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Bernard Pirotte
Bernard Pirotte
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New trends in dual 5-LOX/COX inhibition
X Leval, F Julemont, J Delarge, B Pirotte, JM Dogne
Current Medicinal Chemistry 9 (9), 941-962, 2002
1472002
3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo
I Kempen, D Papapostolou, N Thierry, L Pochet, S Counerotte, ...
British Journal of Cancer 88 (7), 1111-1118, 2003
1402003
Insight into SUCNR1 (GPR91) structure and function
J Gilissen, F Jouret, B Pirotte, J Hanson
Pharmacology & therapeutics 159, 56-65, 2016
1322016
Study of the influence of both cyclodextrins and L-lysine on the aqueous solubility of nimesulide; isolation and characterization of nimesulide–L-lysine–cyclodextrin complexes
G Piel, B Pirotte, I Delneuville, P Neven, G Llabres, J Delarge, L Delattre
Journal of pharmaceutical sciences 86 (4), 475-480, 1997
1261997
Esters and Amides of 6-(Chloromethyl)-2-oxo-2H-1-benzopyran-3-carboxylic Acid as Inhibitors of α-Chymotrypsin:  Significance of the “Aromatic” Nature of the …
L Pochet, C Doucet, M Schynts, N Thierry, N Boggetto, B Pirotte, KY Jiang, ...
Journal of medicinal chemistry 39 (13), 2579-2585, 1996
1221996
New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators
JM Dogné, X Leval, J Hanson, M Frederich, B Lambermont, A Ghuysen, ...
Current medicinal chemistry 11 (10), 1223-1241, 2004
1102004
New developments on thromboxane and prostacyclin modulators part II: prostacyclin modulators
X Leval, J Hanson, JL David, B Masereel, B Pirotte, JM Dogné
Current medicinal chemistry 11 (10), 1243-1252, 2004
1072004
Inhibition of LTβR signalling activates WNT-induced regeneration in lung
TM Conlon, G John-Schuster, D Heide, D Pfister, M Lehmann, Y Hu, ...
Nature 588 (7836), 151-156, 2020
1022020
Antibacterial activity of ticagrelor in conventional antiplatelet dosages against antibiotic-resistant gram-positive bacteria
P Lancellotti, L Musumeci, N Jacques, L Servais, E Goffin, B Pirotte, ...
JAMA cardiology 4 (6), 596-599, 2019
972019
3-(Alkylamino)-4H-pyrido [4, 3-e] 1, 2, 4-thiadiazine 1, 1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: a new class of potassium channel openers?
B Pirotte, P De Tullio, P Lebrun, MH Antoine, J Fontaine, B Masereel, ...
Journal of medicinal chemistry 36 (21), 3211-3213, 1993
941993
Recent advances in inducible cyclooxygenase (COX-2) inhibition
X Laval, J Delarge, F Somers, P Tullio, Y Henrotin, B Pirotte, JM Dogne
Current medicinal chemistry 7 (10), 1041-1062, 2000
912000
3, 6-Disubstituted coumarins as mechanism-based inhibitors of thrombin and factor Xa
R Frédérick, S Robert, C Charlier, J de Ruyck, J Wouters, B Pirotte, ...
Journal of medicinal chemistry 48 (24), 7592-7603, 2005
852005
6-Substituted 2-Oxo-2H-1-benzopyran-3-carboxylic Acid as a Core Structure for Specific Inhibitors of Human Leukocyte Elastase
C Doucet, L Pochet, N Thierry, B Pirotte, J Delarge, M Reboud-Ravaux
Journal of medicinal chemistry 42 (20), 4161-4171, 1999
831999
Design, Synthesis, and Pharmacology of Novel 7-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of AMPA …
P Francotte, P De Tullio, E Goffin, G Dintilhac, E Graindorge, P Fraikin, ...
Journal of medicinal chemistry 50 (13), 3153-3157, 2007
792007
From the design to the clinical application of thromboxane modulators
JM Dogné, J Hanson, X Leval, D Pratico, CR Pace-Asciak, P Drion, ...
Current pharmaceutical design 12 (8), 903-923, 2006
782006
New trends in the design of drugs against Alzheimer's disease
P Francotte, E Graindorge, S Boverie, P Tullio, B Pirotte
Current medicinal chemistry 11 (13), 1757-1778, 2004
782004
Toward Tissue-Selective Pancreatic B-Cells KATP Channel Openers Belonging to 3-Alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-Dioxides
P De Tullio, B Becker, S Boverie, M Dabrowski, P Wahl, MH Antoine, ...
Journal of medicinal chemistry 46 (15), 3342-3353, 2003
742003
Metabolomics as a challenging approach for medicinal chemistry and personalized medicine
M Frederich, B Pirotte, M Fillet, P De Tullio
Journal of medicinal chemistry 59 (19), 8649-8666, 2016
732016
Recent advances in the chemistry of potassium channel openers
B Pirotte, J Fontaine, P Lebrun
Current medicinal chemistry 2 (1), 573-582, 1995
711995
4H-1,2,4-Pyridothiadiazine 1,1-Dioxides and 2,3-Dihydro-4H-1,2,4-pyridothiadiazine 1,1-Dioxides Chemically Related to Diazoxide and Cyclothiazide as Powerful Positive Allosteric …
B Pirotte, T Podona, O Diouf, P De Tullio, P Lebrun, L Dupont, F Somers, ...
Journal of medicinal chemistry 41 (16), 2946-2959, 1998
691998
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