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Marc Gielen
Marc Gielen
CNRS permanent researcher - Institut Pasteur
Adresse e-mail validée de pasteur.fr - Page d'accueil
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Mechanism of differential control of NMDA receptor activity by NR2 subunits
M Gielen, BS Retchless, L Mony, JW Johnson, P Paoletti
Nature 459 (7247), 703-707, 2009
3852009
Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor
T Boulin, M Gielen, JE Richmond, DC Williams, P Paoletti, JL Bessereau
Proceedings of the National Academy of Sciences 105 (47), 18590-18595, 2008
2222008
Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites
D Laverty, P Thomas, M Field, OJ Andersen, MG Gold, PC Biggin, ...
Nature structural & molecular biology 24 (11), 977-985, 2017
1822017
The desensitization gate of inhibitory Cys-loop receptors
M Gielen, P Thomas, TG Smart
Nature communications 6 (1), 6829, 2015
1422015
Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition
M Gielen, A Le Goff, D Stroebel, JW Johnson, J Neyton, P Paoletti
Neuron 57 (1), 80-93, 2008
1422008
Benzodiazepines modulate GABAA receptors by regulating the preactivation step after GABA binding
MC Gielen, MJ Lumb, TG Smart
Journal of Neuroscience 32 (17), 5707-5715, 2012
1272012
The dual‐gate model for pentameric ligand‐gated ion channels activation and desensitization
M Gielen, PJ Corringer
The Journal of Physiology 596 (10), 1873-1902, 2018
1072018
The desensitization pathway of GABAA receptors, one subunit at a time
M Gielen, N Barilone, PJ Corringer
Nature communications 11 (1), 5369, 2020
222020
Fonctionnement des récepteurs-canaux du glutamate-Des proteines responsables de la transmission synaptique excitatrice
M Gielen
médecine/sciences 26 (1), 65-72, 2010
17*2010
Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors
MS Prevost, H Bouchenaki, N Barilone, M Gielen, PJ Corringer
Cellular and Molecular Life Sciences 78, 1051-1064, 2021
162021
Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation
ME Wilkins, A Caley, MC Gielen, RJ Harvey, TG Smart
The Journal of Physiology 594 (13), 3589-3607, 2016
92016
Alterations in nicotinic receptor alpha5 subunit gene differentially impact early and later stages of cocaine addiction: a translational study in transgenic rats and patients
B Forget, R Icick, J Robert, C Correia, MS Prevost, M Gielen, PJ Corringer, ...
Progress in Neurobiology 197, 101898, 2021
72021
Illumination of a progressive allosteric mechanism mediating the glycine receptor activation
S Shi, SN Lefebvre, L Peverini, AH Cerdan, P Milán Rodríguez, M Gielen, ...
Nature Communications 14 (1), 795, 2023
32023
Conformational state-dependent regulation of GABAA receptor diffusion and subsynaptic domains
Z Merlaud, X Marques, M Russeau, U Saade, M Tostain, I Moutkine, ...
Iscience 25 (11), 2022
32022
An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies
MS Prevost, N Barilone, G Dejean De La Batie, S Pons, G Ayme, ...
Nature Communications 14 (1), 5964, 2023
12023
Influence of the open, closed or desensitized states of the GABAA receptor on its membrane dynamics and accumulation at inhibitory synapses
M Renner, Z Merlaud, X Marques, M Russeau, I Moutkine, E François, ...
Conférences Jacques Monod, 2019
2019
Mechanistic insights into allosteric modulation of NMDA receptors
P Paoletti, L Mony, D Stroebel, M Gielen
FUNDAMENTAL & CLINICAL PHARMACOLOGY 22, 28-28, 2008
2008
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