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Erik Tucker
Erik Tucker
CEO, Aronora
Adresse e-mail validée de aronorabio.com
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A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo
Q Cheng, EI Tucker, MS Pine, I Sisler, A Matafonov, M Sun, ...
Blood, The Journal of the American Society of Hematology 116 (19), 3981-3989, 2010
2982010
Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI
EI Tucker, UM Marzec, TC White, S Hurst, S Rugonyi, OJT McCarty, ...
Blood, The Journal of the American Society of Hematology 113 (4), 936-944, 2009
2372009
Factor XII inhibition reduces thrombus formation in a primate thrombosis model
A Matafonov, PY Leung, AE Gailani, SL Grach, C Puy, Q Cheng, M Sun, ...
Blood, The Journal of the American Society of Hematology 123 (11), 1739-1746, 2014
2282014
Factor XI contributes to thrombin generation in the absence of factor XII
DV Kravtsov, A Matafonov, EI Tucker, M Sun, PN Walsh, A Gruber, ...
Blood, The Journal of the American Society of Hematology 114 (2), 452-458, 2009
1782009
Red blood cell–derived microparticles isolated from blood units initiate and propagate thrombin generation
O Rubin, J Delobel, M Prudent, N Lion, K Kohl, EI Tucker, JD Tissot, ...
Transfusion 53 (8), 1744-1754, 2013
1752013
Antithrombotic effect of antisense factor XI oligonucleotide treatment in primates
JR Crosby, U Marzec, AS Revenko, C Zhao, D Gao, A Matafonov, ...
Arteriosclerosis, thrombosis, and vascular biology 33 (7), 1670-1678, 2013
1622013
von Willebrand Disease in a Pediatric-based Population-Comparison of Type 1 Diagnostic Criteria and Use of the PFA-100® and a von Willebrand Factor/Collagen-binding Assay
JA Dean, VS Blanchette, MD Carcao, AM Stain, CR Sparling, J Siekmann, ...
Thrombosis and haemostasis 84 (09), 401-409, 2000
1572000
Factor XII promotes blood coagulation independent of factor XI in the presence of long‐chain polyphosphates
C Puy, EI Tucker, ZC Wong, D Gailani, SA Smith, SH Choi, JH Morrissey, ...
Journal of thrombosis and haemostasis 11 (7), 1341-1352, 2013
1132013
Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis
EI Tucker, NG Verbout, PY Leung, S Hurst, OJT McCarty, D Gailani, ...
Blood, The Journal of the American Society of Hematology 119 (20), 4762-4768, 2012
1112012
New developments in anticoagulants: past, present and future
JI Weitz, J Harenberg
Thrombosis and haemostasis 117 (07), 1283-1288, 2017
1092017
Blood coagulation and blood–material interactions
SR Hanson, EI Tucker, RA Latour
Biomaterials science, 801-812, 2020
1012020
Laminin promotes coagulation and thrombus formation in a factor XII‐dependent manner
TC White‐Adams, MA Berny, IA Patel, EI Tucker, D Gailani, A Gruber, ...
Journal of Thrombosis and Haemostasis 8 (6), 1295-1301, 2010
812010
Evidence for factor IX‐independent roles for factor XIa in blood coagulation
A Matafonov, Q Cheng, Y Geng, IM Verhamme, O Umunakwe, EI Tucker, ...
Journal of Thrombosis and Haemostasis 11 (12), 2118-2127, 2013
802013
Contact activation inhibitor and factor XI antibody, AB023, produces safe, dose-dependent anticoagulation in a phase 1 first-in-human trial
CU Lorentz, NG Verbout, M Wallisch, MW Hagen, JJ Shatzel, SR Olson, ...
Arteriosclerosis, thrombosis, and vascular biology 39 (4), 799-809, 2019
782019
Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2)
TC White-Adams, MA Berny, EI Tucker, JM Gertz, D Gailani, RT Urbanus, ...
Arteriosclerosis, thrombosis, and vascular biology 29 (10), 1602-1607, 2009
772009
Protein C supports platelet binding and activation under flow: role of glycoprotein Ib and apolipoprotein E receptor 2
TC White, MA Berny, EI Tucker, RT Urbanus, PG De Groot, JA Fernandez, ...
Journal of Thrombosis and Haemostasis 6 (6), 995-1002, 2008
762008
The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial
CU Lorentz, EI Tucker, NG Verbout, JJ Shatzel, SR Olson, BD Markway, ...
Blood, The Journal of the American Society of Hematology 138 (22), 2173-2184, 2021
712021
Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor
C Puy, EI Tucker, A Matafonov, Q Cheng, KD Zientek, D Gailani, A Gruber, ...
Blood, The Journal of the American Society of Hematology 125 (9), 1488-1496, 2015
712015
Survival advantage of coagulation factor XI-deficient mice during peritoneal sepsis
EI Tucker, D Gailani, S Hurst, Q Cheng, SR Hanson, A Gruber
The Journal of infectious diseases 198 (2), 271-274, 2008
712008
Inhibition of factor XII-mediated activation of factor XI provides protection against experimental acute ischemic stroke in mice
PY Leung, S Hurst, MA Berny-Lang, NG Verbout, D Gailani, EI Tucker, ...
Translational stroke research 3, 381-389, 2012
642012
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