| Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease C Moussa, M Hebron, X Huang, J Ahn, RA Rissman, PS Aisen, RS Turner Journal of neuroinflammation 14, 1-10, 2017 | 578 | 2017 |
| Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models ML Hebron, I Lonskaya, CEH Moussa Human molecular genetics 22 (16), 3315-3328, 2013 | 337 | 2013 |
| Nilotinib effects in Parkinson’s disease and dementia with Lewy bodies F Pagan, M Hebron, EH Valadez, Y Torres-Yaghi, X Huang, RR Mills, ... Journal of Parkinson's disease 6 (3), 503-517, 2016 | 257 | 2016 |
| Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance I Lonskaya, ML Hebron, NM Desforges, JB Schachter, CEH Moussa Journal of molecular medicine 92, 373-386, 2014 | 140 | 2014 |
| Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6) ML Hebron, I Lonskaya, K Sharpe, PPK Weerasinghe, NK Algarzae, ... Journal of Biological Chemistry 288 (6), 4103-4115, 2013 | 139 | 2013 |
| Nilotinib effects on safety, tolerability, and potential biomarkers in Parkinson disease: a phase 2 randomized clinical trial FL Pagan, ML Hebron, B Wilmarth, Y Torres-Yaghi, A Lawler, EE Mundel, ... JAMA neurology 77 (3), 309-317, 2020 | 137 | 2020 |
| Tyrosine kinase inhibition increases functional parkin‐B eclin‐1 interaction and enhances amyloid clearance and cognitive performance I Lonskaya, ML Hebron, NM Desforges, A Franjie, CEH Moussa EMBO molecular medicine 5 (8), 1247-1262, 2013 | 137 | 2013 |
| Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease I Lonskaya, AR Shekoyan, ML Hebron, N Desforges, NK Algarzae, ... Journal of Alzheimer's Disease 33 (1), 231-247, 2013 | 94 | 2013 |
| Nilotinib effects on safety, tolerability, and biomarkers in Alzheimer's disease RS Turner, ML Hebron, A Lawler, EE Mundel, N Yusuf, JN Starr, M Anjum, ... Annals of neurology 88 (1), 183-194, 2020 | 89 | 2020 |
| Pharmacokinetics and pharmacodynamics of a single dose Nilotinib in individuals with Parkinson's disease FL Pagan, ML Hebron, B Wilmarth, Y Torres‐Yaghi, A Lawler, EE Mundel, ... Pharmacology Research & Perspectives 7 (2), e00470, 2019 | 87 | 2019 |
| Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer’s disease models I Lonskaya, ML Hebron, ST Selby, RS Turner, CEH Moussa Neuroscience 304, 316-327, 2015 | 82 | 2015 |
| Ubiquitination increases parkin activity to promote autophagic α-synuclein clearance I Lonskaya, NM Desforges, ML Hebron, CEH Moussa PloS one 8 (12), e83914, 2013 | 82 | 2013 |
| Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson’s disease I Lonskaya, ML Hebron, NK Algarzae, N Desforges, CEH Moussa Neuroscience 232, 90-105, 2013 | 80 | 2013 |
| Tyrosine kinase inhibition regulates early systemic immune changes and modulates the neuroimmune response in α-synucleinopathy ML Hebron, I Lonskaya, P Olopade, ST Selby, F Pagan, CEH Moussa Journal of clinical & cellular immunology 5, 259, 2014 | 67 | 2014 |
| Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance ML Hebron, I Lonskaya, CEH Moussa Autophagy 9 (8), 1249-1250, 2013 | 61 | 2013 |
| Tau deletion impairs intracellular β-amyloid-42 clearance and leads to more extracellular plaque deposition in gene transfer models I Lonskaya, M Hebron, W Chen, J Schachter, C Moussa Molecular neurodegeneration 9, 1-16, 2014 | 58 | 2014 |
| Ubiquitin specific protease-13 independently regulates parkin ubiquitination and alpha-synuclein clearance in alpha-synucleinopathies X Liu, M Hebron, W Shi, I Lonskaya, CEH Moussa Human molecular genetics 28 (4), 548-560, 2019 | 55 | 2019 |
| Multikinase Abl/DDR/Src inhibition produces optimal effects for tyrosine kinase inhibition in neurodegeneration AJ Fowler, M Hebron, AA Missner, R Wang, X Gao, BT Kurd-Misto, X Liu, ... Drugs in R&D 19, 149-166, 2019 | 52 | 2019 |
| Discoidin domain receptor inhibition reduces neuropathology and attenuates inflammation in neurodegeneration models M Hebron, M Peyton, X Liu, X Gao, R Wang, I Lonskaya, CEH Moussa Journal of neuroimmunology 311, 1-9, 2017 | 46 | 2017 |
| Tau clearance improves astrocytic function and brain glutamate-glutamine cycle ML Hebron, M Javidnia, CEH Moussa Journal of the neurological sciences 391, 90-99, 2018 | 45 | 2018 |
