Suivre
Timothy M. Miller
Timothy M. Miller
Professor of Neurology, Washington University
Adresse e-mail validée de wustl.edu - Page d'accueil
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Unraveling the mechanisms involved in motor neuron degeneration in ALS
LI Bruijn, TM Miller, DW Cleveland
Annu. Rev. Neurosci. 27, 723-749, 2004
16682004
Distinct tau prion strains propagate in cells and mice and define different tauopathies
DW Sanders, SK Kaufman, SL DeVos, AM Sharma, H Mirbaha, A Li, ...
Neuron 82 (6), 1271-1288, 2014
10142014
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
BB Holmes, SL DeVos, N Kfoury, M Li, R Jacks, K Yanamandra, ...
Proceedings of the National Academy of Sciences 110 (33), E3138-E3147, 2013
8562013
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
T Zu, Y Liu, M Bañez-Coronel, T Reid, O Pletnikova, J Lewis, TM Miller, ...
Proceedings of the National Academy of Sciences 110 (51), E4968-E4977, 2013
8382013
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
I Wegorzewska, S Bell, NJ Cairns, TM Miller, RH Baloh
Proceedings of the National Academy of Sciences 106 (44), 18809-18814, 2009
8132009
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study
TM Miller, A Pestronk, W David, J Rothstein, E Simpson, SH Appel, ...
The Lancet Neurology 12 (5), 435-442, 2013
6742013
Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria
J Liu, C Lillo, PA Jonsson, CV Velde, CM Ward, TM Miller, ...
Neuron 43 (1), 5-17, 2004
6362004
C9orf72 is required for proper macrophage and microglial function in mice
JG O’rourke, L Bogdanik, A Yáñez, D Lall, AJ Wolf, A Muhammad, R Ho, ...
Science 351 (6279), 1324-1329, 2016
5852016
Antisense oligonucleotide therapy for neurodegenerative disease
RA Smith, TM Miller, K Yamanaka, BP Monia, TP Condon, G Hung, ...
The Journal of clinical investigation 116 (8), 2290-2296, 2006
5802006
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1268-1283. e6, 2018
5782018
Tau kinetics in neurons and the human central nervous system
C Sato, NR Barthélemy, KG Mawuenyega, BW Patterson, BA Gordon, ...
Neuron 97 (6), 1284-1298. e7, 2018
5302018
Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death
TM Miller, KL Moulder, CM Knudson, DJ Creedon, M Deshmukh, ...
The Journal of cell biology 139 (1), 205-217, 1997
4561997
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ...
New England Journal of Medicine 383 (2), 109-119, 2020
4362020
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
SL DeVos, RL Miller, KM Schoch, BB Holmes, CS Kebodeaux, ...
Science translational medicine 9 (374), eaag0481, 2017
4302017
Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo
SK Kaufman, DW Sanders, TL Thomas, AJ Ruchinskas, J Vaquer-Alicea, ...
Neuron 92 (4), 796-812, 2016
4092016
Trial of sodium phenylbutyrate–taurursodiol for amyotrophic lateral sclerosis
S Paganoni, EA Macklin, S Hendrix, JD Berry, MA Elliott, S Maiser, ...
New England Journal of Medicine 383 (10), 919-930, 2020
4032020
Myopathy with antibodies to the signal recognition particle: clinical and pathological features
T Miller, MT Al-Lozi, G Lopate, A Pestronk
Journal of Neurology, Neurosurgery & Psychiatry 73 (4), 420-428, 2002
3702002
Muscle cramps
TM Miller, RB Layzer
Muscle & Nerve: Official Journal of the American Association of …, 2005
3382005
Antisense reduction of tau in adult mice protects against seizures
SL DeVos, DK Goncharoff, G Chen, CS Kebodeaux, K Yamada, ...
Journal of Neuroscience 33 (31), 12887-12897, 2013
3352013
Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria
C Vande Velde, TM Miller, NR Cashman, DW Cleveland
Proceedings of the National Academy of Sciences 105 (10), 4022-4027, 2008
3312008
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