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Anna-Lena Steckelberg
Anna-Lena Steckelberg
Assistant Professor, Columbia University Irving Medical Center
Adresse e-mail validée de cumc.columbia.edu
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CWC22 connects pre-mRNA splicing and exon junction complex assembly
AL Steckelberg, V Boehm, AM Gromadzka, NH Gehring
Cell reports 2 (3), 454-461, 2012
1202012
A short conserved motif in ALYREF directs cap-and EJC-dependent assembly of export complexes on spliced mRNAs
AM Gromadzka, AL Steckelberg, KK Singh, K Hofmann, NH Gehring
Nucleic acids research 44 (5), 2348-2361, 2016
802016
A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure
AL Steckelberg, BM Akiyama, DA Costantino, TL Sit, JC Nix, JS Kieft
Proceedings of the National Academy of Sciences 115 (25), 6404-6409, 2018
712018
Exon junction complexes suppress spurious splice sites to safeguard transcriptome integrity
V Boehm, T Britto-Borges, AL Steckelberg, KK Singh, JV Gerbracht, ...
Molecular cell 72 (3), 482-495. e7, 2018
662018
NKAP is a novel RS-related protein that interacts with RNA and RNA binding proteins
BD Burgute, VS Peche, AL Steckelberg, G Glöckner, B Gaßen, ...
Nucleic acids research 42 (5), 3177-3193, 2014
492014
Exoribonuclease-resistant RNAs exist within both coding and noncoding subgenomic RNAs
AL Steckelberg, Q Vicens, JS Kieft
MBio 9 (6), 10.1128/mbio. 02461-18, 2018
432018
CWC22-dependent pre-mRNA splicing and eIF4A3 binding enables global deposition of exon junction complexes
AL Steckelberg, J Altmueller, C Dieterich, NH Gehring
Nucleic acids research 43 (9), 4687-4700, 2015
372015
Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA
RA Jones, AL Steckelberg, Q Vicens, MJ Szucs, BM Akiyama, JS Kieft
Rna 27 (1), 54-65, 2021
342021
The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold
AL Steckelberg, Q Vicens, DA Costantino, JC Nix, JS Kieft
Rna 26 (12), 1767-1776, 2020
252020
Evaluating ribosomal frameshifting in CCR5 mRNA decoding
YA Khan, G Loughran, AL Steckelberg, K Brown, SJ Kiniry, H Stewart, ...
Nature 604 (7906), E16-E23, 2022
222022
Exoribonuclease-resistant RNAs exist within both coding and noncoding subgenomic RNAs. mBio 9: e02461-18
AL Steckelberg, Q Vicens, JS Kieft
112018
Studying the composition of mRNPs in vitro using splicing-competent cell extracts
AL Steckelberg, NH Gehring
Methods 65 (3), 342-349, 2014
82014
Long 3′ UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation
TJ Dorrity, H Shin, KA Wiegand, J Aruda, M Closser, E Jung, JA Gertie, ...
Science Immunology 8 (88), eadg2979, 2023
52023
Different tertiary interactions create the same important 3-D features in a divergent flavivirus xrRNA
RA Jones, AL Steckelberg, MJ Szucs, BM Akiyama, Q Vicens, JS Kieft
BioRxiv, 2020.06. 25.172429, 2020
32020
Pervasiveness of exoribonuclease-resistant RNAs in plant viruses suggests new roles for these conserved RNA structures
AL Steckelberg, Q Vicens, JS Kieft
bioRxiv, 433672, 2018
22018
An evolutionarily conserved strategy for ribosome binding and host translation inhibition by β-coronavirus Non-structural Protein 1
SF Maurina, JP O'Sullivan, G Sharma, DCP Rodriguez, A MacFadden, ...
Journal of Molecular Biology 435 (20), 168259, 2023
12023
Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR)
G Loughran, DE Andreev, IM Terenin, O Namy, M Mikl, MM Yordanova, ...
2024
The ART of RNAylation: covalent RNA–protein linkage in bacteriophage infection
SM Korn, S Sharma, AL Steckelberg
Trends in Biochemical Sciences, 2023
2023
An evolutionarily conserved strategy for ribosome binding and inhibition by β-coronavirus non-structural protein 1
SF Maurina, JP O’Sullivan, G Sharma, DCP Rodriguez, A MacFadden, ...
bioRxiv, 2023
2023
CWC22 Supports Pre-mRNA Splicing and Exon Junction Complex Assembly
AL Steckelberg
Universität zu Köln, 2014
2014
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