Marc Gielen
Marc Gielen
CNRS permanent researcher - Institut Pasteur
Adresse e-mail validée de pasteur.fr - Page d'accueil
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Mechanism of differential control of NMDA receptor activity by NR2 subunits
M Gielen, BS Retchless, L Mony, JW Johnson, P Paoletti
Nature 459 (7247), 703-707, 2009
3052009
Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor
T Boulin, M Gielen, JE Richmond, DC Williams, P Paoletti, JL Bessereau
Proceedings of the National Academy of Sciences 105 (47), 18590-18595, 2008
1552008
Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition
M Gielen, A Le Goff, D Stroebel, JW Johnson, J Neyton, P Paoletti
Neuron 57 (1), 80-93, 2008
1232008
The desensitization gate of inhibitory Cys-loop receptors
M Gielen, P Thomas, TG Smart
Nature communications 6 (1), 1-10, 2015
912015
Benzodiazepines modulate GABAA receptors by regulating the preactivation step after GABA binding
MC Gielen, MJ Lumb, TG Smart
Journal of Neuroscience 32 (17), 5707-5715, 2012
902012
Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites
D Laverty, P Thomas, M Field, OJ Andersen, MG Gold, PC Biggin, ...
Nature structural & molecular biology 24 (11), 977, 2017
832017
The dual‐gate model for pentameric ligand‐gated ion channels activation and desensitization
M Gielen, PJ Corringer
The Journal of Physiology 596 (10), 1873-1902, 2018
302018
Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation
ME Wilkins, A Caley, MC Gielen, RJ Harvey, TG Smart
The Journal of physiology 594 (13), 3589-3607, 2016
72016
Fonctionnement des récepteurs-canaux du glutamate-Des proteines responsables de la transmission synaptique excitatrice
M Gielen
médecine/sciences 26 (1), 65-72, 2010
62010
Molecular operation of ionotropic glutamate receptors: proteins that mediate the excitatory synaptic neurotransmission
M Gielen
Medecine Sciences: M/S 26 (1), 65-72, 2010
62010
Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors
MS Prevost, H Bouchenaki, N Barilone, M Gielen, PJ Corringer
Cell Mol Life Sci: in press. doi 10, s00018-020, 2020
42020
The desensitization pathway of GABAA receptors, one subunit at a time
M Gielen, N Barilone, PJ Corringer
bioRxiv, 2020
12020
Alterations in nicotinic receptor alpha5 subunit gene differentially impact early and later stages of cocaine addiction: a translational study in transgenic rats and patients
B Forget, R Icick, J Robert, C Correia, MS Prevost, M Gielen, PJ Corringer, ...
Progress in Neurobiology, 101898, 2020
2020
Allosteric Transitions of Pentameric Ligand-Gated Ion Channels Studied by Fluorescence Quenching to Explore Pathological Mutations and Pharmacological Effectors
SN Lefebvre, A Menny, M Gielen, PJ Corringer
Biophysical Journal 116 (3), 396a, 2019
2019
Mécanismes moléculaires du contrôle de l'activité des récepteurs NMDA
M Gielen
Paris 6, 2009
2009
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