| Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome AY Huang, D Yu, LK Davis, JH Sul, F Tsetsos, V Ramensky, I Zelaya, ... Neuron 94 (6), 1101-1111. e7, 2017 | 172 | 2017 |
| A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the … SJ van der Lee, OJ Conway, I Jansen, MM Carrasquillo, L Kleineidam, ... Acta neuropathologica 138 (2), 237-250, 2019 | 103 | 2019 |
| A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction A Lopez, SE Lee, K Wojta, EM Ramos, E Klein, J Chen, AL Boxer, ... Brain 140 (4), 1128-1146, 2017 | 98 | 2017 |
| Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases JA Chen, Z Chen, H Won, AY Huang, JK Lowe, K Wojta, JS Yokoyama, ... Molecular neurodegeneration 13 (1), 41, 2018 | 89 | 2018 |
| A Rare Mutation of β1-Adrenergic Receptor Affects Sleep/Wake Behaviors G Shi, L Xing, D Wu, BJ Bhattacharyya, CR Jones, T McMahon, ... Neuron 103 (6), 1044-1055. e7, 2019 | 86 | 2019 |
| Artificial intelligence in the management of glioma: era of personalized medicine H Sotoudeh, O Shafaat, JD Bernstock, MD Brooks, GA Elsayed, JA Chen, ... Frontiers in oncology 9, 768, 2019 | 86 | 2019 |
| An epigenetic signature in peripheral blood associated with the haplotype on 17q21. 31, a risk factor for neurodegenerative tauopathy Y Li, JA Chen, RL Sears, F Gao, ED Klein, A Karydas, MD Geschwind, ... PLoS Genet 10 (3), e1004211, 2014 | 80 | 2014 |
| A Multiancestral Genome-Wide Exome Array Study of Alzheimer Disease, Frontotemporal Dementia, and Progressive Supranuclear Palsy JA Chen, Q Wang, J Davis-Turak, Y Li, AM Karydas, SC Hsu, RL Sears, ... JAMA neurology 72 (4), 414-422, 2015 | 50 | 2015 |
| Genome-wide association study identifies MAPT locus influencing human plasma tau levels J Chen, JT Yu, K Wojta, HF Wang, H Zetterberg, K Blennow, ... Neurology 88 (7), 669-676, 2017 | 42 | 2017 |
| Suboccipital craniotomy for Chiari I results in evoked potential conduction changes JA Chen, PE Coutin-Churchman, MR Nuwer, JA Lazareff Surgical Neurology International 3 (1), 165, 2012 | 34 | 2012 |
| Genome‐wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy Z Chen, JA Chen, A Shatunov, AR Jones, SN Kravitz, AY Huang, ... Movement Disorders 34 (7), 1049-1059, 2019 | 30 | 2019 |
| Cerebellar tonsil ectopia measurement in type I Chiari malformation patients show poor inter-operator reliability BJ Lawrence, A Urbizu, PA Allen, F Loth, RS Tubbs, AC Bunck, JR Kröger, ... Fluids and Barriers of the CNS 15 (1), 33, 2018 | 27 | 2018 |
| Neurodegenerative disease biomarkers Aβ1–40, Aβ1–42, tau, and p‐tau181 in the vervet monkey cerebrospinal fluid: Relation to normal aging, genetic influences, and cerebral … JA Chen, SC Fears, AJ Jasinska, A Huang, NB Al‐Sharif, KE Scheibel, ... Brain and Behavior, 2018 | 27 | 2018 |
| Upright CT scanner WB Chen, JA Chen US Patent 7,003,070, 2006 | 27 | 2006 |
| The truth and coherence behind the concept of overdrainage of cerebrospinal fluid in hydrocephalic patients S Cheok, J Chen, J Lazareff Child's Nervous System 30 (4), 599-606, 2014 | 25 | 2014 |
| A novel in situ multiplex immunofluorescence panel for the assessment of tumor immunopathology and response to virotherapy in pediatric glioblastoma reveals a role for … JD Bernstock, N Vicario, L Rong, PA Valdes, BD Choi, JA Chen, D DiToro, ... OncoImmunology 8 (12), e1678921, 2019 | 24 | 2019 |
