| Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling N Aznar, KK Midde, Y Dunkel, I Lopez-Sanchez, Y Pavlova, A Marivin, ... Elife 4, e07091, 2015 | 124 | 2015 |
| Human VRK1 is an early response gene and its loss causes a block in cell cycle progression A Valbuena, I López-Sánchez, PA Lazo PloS one 3 (2), e1642, 2008 | 113 | 2008 |
| GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis I Lopez-Sanchez, Y Dunkel, YS Roh, Y Mittal, S De Minicis, A Muranyi, ... Nature communications 5 (1), 4451, 2014 | 107 | 2014 |
| Roles of VRK1 as a new player in the control of biological processes required for cell division A Valbuena, M Sanz-García, I López-Sánchez, FM Vega, PA Lazo Cellular signalling 23 (8), 1267-1272, 2011 | 97 | 2011 |
| Plk3 Interacts with and Specifically Phosphorylates VRK1 in Ser342, a Downstream Target in a Pathway That Induces Golgi Fragmentation I López-Sánchez, M Sanz-García, PA Lazo Molecular and cellular biology 29 (5), 1189-1201, 2009 | 79 | 2009 |
| Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration–proliferation dichotomy D Bhandari, I Lopez-Sanchez, A To, IC Lo, N Aznar, A Leyme, V Gupta, ... Proceedings of the National Academy of Sciences 112 (35), E4874-E4883, 2015 | 65 | 2015 |
| Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations A Valbuena, I Lopez-Sánchez, FM Vega, A Sevilla, M Sanz-García, ... Archives of biochemistry and biophysics 465 (1), 219-226, 2007 | 65 | 2007 |
| Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities M Sanz-Garciéa, I Loépez-Saénchez, PA Lazo Molecular & Cellular Proteomics 7 (11), 2199-2214, 2008 | 61 | 2008 |
| Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin C Lin, J Ear, K Midde, I Lopez-Sanchez, N Aznar, M Garcia-Marcos, ... Molecular biology of the cell 25 (22), 3654-3671, 2014 | 59 | 2014 |
| VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage I López-Sánchez, A Valbuena, M Vázquez-Cedeira, J Khadake, ... FEBS letters 588 (5), 692-700, 2014 | 50 | 2014 |
| Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin I López-Sánchez, M Garcia-Marcos, Y Mittal, N Aznar, MG Farquhar, ... Proceedings of the National Academy of Sciences 110 (14), 5510-5515, 2013 | 49 | 2013 |
| Activation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling IC Lo, V Gupta, KK Midde, V Taupin, I Lopez-Sanchez, I Kufareva, ... Developmental cell 33 (2), 189-203, 2015 | 47 | 2015 |
| Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors GS Ma, N Aznar, N Kalogriopoulos, KK Midde, I Lopez-Sanchez, E Sato, ... Proceedings of the National Academy of Sciences 112 (20), E2602-E2610, 2015 | 43 | 2015 |
| GIV/Girdin activates Gαi and inhibits Gαs via the same motif V Gupta, D Bhandari, A Leyme, N Aznar, KK Midde, IC Lo, J Ear, ... Proceedings of the National Academy of Sciences 113 (39), E5721-E5730, 2016 | 38 | 2016 |
| Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple N Aznar, J Ear, Y Dunkel, N Sun, K Satterfield, F He, NA Kalogriopoulos, ... Science signaling 11 (519), eaao4220, 2018 | 32 | 2018 |
| Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins I Lopez-Sanchez, N Kalogriopoulos, IC Lo, F Kabir, KK Midde, H Wang, ... Molecular biology of the cell 26 (24), 4313-4324, 2015 | 25 | 2015 |
| Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi NA Kalogriopoulos, I Lopez-Sanchez, C Lin, T Ngo, KK Midde, S Roy, ... Proceedings of the National Academy of Sciences 117 (46), 28763-28774, 2020 | 24 | 2020 |
| Identification of noncanonical Wnt receptors required for Wnt-3a-induced early differentiation of human neural stem cells N Bengoa-Vergniory, I Gorroño-Etxebarria, I López-Sánchez, M Marra, ... Molecular Neurobiology 54, 6213-6224, 2017 | 20 | 2017 |
| Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation DS Moura, IF Fernández, G Marín-Royo, I López-Sánchez, ... Scientific reports 6 (1), 28532, 2016 | 19 | 2016 |
| Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity GS Ma, I Lopez-Sanchez, N Aznar, N Kalogriopoulos, S Pedram, K Midde, ... Molecular biology of the cell 26 (23), 4209-4223, 2015 | 17 | 2015 |
