New trends in dual 5-LOX/COX inhibition X Leval, F Julemont, J Delarge, B Pirotte, JM Dogne Current Medicinal Chemistry 9 (9), 941-962, 2002 | 147 | 2002 |
3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo I Kempen, D Papapostolou, N Thierry, L Pochet, S Counerotte, ... British Journal of Cancer 88 (7), 1111-1118, 2003 | 140 | 2003 |
Insight into SUCNR1 (GPR91) structure and function J Gilissen, F Jouret, B Pirotte, J Hanson Pharmacology & therapeutics 159, 56-65, 2016 | 132 | 2016 |
Study of the influence of both cyclodextrins and L-lysine on the aqueous solubility of nimesulide; isolation and characterization of nimesulide–L-lysine–cyclodextrin complexes G Piel, B Pirotte, I Delneuville, P Neven, G Llabres, J Delarge, L Delattre Journal of pharmaceutical sciences 86 (4), 475-480, 1997 | 126 | 1997 |
Esters and Amides of 6-(Chloromethyl)-2-oxo-2H-1-benzopyran-3-carboxylic Acid as Inhibitors of α-Chymotrypsin: Significance of the “Aromatic” Nature of the … L Pochet, C Doucet, M Schynts, N Thierry, N Boggetto, B Pirotte, KY Jiang, ... Journal of medicinal chemistry 39 (13), 2579-2585, 1996 | 122 | 1996 |
New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators JM Dogné, X Leval, J Hanson, M Frederich, B Lambermont, A Ghuysen, ... Current medicinal chemistry 11 (10), 1223-1241, 2004 | 110 | 2004 |
New developments on thromboxane and prostacyclin modulators part II: prostacyclin modulators X Leval, J Hanson, JL David, B Masereel, B Pirotte, JM Dogné Current medicinal chemistry 11 (10), 1243-1252, 2004 | 107 | 2004 |
Inhibition of LTβR signalling activates WNT-induced regeneration in lung TM Conlon, G John-Schuster, D Heide, D Pfister, M Lehmann, Y Hu, ... Nature 588 (7836), 151-156, 2020 | 102 | 2020 |
Antibacterial activity of ticagrelor in conventional antiplatelet dosages against antibiotic-resistant gram-positive bacteria P Lancellotti, L Musumeci, N Jacques, L Servais, E Goffin, B Pirotte, ... JAMA cardiology 4 (6), 596-599, 2019 | 97 | 2019 |
3-(Alkylamino)-4H-pyrido [4, 3-e] 1, 2, 4-thiadiazine 1, 1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: a new class of potassium channel openers? B Pirotte, P De Tullio, P Lebrun, MH Antoine, J Fontaine, B Masereel, ... Journal of medicinal chemistry 36 (21), 3211-3213, 1993 | 94 | 1993 |
Recent advances in inducible cyclooxygenase (COX-2) inhibition X Laval, J Delarge, F Somers, P Tullio, Y Henrotin, B Pirotte, JM Dogne Current medicinal chemistry 7 (10), 1041-1062, 2000 | 91 | 2000 |
3, 6-Disubstituted coumarins as mechanism-based inhibitors of thrombin and factor Xa R Frédérick, S Robert, C Charlier, J de Ruyck, J Wouters, B Pirotte, ... Journal of medicinal chemistry 48 (24), 7592-7603, 2005 | 85 | 2005 |
6-Substituted 2-Oxo-2H-1-benzopyran-3-carboxylic Acid as a Core Structure for Specific Inhibitors of Human Leukocyte Elastase C Doucet, L Pochet, N Thierry, B Pirotte, J Delarge, M Reboud-Ravaux Journal of medicinal chemistry 42 (20), 4161-4171, 1999 | 83 | 1999 |
Design, Synthesis, and Pharmacology of Novel 7-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of AMPA … P Francotte, P De Tullio, E Goffin, G Dintilhac, E Graindorge, P Fraikin, ... Journal of medicinal chemistry 50 (13), 3153-3157, 2007 | 79 | 2007 |
From the design to the clinical application of thromboxane modulators JM Dogné, J Hanson, X Leval, D Pratico, CR Pace-Asciak, P Drion, ... Current pharmaceutical design 12 (8), 903-923, 2006 | 78 | 2006 |
New trends in the design of drugs against Alzheimer's disease P Francotte, E Graindorge, S Boverie, P Tullio, B Pirotte Current medicinal chemistry 11 (13), 1757-1778, 2004 | 78 | 2004 |
Toward Tissue-Selective Pancreatic B-Cells KATP Channel Openers Belonging to 3-Alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-Dioxides P De Tullio, B Becker, S Boverie, M Dabrowski, P Wahl, MH Antoine, ... Journal of medicinal chemistry 46 (15), 3342-3353, 2003 | 74 | 2003 |
Metabolomics as a challenging approach for medicinal chemistry and personalized medicine M Frederich, B Pirotte, M Fillet, P De Tullio Journal of medicinal chemistry 59 (19), 8649-8666, 2016 | 73 | 2016 |
Recent advances in the chemistry of potassium channel openers B Pirotte, J Fontaine, P Lebrun Current medicinal chemistry 2 (1), 573-582, 1995 | 71 | 1995 |
4H-1,2,4-Pyridothiadiazine 1,1-Dioxides and 2,3-Dihydro-4H-1,2,4-pyridothiadiazine 1,1-Dioxides Chemically Related to Diazoxide and Cyclothiazide as Powerful Positive Allosteric … B Pirotte, T Podona, O Diouf, P De Tullio, P Lebrun, L Dupont, F Somers, ... Journal of medicinal chemistry 41 (16), 2946-2959, 1998 | 69 | 1998 |